CAS-Net: Conditional Atlas Generation and Brain Segmentation for Fetal
MRI
- URL: http://arxiv.org/abs/2205.08239v1
- Date: Tue, 17 May 2022 11:23:02 GMT
- Title: CAS-Net: Conditional Atlas Generation and Brain Segmentation for Fetal
MRI
- Authors: Liu Li, Qiang Ma, Matthew Sinclair, Antonios Makropoulos, Joseph
Hajnal, A. David Edwards, Bernhard Kainz, Daniel Rueckert, Amir Alansary
- Abstract summary: We propose a novel network structure that can simultaneously generate conditional atlases and predict brain tissue segmentation.
The proposed method is trained and evaluated on 253 subjects from the developing Human Connectome Project.
- Score: 10.127399319119911
- License: http://creativecommons.org/publicdomain/zero/1.0/
- Abstract: Fetal Magnetic Resonance Imaging (MRI) is used in prenatal diagnosis and to
assess early brain development. Accurate segmentation of the different brain
tissues is a vital step in several brain analysis tasks, such as cortical
surface reconstruction and tissue thickness measurements. Fetal MRI scans,
however, are prone to motion artifacts that can affect the correctness of both
manual and automatic segmentation techniques. In this paper, we propose a novel
network structure that can simultaneously generate conditional atlases and
predict brain tissue segmentation, called CAS-Net. The conditional atlases
provide anatomical priors that can constrain the segmentation connectivity,
despite the heterogeneity of intensity values caused by motion or partial
volume effects. The proposed method is trained and evaluated on 253 subjects
from the developing Human Connectome Project (dHCP). The results demonstrate
that the proposed method can generate conditional age-specific atlas with sharp
boundary and shape variance. It also segment multi-category brain tissues for
fetal MRI with a high overall Dice similarity coefficient (DSC) of $85.2\%$ for
the selected 9 tissue labels.
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