Multi-modal Retinal Image Registration Using a Keypoint-Based Vessel
Structure Aligning Network
- URL: http://arxiv.org/abs/2207.10506v1
- Date: Thu, 21 Jul 2022 14:36:51 GMT
- Title: Multi-modal Retinal Image Registration Using a Keypoint-Based Vessel
Structure Aligning Network
- Authors: Aline Sindel, Bettina Hohberger, Andreas Maier, Vincent Christlein
- Abstract summary: We propose an end-to-end trainable deep learning method for multi-modal retinal image registration.
Our method extracts convolutional features from the vessel structure for keypoint detection and description.
The keypoint detection and description network and graph neural network are jointly trained in a self-supervised manner.
- Score: 9.988115865060589
- License: http://arxiv.org/licenses/nonexclusive-distrib/1.0/
- Abstract: In ophthalmological imaging, multiple imaging systems, such as color fundus,
infrared, fluorescein angiography, optical coherence tomography (OCT) or OCT
angiography, are often involved to make a diagnosis of retinal disease.
Multi-modal retinal registration techniques can assist ophthalmologists by
providing a pixel-based comparison of aligned vessel structures in images from
different modalities or acquisition times. To this end, we propose an
end-to-end trainable deep learning method for multi-modal retinal image
registration. Our method extracts convolutional features from the vessel
structure for keypoint detection and description and uses a graph neural
network for feature matching. The keypoint detection and description network
and graph neural network are jointly trained in a self-supervised manner using
synthetic multi-modal image pairs and are guided by synthetically sampled
ground truth homographies. Our method demonstrates higher registration accuracy
as competing methods for our synthetic retinal dataset and generalizes well for
our real macula dataset and a public fundus dataset.
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