Unsupervised sequence-to-sequence learning for automatic signal quality assessment in multi-channel electrical impedance-based hemodynamic monitoring

• URL: http://arxiv.org/abs/2305.09368v2
• Date: Wed, 17 May 2023 05:03:30 GMT
• Title: Unsupervised sequence-to-sequence learning for automatic signal quality assessment in multi-channel electrical impedance-based hemodynamic monitoring
• Authors: Chang Min Hyun, Tae-Geun Kim, Kyounghun Lee
• Abstract summary: This study proposes an unsupervised sequence-to-sequence learning approach that automatically assesses the motion-induced reliability of the cardiac volume signal (CVS) in hemodynamic monitoring. An encoder-decoder model is trained not only to self-reproduce an input sequence of the CVS but also to extrapolate the future in a parallel fashion. A motion-influenced CVS of low-quality is detected, based on the residual between the input sequence and its neural representation with a cut-off value determined from the two-sigma rule of thumb over the training set.
• Score: 0.6875312133832077
• License: http://creativecommons.org/licenses/by/4.0/
• Abstract: This study proposes an unsupervised sequence-to-sequence learning approach that automatically assesses the motion-induced reliability degradation of the cardiac volume signal (CVS) in multi-channel electrical impedance-based hemodynamic monitoring. The proposed method attempts to tackle shortcomings in existing learning-based assessment approaches, such as the requirement of manual annotation for motion influence and the lack of explicit mechanisms for realizing motion-induced abnormalities under contextual variations in CVS over time. By utilizing long-short term memory and variational auto-encoder structures, an encoder--decoder model is trained not only to self-reproduce an input sequence of the CVS but also to extrapolate the future in a parallel fashion. By doing so, the model can capture contextual knowledge lying in a temporal CVS sequence while being regularized to explore a general relationship over the entire time-series. A motion-influenced CVS of low-quality is detected, based on the residual between the input sequence and its neural representation with a cut--off value determined from the two-sigma rule of thumb over the training set. Our experimental observations validated two claims: (i) in the learning environment of label-absence, assessment performance is achievable at a competitive level to the supervised setting, and (ii) the contextual information across a time series of CVS is advantageous for effectively realizing motion-induced unrealistic distortions in signal amplitude and morphology. We also investigated the capability as a pseudo-labeling tool to minimize human-craft annotation by preemptively providing strong candidates for motion-induced anomalies. Empirical evidence has shown that machine-guided annotation can reduce inevitable human-errors during manual assessment while minimizing cumbersome and time-consuming processes.

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