Latent Disentanglement in Mesh Variational Autoencoders Improves the
Diagnosis of Craniofacial Syndromes and Aids Surgical Planning
- URL: http://arxiv.org/abs/2309.10825v1
- Date: Tue, 5 Sep 2023 13:16:53 GMT
- Title: Latent Disentanglement in Mesh Variational Autoencoders Improves the
Diagnosis of Craniofacial Syndromes and Aids Surgical Planning
- Authors: Simone Foti, Alexander J. Rickart, Bongjin Koo, Eimear O' Sullivan,
Lara S. van de Lande, Athanasios Papaioannou, Roman Khonsari, Danail
Stoyanov, N. u. Owase Jeelani, Silvia Schievano, David J. Dunaway, Matthew J.
Clarkson
- Abstract summary: We will discuss the application of the Swap Disentangled Variational Autoencoder with relevance to Crouzon, Apert and Muenke syndromes.
By manipulating specific parameters of the generative model, it is also possible to simulate the outcome of a range of craniofacial surgical procedures.
- Score: 42.017495658167334
- License: http://creativecommons.org/licenses/by-nc-nd/4.0/
- Abstract: The use of deep learning to undertake shape analysis of the complexities of
the human head holds great promise. However, there have traditionally been a
number of barriers to accurate modelling, especially when operating on both a
global and local level. In this work, we will discuss the application of the
Swap Disentangled Variational Autoencoder (SD-VAE) with relevance to Crouzon,
Apert and Muenke syndromes. Although syndrome classification is performed on
the entire mesh, it is also possible, for the first time, to analyse the
influence of each region of the head on the syndromic phenotype. By
manipulating specific parameters of the generative model, and producing
procedure-specific new shapes, it is also possible to simulate the outcome of a
range of craniofacial surgical procedures. This opens new avenues to advance
diagnosis, aids surgical planning and allows for the objective evaluation of
surgical outcomes.
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