TAGS: A Test-Time Generalist-Specialist Framework with Retrieval-Augmented Reasoning and Verification
- URL: http://arxiv.org/abs/2505.18283v1
- Date: Fri, 23 May 2025 18:28:59 GMT
- Title: TAGS: A Test-Time Generalist-Specialist Framework with Retrieval-Augmented Reasoning and Verification
- Abstract summary: We present TAGS, a test-time framework that combines a broadly capable exemplar with a domain-specific specialist to offer complementary perspectives.<n>TAGS achieves strong performance across nine MedQA benchmarks, boosting GPT-4o accuracy by 13.8%, DeepSeek-R1 by 16.8%, and improving a vanilla 7B model from 14.1% to 23.9%.
- Score: 27.918192794935255
- License: http://creativecommons.org/licenses/by/4.0/
- Abstract: Recent advances such as Chain-of-Thought prompting have significantly improved large language models (LLMs) in zero-shot medical reasoning. However, prompting-based methods often remain shallow and unstable, while fine-tuned medical LLMs suffer from poor generalization under distribution shifts and limited adaptability to unseen clinical scenarios. To address these limitations, we present TAGS, a test-time framework that combines a broadly capable generalist with a domain-specific specialist to offer complementary perspectives without any model fine-tuning or parameter updates. To support this generalist-specialist reasoning process, we introduce two auxiliary modules: a hierarchical retrieval mechanism that provides multi-scale exemplars by selecting examples based on both semantic and rationale-level similarity, and a reliability scorer that evaluates reasoning consistency to guide final answer aggregation. TAGS achieves strong performance across nine MedQA benchmarks, boosting GPT-4o accuracy by 13.8%, DeepSeek-R1 by 16.8%, and improving a vanilla 7B model from 14.1% to 23.9%. These results surpass several fine-tuned medical LLMs, without any parameter updates. The code will be available at https://github.com/JianghaoWu/TAGS.
Related papers
- Evaluating Small Open LLMs for Medical Question Answering: A Practical Framework [0.0]
Large language models (LLMs) in medical question answering demands more than high average accuracy.<n>Online health communities such as Reddit have become a primary source of medical information for millions of users.<n>We present a practical, open-source evaluation framework for assessing small, locally-deployable open-weight LLMs on medical question answering.
arXiv Detail & Related papers (2026-04-12T08:56:15Z) - When Chain-of-Thought Backfires: Evaluating Prompt Sensitivity in Medical Language Models [2.064612766965483]
We evaluate MedGemma (4B and 27B parameters) on MedMCQA (4,183 questions) and PubMedQA (1,000 questions)<n>Our experiments reveal several concerning findings.
arXiv Detail & Related papers (2026-03-26T23:04:20Z) - CORE-Seg: Reasoning-Driven Segmentation for Complex Lesions via Reinforcement Learning [48.77689764063103]
We introduce ComLesion-14K, the first diverse Chain-of-Thought benchmark for reasoning-driven complex lesion segmentation.<n>We propose CORE-Seg, an end-to-end framework integrating reasoning with segmentation through a Semantic-Guided Prompt Adapter.<n>Our Method achieves state-of-the-art results with a mean Dice of 37.06% (14.89% higher than the second-best baseline), while reducing the failure rate to 18.42%.
arXiv Detail & Related papers (2026-03-06T04:58:55Z) - A Multi-Agent Framework for Medical AI: Leveraging Fine-Tuned GPT, LLaMA, and DeepSeek R1 for Evidence-Based and Bias-Aware Clinical Query Processing [0.4349324020366305]
Large language models (LLMs) show promise for healthcare question answering, but clinical use is limited by weak verification, insufficient evidence grounding, and unreliable confidence signalling.<n>We propose a multi-agent medical QA framework that combines complementary LLMs with evidence retrieval, uncertainty estimation, and bias checks to improve answer reliability.
arXiv Detail & Related papers (2026-02-15T14:17:27Z) - STAR : Bridging Statistical and Agentic Reasoning for Large Model Performance Prediction [78.0692157478247]
We propose STAR, a framework that bridges data-driven STatistical expectations with knowledge-driven Agentic Reasoning.<n>We show that STAR consistently outperforms all baselines on both score-based and rank-based metrics.
arXiv Detail & Related papers (2026-02-12T16:30:07Z) - From Conflict to Consensus: Boosting Medical Reasoning via Multi-Round Agentic RAG [65.0203623486525]
Large Language Models (LLMs) exhibit high reasoning capacity in medical question-answering.<n>Their tendency to produce hallucinations and outdated knowledge poses critical risks in healthcare fields.<n>Existing methods rely on noisy token-level signals and lack the multi-round refinement required for complex reasoning.
arXiv Detail & Related papers (2026-02-06T08:25:30Z) - MedAD-R1: Eliciting Consistent Reasoning in Interpretible Medical Anomaly Detection via Consistency-Reinforced Policy Optimization [46.65200216642429]
We introduce MedAD-38K, the first large-scale, multi-modal, and multi-center benchmark for MedAD featuring diagnostic Chain-of-Thought (CoT) annotations alongside structured Visual Question-Answering (VQA) pairs.<n>Our proposed model, MedAD-R1, achieves state-of-the-art (SOTA) performance on the MedAD-38K benchmark, outperforming strong baselines by more than 10%.
arXiv Detail & Related papers (2026-02-01T07:56:10Z) - Beyond Overall Accuracy: A Psychometric Deep Dive into the Topic-Specific Medical Capabilities of 80 Large Language Models [6.362188639024662]
We introduce textscMedIRT, a rigorous evaluation framework grounded in Item Response Theory (IRT)<n>We prospectively gathered fresh responses from 80 diverse Large Language Models (LLMs) on a balanced, 1,100-question USMLE-aligned benchmark.<n>We estimate LLM's latent model ability jointly with question difficulty and discrimination, yielding more stable and nuanced performance rankings than accuracy alone.
arXiv Detail & Related papers (2025-09-29T02:06:13Z) - From Harm to Help: Turning Reasoning In-Context Demos into Assets for Reasoning LMs [58.02809208460186]
We revisit this paradox using high-quality traces from DeepSeek-R1 as demonstrations.<n>We find that adding more exemplars consistently degrades accuracy, even when demonstrations are optimal.<n>We introduce Insight-to-solve (I2S), a sequential test-time procedure that turns demonstrations into explicit, reusable insights.
arXiv Detail & Related papers (2025-09-27T08:59:31Z) - Eigen-1: Adaptive Multi-Agent Refinement with Monitor-Based RAG for Scientific Reasoning [53.45095336430027]
We develop a unified framework that combines implicit retrieval and structured collaboration.<n>On Humanity's Last Exam (HLE) Bio/Chem Gold, our framework achieves 48.3% accuracy.<n>Results on SuperGPQA and TRQA confirm robustness across domains.
arXiv Detail & Related papers (2025-09-25T14:05:55Z) - Decoupling Clinical and Class-Agnostic Features for Reliable Few-Shot Adaptation under Shift [12.373281238541296]
Medical vision-language models (VLMs) offer promise for clinical decision support, yet their reliability under distribution shifts remains a major concern for safe deployment.<n>We propose DRiFt, a structured feature decoupling framework that explicitly separates clinically relevant signals from task-agnostic noise.<n>Our approach improves in-distribution performance by +11.4% Top-1 accuracy and +3.3% Macro-F1 over prior prompt-based methods.
arXiv Detail & Related papers (2025-09-11T12:26:57Z) - RPRO: Ranked Preference Reinforcement Optimization for Enhancing Medical QA and Diagnostic Reasoning [5.493679122639688]
Medical question answering requires advanced reasoning that integrates domain knowledge with logical inference.<n>We propose Ranked Preference Reinforcement Optimization (RPRO), a novel framework that combines reinforcement learning with preference-driven reasoning refinement.
arXiv Detail & Related papers (2025-08-31T19:38:25Z) - When Punctuation Matters: A Large-Scale Comparison of Prompt Robustness Methods for LLMs [55.20230501807337]
We present the first systematic evaluation of 5 methods for improving prompt robustness within a unified experimental framework.<n>We benchmark these techniques on 8 models from Llama, Qwen and Gemma families across 52 tasks from Natural Instructions dataset.
arXiv Detail & Related papers (2025-08-15T10:32:50Z) - CompassVerifier: A Unified and Robust Verifier for LLMs Evaluation and Outcome Reward [50.97588334916863]
We develop CompassVerifier, an accurate and robust lightweight verifier model for evaluation and outcome reward.<n>It demonstrates multi-domain competency spanning math, knowledge, and diverse reasoning tasks, with the capability to process various answer types.<n>We introduce VerifierBench benchmark comprising model outputs collected from multiple data sources, augmented through manual analysis of metaerror patterns to enhance CompassVerifier.
arXiv Detail & Related papers (2025-08-05T17:55:24Z) - Automatic Fine-grained Segmentation-assisted Report Generation [3.6341072547314037]
We present ASaRG, an extension of the popular LLaVA architecture for report generation.<n>Our approach achieves a +0.89% performance gain in CE F1 score compared to the LLaVA baseline.<n>Our code will be made publicly available at a later date.
arXiv Detail & Related papers (2025-07-22T14:16:20Z) - Uncertainty-Driven Expert Control: Enhancing the Reliability of Medical Vision-Language Models [52.2001050216955]
Existing methods aim to enhance the performance of Medical Vision Language Model (MedVLM) by adjusting model structure, fine-tuning with high-quality data, or through preference fine-tuning.<n>We propose an expert-in-the-loop framework named Expert-Controlled-Free Guidance (Expert-CFG) to align MedVLM with clinical expertise without additional training.
arXiv Detail & Related papers (2025-07-12T09:03:30Z) - Reinforcing Video Reasoning with Focused Thinking [65.85683941058916]
We propose TW-GRPO, a novel framework that enhances visual reasoning with focused thinking and dense reward granularity.<n>Specifically, we employ a token weighting mechanism that prioritizes tokens with high informational density.<n>We also reformulate RL training by shifting from single-choice to multi-choice QA tasks.
arXiv Detail & Related papers (2025-05-30T15:42:19Z) - A Modular Approach for Clinical SLMs Driven by Synthetic Data with Pre-Instruction Tuning, Model Merging, and Clinical-Tasks Alignment [46.776978552161395]
Small language models (SLMs) offer a cost-effective alternative to large language models such as GPT-4.<n>SLMs offer a cost-effective alternative, but their limited capacity requires biomedical domain adaptation.<n>We propose a novel framework for adapting SLMs into high-performing clinical models.
arXiv Detail & Related papers (2025-05-15T21:40:21Z) - Can Reasoning LLMs Enhance Clinical Document Classification? [7.026393789313748]
Large Language Models (LLMs) offer promising improvements in accuracy and efficiency for this task.<n>This study evaluates the performance and consistency of eight LLMs; four reasoning (Qwen QWQ, Deepseek Reasoner, GPT o3 Mini, Gemini 2.0 Flash Thinking) and four non-reasoning (Llama 3.3, GPT 4o Mini, Gemini 2.0 Flash, Deepseek Chat)<n>Results showed that reasoning models outperformed non-reasoning models in accuracy (71% vs 68%) and F1 score (67% vs 60%)
arXiv Detail & Related papers (2025-04-10T18:00:27Z) - Benchmarking Chinese Medical LLMs: A Medbench-based Analysis of Performance Gaps and Hierarchical Optimization Strategies [11.0505830548286]
This study introduces a granular error taxonomy through systematic analysis of top 10 models on MedBench.<n> Evaluation of 10 leading models reveals vulnerabilities, despite achieving 0.86 accuracy in medical knowledge recall.<n>Our analysis uncovers systemic weaknesses in knowledge boundary enforcement and multi-step reasoning.
arXiv Detail & Related papers (2025-03-10T13:28:25Z) - Quantifying the Reasoning Abilities of LLMs on Real-world Clinical Cases [48.87360916431396]
We introduce MedR-Bench, a benchmarking dataset of 1,453 structured patient cases, annotated with reasoning references.<n>We propose a framework encompassing three critical examination recommendation, diagnostic decision-making, and treatment planning, simulating the entire patient care journey.<n>Using this benchmark, we evaluate five state-of-the-art reasoning LLMs, including DeepSeek-R1, OpenAI-o3-mini, and Gemini-2.0-Flash Thinking, etc.
arXiv Detail & Related papers (2025-03-06T18:35:39Z) - Structured Outputs Enable General-Purpose LLMs to be Medical Experts [50.02627258858336]
Large language models (LLMs) often struggle with open-ended medical questions.<n>We propose a novel approach utilizing structured medical reasoning.<n>Our approach achieves the highest Factuality Score of 85.8, surpassing fine-tuned models.
arXiv Detail & Related papers (2025-03-05T05:24:55Z) - ALoRE: Efficient Visual Adaptation via Aggregating Low Rank Experts [71.91042186338163]
ALoRE is a novel PETL method that reuses the hypercomplex parameterized space constructed by Kronecker product to Aggregate Low Rank Experts.<n>Thanks to the artful design, ALoRE maintains negligible extra parameters and can be effortlessly merged into the frozen backbone.
arXiv Detail & Related papers (2024-12-11T12:31:30Z) - SemioLLM: Evaluating Large Language Models for Diagnostic Reasoning from Unstructured Clinical Narratives in Epilepsy [45.2233252981348]
Large Language Models (LLMs) have been shown to encode clinical knowledge.<n>We present SemioLLM, an evaluation framework that benchmarks 6 state-of-the-art models.<n>We show that most LLMs are able to accurately and confidently generate probabilistic predictions of seizure onset zones in the brain.
arXiv Detail & Related papers (2024-07-03T11:02:12Z) - Self-Evaluation Guided Beam Search for Reasoning [61.523627290397556]
We introduce a stepwise self-evaluation mechanism to guide and calibrate the reasoning process of Large Language Model (LLM)
We propose a decoding algorithm integrating the self-evaluation guidance via beam search.
Our approach surpasses the corresponding Codex-backboned baselines in few-shot accuracy by $6.34%$, $9.56%$, and $5.46%$ on the GSM8K, AQuA, and StrategyQA.
arXiv Detail & Related papers (2023-05-01T02:37:59Z) - Holistic Evaluation of Language Models [183.94891340168175]
Language models (LMs) are becoming the foundation for almost all major language technologies, but their capabilities, limitations, and risks are not well understood.
We present Holistic Evaluation of Language Models (HELM) to improve the transparency of language models.
arXiv Detail & Related papers (2022-11-16T18:51:34Z)
This list is automatically generated from the titles and abstracts of the papers in this site.
This site does not guarantee the quality of this site (including all information) and is not responsible for any consequences.