Generalizable Blood Cell Detection via Unified Dataset and Faster R-CNN

• URL: http://arxiv.org/abs/2511.08465v1
• Date: Wed, 12 Nov 2025 02:00:12 GMT
• Title: Generalizable Blood Cell Detection via Unified Dataset and Faster R-CNN
• Authors: Siddharth Sahay,
• Abstract summary: This paper presents a comprehensive methodology and comparative performance analysis for the automated classification and object detection of peripheral blood cells.<n>Data pipeline was first developed to standardize and merge four public datasets into a unified resource.<n>State-of-the-art Faster R-CNN object detection framework was employed, leveraging a ResNet-50-FPN backbone.
• Score: 0.33842793760651557
• License: http://arxiv.org/licenses/nonexclusive-distrib/1.0/
• Abstract: This paper presents a comprehensive methodology and comparative performance analysis for the automated classification and object detection of peripheral blood cells (PBCs) in microscopic images. Addressing the critical challenge of data scarcity and heterogeneity, robust data pipeline was first developed to standardize and merge four public datasets (PBC, BCCD, Chula, Sickle Cell) into a unified resource. Then employed a state-of-the-art Faster R-CNN object detection framework, leveraging a ResNet-50-FPN backbone. Comparative training rigorously evaluated a randomly initialized baseline model (Regimen 1) against a Transfer Learning Regimen (Regimen 2), initialized with weights pre-trained on the Microsoft COCO dataset. The results demonstrate that the Transfer Learning approach achieved significantly faster convergence and superior stability, culminating in a final validation loss of 0.08666, a substantial improvement over the baseline. This validated methodology establishes a robust foundation for building high-accuracy, deployable systems for automated hematological diagnosis.

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