HULFSynth : An INR based Super-Resolution and Ultra Low-Field MRI Synthesis via Contrast factor estimation

• URL: http://arxiv.org/abs/2511.14897v1
• Date: Tue, 18 Nov 2025 20:36:24 GMT
• Title: HULFSynth : An INR based Super-Resolution and Ultra Low-Field MRI Synthesis via Contrast factor estimation
• Authors: Pranav Indrakanti, Ivor Simpson,
• Abstract summary: We present an unsupervised single image bidirectional Magnetic Resonance Image (MRI) synthesizer.<n>It synthesizes an Ultra-Low Field (ULF) like image from a High-Field (HF) magnitude image and vice-versa.<n>Our approach is inspired by the physics that drives contrast changes between HF and ULF MRIs.
• Score: 0.20434955508889785
• License: http://arxiv.org/licenses/nonexclusive-distrib/1.0/
• Abstract: We present an unsupervised single image bidirectional Magnetic Resonance Image (MRI) synthesizer that synthesizes an Ultra-Low Field (ULF) like image from a High-Field (HF) magnitude image and vice-versa. Unlike existing MRI synthesis models, our approach is inspired by the physics that drives contrast changes between HF and ULF MRIs. Our forward model simulates a HF to ULF transformation by estimating the tissue-type Signal-to-Noise ratio (SNR) values based on target contrast values. For the Super-Resolution task, we used an Implicit Neural Representation (INR) network to synthesize HF image by simultaneously predicting tissue-type segmentations and image intensity without observed HF data. The proposed method is evaluated using synthetic ULF-like data from generated from standard 3T T$_1$-weighted images for qualitative assessments and paired 3T-64mT T$_1$-weighted images for validation experiments. WM-GM contrast improved by 52% in synthetic ULF-like images and 37% in 64mT images. Sensitivity experiments demonstrated the robustness of our forward model to variations in target contrast, noise and initial seeding.

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