Efficient Vision Mamba for MRI Super-Resolution via Hybrid Selective Scanning

• URL: http://arxiv.org/abs/2512.19676v2
• Date: Thu, 25 Dec 2025 22:41:51 GMT
• Title: Efficient Vision Mamba for MRI Super-Resolution via Hybrid Selective Scanning
• Authors: Mojtaba Safari, Shansong Wang, Vanessa L Wildman, Mingzhe Hu, Zach Eidex, Chih-Wei Chang, Erik H Middlebrooks, Richard L. J Qiu, Pretesh Patel, Ashesh B. Jani, Hui Mao, Zhen Tian, Xiaofeng Yang,
• Abstract summary: Superresolution MRI can enhance resolution post-scan, yet deep learning methods face tradeoffs.<n>We propose a novel framework combining multi-head selective state-space models with a lightweight channel.<n>Model achieved superior performance with exceptional efficiency.
• Score: 5.1712742264130815
• License: http://creativecommons.org/licenses/by/4.0/
• Abstract: Background: High-resolution MRI is critical for diagnosis, but long acquisition times limit clinical use. Super-resolution (SR) can enhance resolution post-scan, yet existing deep learning methods face fidelity-efficiency trade-offs. Purpose: To develop a computationally efficient and accurate deep learning framework for MRI SR that preserves anatomical detail for clinical integration. Materials and Methods: We propose a novel SR framework combining multi-head selective state-space models (MHSSM) with a lightweight channel MLP. The model uses 2D patch extraction with hybrid scanning to capture long-range dependencies. Each MambaFormer block integrates MHSSM, depthwise convolutions, and gated channel mixing. Evaluation used 7T brain T1 MP2RAGE maps (n=142) and 1.5T prostate T2w MRI (n=334). Comparisons included Bicubic interpolation, GANs (CycleGAN, Pix2pix, SPSR), transformers (SwinIR), Mamba (MambaIR), and diffusion models (I2SB, Res-SRDiff). Results: Our model achieved superior performance with exceptional efficiency. For 7T brain data: SSIM=0.951+-0.021, PSNR=26.90+-1.41 dB, LPIPS=0.076+-0.022, GMSD=0.083+-0.017, significantly outperforming all baselines (p<0.001). For prostate data: SSIM=0.770+-0.049, PSNR=27.15+-2.19 dB, LPIPS=0.190+-0.095, GMSD=0.087+-0.013. The framework used only 0.9M parameters and 57 GFLOPs, reducing parameters by 99.8% and computation by 97.5% versus Res-SRDiff, while outperforming SwinIR and MambaIR in accuracy and efficiency. Conclusion: The proposed framework provides an efficient, accurate MRI SR solution, delivering enhanced anatomical detail across datasets. Its low computational demand and state-of-the-art performance show strong potential for clinical translation.

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