IRIS: An Intelligent Vision-Language System for Ocular Surface Diseases via Topic Tree and Scene-Driven VQA Generation
- URL: http://arxiv.org/abs/2607.04344v1
- Date: Sun, 05 Jul 2026 14:59:32 GMT
- Title: IRIS: An Intelligent Vision-Language System for Ocular Surface Diseases via Topic Tree and Scene-Driven VQA Generation
- Abstract summary: IRIS is an Intelligent Recognition and Interaction System tailored for fine-grained ocular surface diseases (OSDs) understanding via external eye photography.<n>To overcome the semantic shallowness of conventional image-caption pairs, we propose a synergistic data generation paradigm to explicitly inject clinical priors.<n>Our findings underscore that structured knowledge injection profoundly prevails over sheer parameter scaling, unlocking the potential for resource-efficient, expert-level AI deployment.
- Score: 2.9438135444211526
- License: http://arxiv.org/licenses/nonexclusive-distrib/1.0/
- Abstract: While Large Vision-Language Models (VLMs) demonstrate remarkable generic capabilities, their clinical reasoning in specialized domains like ocular surface diseases (OSDs) is severely hindered by a paucity of high-fidelity, multimodal instruction-tuning data. To dismantle this data bottleneck, we introduce IRIS, an Intelligent Recognition and Interaction System tailored for fine-grained OSD understanding via external eye photography. First, we curate IRIS-120K, the largest and most comprehensive OSD visual question-answering (VQA) dataset to date. Crucially, to overcome the semantic shallowness of conventional image-caption pairs, we propose a synergistic data generation paradigm to explicitly inject clinical priors. Our data engine operates via a dual-branch framework: 1) a Topic Finding Tree (TFT) that hierarchically anchors visual features to precise anatomical and pathological concepts, enforcing rigorous medical deduction logic; and 2) a Scene-driven strategy that synthesizes role-adaptive clinical dialogues to ensure pragmatic generalization. By explicitly aligning a compact 4B-parameter VLM on this structurally enriched corpus, IRIS achieves state-of-the-art performance, comprehensively outperforming both generalist and specialized medical VLMs with up to 34B parameters. Our findings underscore that structured knowledge injection profoundly prevails over sheer parameter scaling, unlocking the potential for resource-efficient, expert-level AI deployment on mobile edge devices for scalable OSD screening. Code, datasets, and model weights will be publicly released by this repo.
Related papers
- Unlocking Biological Workflows for Robust Protein-Text Question Answering: A Dual-Dimensional RAG Framework [60.82334952881798]
Protein-Text Question Answering (QA) is crucial for interpreting biological sequences through natural language.<n>We propose 2D-ProteinRAG, a novel framework that empowers Large Language Models (LLMs) to operate within the gold-standard biological research workflow.<n>We show that 2D-Protein consistently achieves state-of-the-art performance, outperforming fine-tuned baselines and other RAG methods.
arXiv Detail & Related papers (2026-05-17T05:03:24Z) - Graph-Augmented Topological Internalization with Dual-Stream Classifiers for Medical Report Generation [3.3887144970801555]
We propose a Graph-Augmented Dual-Stream Medical Report Generation with Topological Internalization, GDMRG.<n>Our framework introduces a Topological Knowledge Internalization module, TKI, which generates an explicit parameterized weight matrix based on global disease co-occurrence priors.<n>Experiments on the MIMIC-CXR dataset demonstrate that GDMRG achieves competitive clinical efficacy, CE, while maintaining natural language fluency.
arXiv Detail & Related papers (2026-05-04T09:17:27Z) - Deep Expert Injection for Anchoring Retinal VLMs with Domain-Specific Knowledge [66.67024684187915]
Large Vision Language Models (LVLMs) show immense potential for automated ophthalmic diagnosis.<n>Their clinical deployment is severely hindered by lacking domain-specific knowledge.<n>EyExIn is a framework designed to anchor retinal VLMs with expert knowledge via a Deep Expert Injection mechanism.
arXiv Detail & Related papers (2026-03-07T09:43:49Z) - Context-Aware Asymmetric Ensembling for Interpretable Retinopathy of Prematurity Screening via Active Query and Vascular Attention [1.8420107091891775]
Retinopathy of Prematurity (ROP) is among the major causes of preventable childhood blindness.<n>Current deep learning models depend heavily on large private datasets and passive multimodal fusion.<n>We propose the Context-Aware Asymmetric Ensemble Model (CAA Ensemble) that simulates clinical reasoning through two specialized streams.
arXiv Detail & Related papers (2026-02-05T02:06:26Z) - A Semantically Enhanced Generative Foundation Model Improves Pathological Image Synthesis [82.01597026329158]
We introduce a Correlation-Regulated Alignment Framework for Tissue Synthesis (CRAFTS) for pathology-specific text-to-image synthesis.<n>CRAFTS incorporates a novel alignment mechanism that suppresses semantic drift to ensure biological accuracy.<n>This model generates diverse pathological images spanning 30 cancer types, with quality rigorously validated by objective metrics and pathologist evaluations.
arXiv Detail & Related papers (2025-12-15T10:22:43Z) - DuPLUS: Dual-Prompt Vision-Language Framework for Universal Medical Image Segmentation and Prognosis [5.494301428436596]
We introduce DuPLUS, a deep learning framework for efficient multi-modal medical image analysis.<n>DuPLUS introduces a novel vision-language framework that leverages hierarchical semantic prompts for fine-grained control over the analysis task.<n>For segmentation, DuPLUS is able to generalize across three imaging modalities, ten different various medical datasets, encompassing more than 30 organs and tumor types.
arXiv Detail & Related papers (2025-10-03T20:01:00Z) - AIGI-Holmes: Towards Explainable and Generalizable AI-Generated Image Detection via Multimodal Large Language Models [78.08374249341514]
The rapid development of AI-generated content (AIGC) has led to the misuse of AI-generated images (AIGI) in spreading misinformation.<n>We introduce a large-scale and comprehensive dataset, Holmes-Set, which includes an instruction-tuning dataset with explanations on whether images are AI-generated.<n>Our work introduces an efficient data annotation method called the Multi-Expert Jury, enhancing data generation through structured MLLM explanations and quality control.<n>In addition, we propose Holmes Pipeline, a meticulously designed three-stage training framework comprising visual expert pre-training, supervised fine-tuning, and direct preference optimization
arXiv Detail & Related papers (2025-07-03T14:26:31Z) - Decentralized LoRA Augmented Transformer with Context-aware Multi-scale Feature Learning for Secured Eye Diagnosis [2.1358421658740214]
This paper proposes a novel Data efficient Image Transformer (DeiT) based framework that integrates context aware multiscale patch embedding, Low-Rank Adaptation (LoRA), knowledge distillation, and federated learning to address these challenges in a unified manner.<n>The proposed model effectively captures both local and global retinal features by leveraging multi scale patch representations with local and global attention mechanisms.
arXiv Detail & Related papers (2025-05-11T13:51:56Z) - EyecareGPT: Boosting Comprehensive Ophthalmology Understanding with Tailored Dataset, Benchmark and Model [51.66031028717933]
Medical Large Vision-Language Models (Med-LVLMs) demonstrate significant potential in healthcare.<n>Currently, intelligent ophthalmic diagnosis faces three major challenges: (i) Data; (ii) Benchmark; and (iii) Model.<n>We propose the Eyecare Kit, which tackles the aforementioned three key challenges with the tailored dataset, benchmark and model.
arXiv Detail & Related papers (2025-04-18T12:09:15Z) - Cross-modal Clinical Graph Transformer for Ophthalmic Report Generation [116.87918100031153]
We propose a Cross-modal clinical Graph Transformer (CGT) for ophthalmic report generation (ORG)
CGT injects clinical relation triples into the visual features as prior knowledge to drive the decoding procedure.
Experiments on the large-scale FFA-IR benchmark demonstrate that the proposed CGT is able to outperform previous benchmark methods.
arXiv Detail & Related papers (2022-06-04T13:16:30Z)
This list is automatically generated from the titles and abstracts of the papers in this site.
This site does not guarantee the quality of this site (including all information) and is not responsible for any consequences.