Unsupervised Local Discrimination for Medical Images
- URL: http://arxiv.org/abs/2108.09440v1
- Date: Sat, 21 Aug 2021 04:53:19 GMT
- Title: Unsupervised Local Discrimination for Medical Images
- Authors: Huai Chen, Renzhen Wang, Jieyu Li, Qing Peng, Deyu Meng and Lisheng
Wang
- Abstract summary: Contrastive representation learning is an effective method to alleviate the demand for expensive annotated data in medical image processing.
Recent work mainly based on instance-wise discrimination to learn global features, while neglect local details.
We propose a universal local discrmination framework to learn local discriminative features to effectively initialize medical models.
- Score: 35.14445357879895
- License: http://arxiv.org/licenses/nonexclusive-distrib/1.0/
- Abstract: Contrastive representation learning is an effective unsupervised method to
alleviate the demand for expensive annotated data in medical image processing.
Recent work mainly based on instance-wise discrimination to learn global
features, while neglect local details, which limit their application in
processing tiny anatomical structures, tissues and lesions. Therefore, we aim
to propose a universal local discrmination framework to learn local
discriminative features to effectively initialize medical models, meanwhile, we
systematacially investigate its practical medical applications. Specifically,
based on the common property of intra-modality structure similarity, i.e.
similar structures are shared among the same modality images, a systematic
local feature learning framework is proposed. Instead of making instance-wise
comparisons based on global embedding, our method makes pixel-wise embedding
and focuses on measuring similarity among patches and regions. The finer
contrastive rule makes the learnt representation more generalized for
segmentation tasks and outperform extensive state-of-the-art methods by wining
11 out of all 12 downstream tasks in color fundus and chest X-ray. Furthermore,
based on the property of inter-modality shape similarity, i.e. structures may
share similar shape although in different medical modalities, we joint
across-modality shape prior into region discrimination to realize unsupervised
segmentation. It shows the feaibility of segmenting target only based on shape
description from other modalities and inner pattern similarity provided by
region discrimination. Finally, we enhance the center-sensitive ability of
patch discrimination by introducing center-sensitive averaging to realize
one-shot landmark localization, this is an effective application for patch
discrimination.
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