Automatic Landmarks Correspondence Detection in Medical Images with an
Application to Deformable Image Registration
- URL: http://arxiv.org/abs/2109.02722v1
- Date: Mon, 6 Sep 2021 20:16:27 GMT
- Title: Automatic Landmarks Correspondence Detection in Medical Images with an
Application to Deformable Image Registration
- Authors: Monika Grewal, Jan Wiersma, Henrike Westerveld, Peter A. N. Bosman,
Tanja Alderliesten
- Abstract summary: DCNN-Match learns to predict landmark correspondences in 3D images in a self-supervised manner.
Results show significant improvement in DIR performance when landmark correspondences predicted by DCNN-Match were used in case of simulated as well as clinical deformations.
- Score: 0.0
- License: http://creativecommons.org/licenses/by-nc-nd/4.0/
- Abstract: Deformable Image Registration (DIR) can benefit from additional guidance
using corresponding landmarks in the images. However, the benefits thereof are
largely understudied, especially due to the lack of automatic detection methods
for corresponding landmarks in three-dimensional (3D) medical images. In this
work, we present a Deep Convolutional Neural Network (DCNN), called DCNN-Match,
that learns to predict landmark correspondences in 3D images in a
self-supervised manner. We explored five variants of DCNN-Match that use
different loss functions and tested DCNN-Match separately as well as in
combination with the open-source registration software Elastix to assess its
impact on a common DIR approach. We employed lower-abdominal Computed
Tomography (CT) scans from cervical cancer patients: 121 pelvic CT scan pairs
containing simulated elastic transformations and 11 pairs demonstrating
clinical deformations. Our results show significant improvement in DIR
performance when landmark correspondences predicted by DCNN-Match were used in
case of simulated as well as clinical deformations. We also observed that the
spatial distribution of the automatically identified landmarks and the
associated matching errors affect the extent of improvement in DIR. Finally,
DCNN-Match was found to generalize well to Magnetic Resonance Imaging (MRI)
scans without requiring retraining, indicating easy applicability to other
datasets.
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