En route to nanoscopic quantum optical imaging: counting emitters with
photon-number-resolving detectors
- URL: http://arxiv.org/abs/2110.03893v1
- Date: Fri, 8 Oct 2021 04:52:42 GMT
- Title: En route to nanoscopic quantum optical imaging: counting emitters with
photon-number-resolving detectors
- Authors: Shuo Li, Wenchao Li, Vladislav V. Yakovlev, Allison Kealy, Andrew D.
Greentree
- Abstract summary: Fundamental understanding of biological pathways requires minimally invasive nanoscopic optical resolution imaging.
Many approaches to high-resolution imaging rely on localization of single emitters, such as fluorescent molecule or quantum dot.
We show that quantum measurements of the number of photons emitted from an ensemble of emitters enable the determination of the number of emitters and the probability of emission.
- Score: 8.54443177764705
- License: http://arxiv.org/licenses/nonexclusive-distrib/1.0/
- Abstract: Fundamental understanding of biological pathways requires minimally invasive
nanoscopic optical resolution imaging. Many approaches to high-resolution
imaging rely on localization of single emitters, such as fluorescent molecule
or quantum dot. Exact determination of the number of such emitters in an
imaging volume is essential for a number of applications; however, in a
commonly employed intensity-based microscopy it is not possible to distinguish
individual emitters without initial knowledge of system parameters. Here we
explore how quantum measurements of the emitted photons using photon number
resolving detectors can be used to address this challenging task. In the
proposed new approach, the problem of counting emitters reduces to the task of
determining differences between the emitted photons and the Poisson limit. We
show that quantum measurements of the number of photons emitted from an
ensemble of emitters enable the determination of both the number of emitters
and the probability of emission. This method can be applied for any type of
emitters, including Raman and infrared emitters, which makes it a truly
universal way to achieve super-resolution optical imaging. The scaling laws of
this new approach are presented by the Cramer-Rao Lower Bounds and define the
extent this technique can be used for quantum optical imaging with nanoscopic
resolution.
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