Beyond Low Earth Orbit: Biomonitoring, Artificial Intelligence, and
  Precision Space Health
        - URL: http://arxiv.org/abs/2112.12554v1
 - Date: Wed, 22 Dec 2021 05:33:15 GMT
 - Title: Beyond Low Earth Orbit: Biomonitoring, Artificial Intelligence, and
  Precision Space Health
 - Authors: Ryan T. Scott (1), Erik L. Antonsen (2), Lauren M. Sanders (3), Jaden
  J.A. Hastings (4), Seung-min Park (5), Graham Mackintosh (6), Robert J.
  Reynolds (7), Adrienne L. Hoarfrost (8), Aenor Sawyer (9), Casey S. Greene
  (10), Benjamin S. Glicksberg (11), Corey A. Theriot (12 and 13), Daniel C.
  Berrios (1), Jack Miller (1), Joel Babdor (14), Richard Barker (15), Sergio
  E. Baranzini (16), Afshin Beheshti (1), Stuart Chalk (17), Guillermo M.
  Delgado-Aparicio (18), Melissa Haendel (19), Arif A. Hamid (20), Philip
  Heller (21), Daniel Jamieson (22), Katelyn J. Jarvis (9), John Kalantari
  (23), Kia Khezeli (23), Svetlana V. Komarova (24), Matthieu Komorowski (25),
  Prachi Kothiyal (26), Ashish Mahabal (27), Uri Manor (28), Hector Garcia
  Martin (29 and 30 and 31), Christopher E. Mason (4), Mona Matar (32), George
  I. Mias (33), Jerry G. Myers, Jr. (32), Charlotte Nelson (16), Jonathan
  Oribello (3), Patricia Parsons-Wingerter (34), R. K. Prabhu (35), Amina Ann
  Qutub (36), Jon Rask (37), Amanda Saravia-Butler (38), Suchi Saria (39 and
  40), Nitin Kumar Singh (41), Frank Soboczenski (42), Michael Snyder (43),
  Karthik Soman (16), David Van Valen (44), Kasthuri Venkateswaran (41), Liz
  Warren (45), Liz Worthey (46), Jason H. Yang (47), Marinka Zitnik (48),
  Sylvain V. Costes (49) ((1) KBR, Space Biosciences Division, NASA Ames
  Research Center, Moffett Field, CA, USA., (2) Department of Emergency
  Medicine, Center for Space Medicine, Baylor College of Medicine, Houston, TX,
  USA., (3) Blue Marble Space Institute of Science, Space Biosciences Division,
  NASA Ames Research Center, Moffett Field, CA, USA., (4) Department of
  Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USA., (5)
  Department of Urology, Department of Radiology, Stanford University School of
  Medicine, Stanford, CA, USA., (6) Bay Area Environmental Research Institute,
  NASA Ames Research Center, Moffett Field, CA, USA., (7) Mortality Research &
  Consulting, Inc., Houston, TX, USA., (8) Universities Space Research
  Association (USRA), Space Biosciences Division, NASA Ames Research Center,
  Moffett Field, CA, USA., (9) UC Space Health, Department of Orthopaedic
  Surgery, University of California, San Francisco, San Francisco, CA, USA.,
  (10) Center for Health AI, Department of Biochemistry and Molecular Genetics,
  University of Colorado School of Medicine, Anschutz Medical Campus, Aurora,
  CO, USA., (11) Hasso Plattner Institute for Digital Health at Mount Sinai,
  Department of Genetics and Genomic Sciences, Icahn School of Medicine at
  Mount Sinai, New York, NY, USA., (12) Department of Preventive Medicine and
  Community Health, UTMB, Galveston, TX, USA., (13) Human Health and
  Performance Directorate, NASA Johnson Space Center, Houston, TX, USA., (14)
  Department of Microbiology and Immunology, Department of Otolaryngology, Head
  and Neck Surgery, University of California San Francisco, San Francisco, CA,
  USA., (15) The Gilroy AstroBiology Research Group, The University of
  Wisconsin, Madison, Madison, WI, USA., (16) Weill Institute for
  Neurosciences, Department of Neurology, University of California San
  Francisco, San Francisco, CA, USA., (17) Department of Chemistry, University
  of North Florida, Jacksonville, FL, USA., (18) Data Science Analytics,
  Georgia Institute of Technology, Lima, Peru., (19) Center for Health AI,
  University of Colorado School of Medicine, Anschutz Medical Campus, Aurora,
  CO, USA., (20) Department of Neuroscience, University of Minnesota,
  Minneapolis, MN, USA., (21) Department of Computer Science, College of
  Science, San Jos\'e State University, San Jose, CA, USA., (22) Biorelate,
  Manchester, United Kingdom., (23) Center for Individualized Medicine,
  Department of Surgery, Department of Quantitative Health Sciences, Mayo
  Clinic, Rochester, MN, USA., (24) Faculty of Dental Medicine and Oral Health
  Sciences, McGill University, Montreal, Quebec, Canada., (25) Faculty of
  Medicine, Department of Surgery and Cancer, Imperial College London, London,
  United Kingdom., (26) SymbioSeq LLC, NASA Johnson Space Center, Ashburn, VA,
  USA., (27) Center for Data Driven Discovery, California Institute of
  Technology, Pasadena, CA, USA., (28) Waitt Advanced Biophotonics Center,
  Chan-Zuckerberg Imaging Scientist Fellow, Salk Institute for Biological
  Studies, La Jolla, CA, USA., (29) Biological Systems and Engineering
  Division, Lawrence Berkeley National Lab, Berkeley, CA, USA., (30) DOE Agile
  BioFoundry, Emeryville, CA, USA., (31) Joint BioEnergy Institute, Emeryville,
  CA, USA., (32) Human Research Program Cross-cutting Computational Modeling
  Project, NASA John H. Glenn Research Center, Cleveland, OH, USA., (33)
  Institute for Quantitative Health Science and Engineering, Department of
  Biochemistry and Molecular Biology, Michigan State University, East Lansing,
  MI, USA., (34) Low Exploration Gravity Technology, NASA John H. Glenn
  Research Center, Cleveland, OH, USA., (35) Universities Space Research
  Association (USRA), Human Research Program Cross-cutting Computational
  Modeling Project, NASA John H. Glenn Research Center, Cleveland, OH, USA.,
  (36) AI MATRIX Consortium, Department of Biomedical Engineering, University
  of Texas, San Antonio and UT Health Sciences, San Antonio, TX, USA., (37)
  Office of the Center Director, NASA Ames Research Center, Moffett Field, CA,
  USA., (38) Logyx, Space Biosciences Division, NASA Ames Research Center,
  Moffett Field, CA, USA., (39) Computer Science, Statistics, and Health
  Policy, Johns Hopkins University, Baltimore, MD, USA., (40) ML, AI and
  Healthcare Lab, Bayesian Health, New York, NY, USA., (41) Biotechnology and
  Planetary Protection Group, Jet Propulsion Laboratory, Pasadena, CA, USA.,
  (42) SPHES, Medical Faculty, King's College London, London, United Kingdom.,
  (43) Department of Genetics, Stanford School of Medicine, Stanford, CA, USA.,
  (44) Department of Biology, California Institute of Technology, Pasadena, CA,
  USA., (45) ISS National Laboratory, Center for the Advancement of Science in
  Space, Melbourne, FL, USA., (46) UAB Center for Computational Biology and
  Data Science, University of Alabama, Birmingham, Birmingham, AL, USA., (47)
  Center for Emerging and Re-Emerging Pathogens, Department of Microbiology,
  Biochemistry and Molecular Genetics, Rutgers New Jersey Medical School,
  Newark, NJ, USA., (48) Department of Biomedical Informatics, Harvard Medical
  School, Harvard Data Science, Broad Institute of MIT and Harvard, Harvard
  University, Boston, MA, USA., (49) Space Biosciences Division, NASA Ames
  Research Center, Moffett Field, CA, USA.)
 - Abstract summary: We propose an appropriately autonomous and intelligent Precision Space Health system.
It will monitor, aggregate, and assess biomedical statuses.
It will analyze and predict personalized adverse health outcomes.
 - Score: 0.8838373492847601
 - License: http://creativecommons.org/licenses/by/4.0/
 - Abstract:   Human space exploration beyond low Earth orbit will involve missions of
significant distance and duration. To effectively mitigate myriad space health
hazards, paradigm shifts in data and space health systems are necessary to
enable Earth-independence, rather than Earth-reliance. Promising developments
in the fields of artificial intelligence and machine learning for biology and
health can address these needs. We propose an appropriately autonomous and
intelligent Precision Space Health system that will monitor, aggregate, and
assess biomedical statuses; analyze and predict personalized adverse health
outcomes; adapt and respond to newly accumulated data; and provide preventive,
actionable, and timely insights to individual deep space crew members and
iterative decision support to their crew medical officer. Here we present a
summary of recommendations from a workshop organized by the National
Aeronautics and Space Administration, on future applications of artificial
intelligence in space biology and health. In the next decade, biomonitoring
technology, biomarker science, spacecraft hardware, intelligent software, and
streamlined data management must mature and be woven together into a Precision
Space Health system to enable humanity to thrive in deep space.
 
       
      
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