BlindHarmony: "Blind" Harmonization for MR Images via Flow model
- URL: http://arxiv.org/abs/2305.10732v2
- Date: Wed, 16 Aug 2023 10:39:12 GMT
- Title: BlindHarmony: "Blind" Harmonization for MR Images via Flow model
- Authors: Hwihun Jeong, Heejoon Byun, Dong Un Kang, and Jongho Lee
- Abstract summary: In MRI, images of the same contrast from the same subject can exhibit noticeable differences when acquired using different hardware, sequences, or scan parameters.
These differences create a domain gap that needs to be bridged by image harmonization.
Deep learning-based approaches have been proposed to achieve image harmonization.
We propose BlindHarmony, which utilizes only target domain data for training but still has the capability to harmonize images from unseen domains.
- Score: 1.765282368080009
- License: http://creativecommons.org/licenses/by/4.0/
- Abstract: In MRI, images of the same contrast (e.g., T$_1$) from the same subject can
exhibit noticeable differences when acquired using different hardware,
sequences, or scan parameters. These differences in images create a domain gap
that needs to be bridged by a step called image harmonization, to process the
images successfully using conventional or deep learning-based image analysis
(e.g., segmentation). Several methods, including deep learning-based
approaches, have been proposed to achieve image harmonization. However, they
often require datasets from multiple domains for deep learning training and may
still be unsuccessful when applied to images from unseen domains. To address
this limitation, we propose a novel concept called `Blind Harmonization', which
utilizes only target domain data for training but still has the capability to
harmonize images from unseen domains. For the implementation of blind
harmonization, we developed BlindHarmony using an unconditional flow model
trained on target domain data. The harmonized image is optimized to have a
correlation with the input source domain image while ensuring that the latent
vector of the flow model is close to the center of the Gaussian distribution.
BlindHarmony was evaluated on both simulated and real datasets and compared to
conventional methods. BlindHarmony demonstrated noticeable performance on both
datasets, highlighting its potential for future use in clinical settings. The
source code is available at: https://github.com/SNU-LIST/BlindHarmony
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