Towards Automatic Scoring of Spinal X-ray for Ankylosing Spondylitis
- URL: http://arxiv.org/abs/2308.05123v1
- Date: Tue, 8 Aug 2023 19:59:23 GMT
- Title: Towards Automatic Scoring of Spinal X-ray for Ankylosing Spondylitis
- Authors: Yuanhan Mo and Yao Chen and Aimee Readie and Gregory Ligozio and
Thibaud Coroller and Bart{\l}omiej W. Papie\.z
- Abstract summary: manually grading structural changes with the modified Stoke Ankylosing Spondylitis Spinal Score (mSASSS) on spinal X-ray imaging is costly and time-consuming.
We propose a 2-step auto-grading pipeline, called VertXGradeNet, to automatically predict mSASSS scores for the cervical and lumbar vertebral units (VUs) in X-ray spinal imaging.
- Score: 4.310687588548587
- License: http://creativecommons.org/licenses/by/4.0/
- Abstract: Manually grading structural changes with the modified Stoke Ankylosing
Spondylitis Spinal Score (mSASSS) on spinal X-ray imaging is costly and
time-consuming due to bone shape complexity and image quality variations. In
this study, we address this challenge by prototyping a 2-step auto-grading
pipeline, called VertXGradeNet, to automatically predict mSASSS scores for the
cervical and lumbar vertebral units (VUs) in X-ray spinal imaging. The
VertXGradeNet utilizes VUs generated by our previously developed VU extraction
pipeline (VertXNet) as input and predicts mSASSS based on those VUs.
VertXGradeNet was evaluated on an in-house dataset of lateral cervical and
lumbar X-ray images for axial spondylarthritis patients. Our results show that
VertXGradeNet can predict the mSASSS score for each VU when the data is limited
in quantity and imbalanced. Overall, it can achieve a balanced accuracy of 0.56
and 0.51 for 4 different mSASSS scores (i.e., a score of 0, 1, 2, 3) on two
test datasets. The accuracy of the presented method shows the potential to
streamline the spinal radiograph readings and therefore reduce the cost of
future clinical trials.
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