DRAK: Unlocking Molecular Insights with Domain-Specific Retrieval-Augmented Knowledge in LLMs

• URL: http://arxiv.org/abs/2406.18535v1
• Date: Mon, 4 Mar 2024 15:04:05 GMT
• Title: DRAK: Unlocking Molecular Insights with Domain-Specific Retrieval-Augmented Knowledge in LLMs
• Authors: Jinzhe Liu, Xiangsheng Huang, Zhuo Chen, Yin Fang,
• Abstract summary: Domain-specific Retrieval-Augmented Knowledge (DRAK) is a non-parametric knowledge injection framework for large language models. DRAK has developed profound expertise in the molecular domain and the capability to handle a broad spectrum of analysis tasks. Our code will be available soon.
• Score: 6.728130796437259
• License: http://arxiv.org/licenses/nonexclusive-distrib/1.0/
• Abstract: Large Language Models (LLMs) encounter challenges with the unique syntax of specific domains, such as biomolecules. Existing fine-tuning or modality alignment techniques struggle to bridge the domain knowledge gap and understand complex molecular data, limiting LLMs' progress in specialized fields. To overcome these limitations, we propose an expandable and adaptable non-parametric knowledge injection framework named Domain-specific Retrieval-Augmented Knowledge (DRAK), aimed at enhancing reasoning capabilities in specific domains. Utilizing knowledge-aware prompts and gold label-induced reasoning, DRAK has developed profound expertise in the molecular domain and the capability to handle a broad spectrum of analysis tasks. We evaluated two distinct forms of DRAK variants, proving that DRAK exceeds previous benchmarks on six molecular tasks within the Mol-Instructions dataset. Extensive experiments have underscored DRAK's formidable performance and its potential to unlock molecular insights, offering a unified paradigm for LLMs to tackle knowledge-intensive tasks in specific domains. Our code will be available soon.

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