Scalable Evaluation Framework for Foundation Models in Musculoskeletal MRI Bridging Computational Innovation with Clinical Utility

• URL: http://arxiv.org/abs/2501.13376v1
• Date: Thu, 23 Jan 2025 04:41:20 GMT
• Title: Scalable Evaluation Framework for Foundation Models in Musculoskeletal MRI Bridging Computational Innovation with Clinical Utility
• Authors: Gabrielle Hoyer, Michelle W Tong, Rupsa Bhattacharjee, Valentina Pedoia, Sharmila Majumdar,
• Abstract summary: This study introduces an evaluation framework for assessing the clinical impact and translatability of SAM, MedSAM, and SAM2. We tested these models across zero-shot and finetuned paradigms to assess their ability to process diverse anatomical structures and effectuate clinically reliable biomarkers.
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• Abstract: Foundation models hold transformative potential for medical imaging, but their clinical utility requires rigorous evaluation to address their strengths and limitations. This study introduces an evaluation framework for assessing the clinical impact and translatability of SAM, MedSAM, and SAM2, using musculoskeletal MRI as a case study. We tested these models across zero-shot and finetuned paradigms to assess their ability to process diverse anatomical structures and effectuate clinically reliable biomarkers, including cartilage thickness, muscle volume, and disc height. We engineered a modular pipeline emphasizing scalability, clinical relevance, and workflow integration, reducing manual effort and aligning validation with end-user expectations. Hierarchical modeling revealed how dataset mixing, anatomical complexity, and MRI acquisition parameters influence performance, providing insights into the role of imaging refinements in improving segmentation accuracy. This work demonstrates how clinically focused evaluations can connect computational advancements with tangible applications, creating a pathway for foundation models to address medical challenges. By emphasizing interdisciplinary collaboration and aligning technical innovation with clinical priorities, our framework provides a roadmap for advancing machine learning technologies into scalable and impactful biomedical solutions.

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