Variational U-Net with Local Alignment for Joint Tumor Extraction and Registration (VALOR-Net) of Breast MRI Data Acquired at Two Different Field Strengths
- URL: http://arxiv.org/abs/2501.13690v1
- Date: Thu, 23 Jan 2025 14:15:54 GMT
- Title: Variational U-Net with Local Alignment for Joint Tumor Extraction and Registration (VALOR-Net) of Breast MRI Data Acquired at Two Different Field Strengths
- Authors: Muhammad Shahkar Khan, Haider Ali, Laura Villazan Garcia, Noor Badshah, Siegfried Trattnig, Florian Schwarzhans, Ramona Woitek, Olgica Zaric,
- Abstract summary: Multidimensional breast MRI data might improve tumor diagnostics, characterization, and treatment planning.
Accurate alignment and delineation of images acquired at different field strengths such as 3T and 7T, remain challenging research tasks.
The proposed method may be feasible in providing joint tumor segmentation and registration of MRI data acquired at different field strengths.
- Score: 0.43163184307789293
- License:
- Abstract: Background: Multiparametric breast MRI data might improve tumor diagnostics, characterization, and treatment planning. Accurate alignment and delineation of images acquired at different field strengths such as 3T and 7T, remain challenging research tasks. Purpose: To address alignment challenges and enable consistent tumor segmentation across different MRI field strengths. Study type: Retrospective. Subjects: Nine female subjects with breast tumors were involved: six histologically proven invasive ductal carcinomas (IDC) and three fibroadenomas. Field strength/sequence: Imaging was performed at 3T and 7T scanners using post-contrast T1-weighted three-dimensional time-resolved angiography with stochastic trajectories (TWIST) sequence. Assessments: The method's performance for joint image registration and tumor segmentation was evaluated using several quantitative metrics, including signal-to-noise ratio (PSNR), structural similarity index (SSIM), normalized cross-correlation (NCC), Dice coefficient, F1 score, and relative sum of squared differences (rel SSD). Statistical tests: The Pearson correlation coefficient was used to test the relationship between the registration and segmentation metrics. Results: When calculated for each subject individually, the PSNR was in a range from 27.5 to 34.5 dB, and the SSIM was from 82.6 to 92.8%. The model achieved an NCC from 96.4 to 99.3% and a Dice coefficient of 62.9 to 95.3%. The F1 score was between 55.4 and 93.2% and the rel SSD was in the range of 2.0 and 7.5%. The segmentation metrics Dice and F1 Score are highly correlated (0.995), while a moderate correlation between NCC and SSIM (0.681) was found for registration. Data conclusion: Initial results demonstrate that the proposed method may be feasible in providing joint tumor segmentation and registration of MRI data acquired at different field strengths.
Related papers
- Multi-centric AI Model for Unruptured Intracranial Aneurysm Detection and Volumetric Segmentation in 3D TOF-MRI [6.397650339311053]
We developed an open-source nnU-Net-based AI model for combined detection and segmentation of unruptured intracranial aneurysms (UICA) in 3D TOF-MRI.
Four distinct training datasets were created, and the nnU-Net framework was used for model development.
The primary model showed 85% sensitivity and 0.23 FP/case rate, outperforming the ADAM-challenge winner (61%) and a nnU-Net trained on ADAM data (51%) in sensitivity.
arXiv Detail & Related papers (2024-08-30T08:57:04Z) - Deep learning-based brain segmentation model performance validation with clinical radiotherapy CT [0.0]
This study validates the SynthSeg robust brain segmentation model on computed tomography (CT)
Brain segmentations from CT and MRI were obtained with SynthSeg model, a component of the Freesurfer imaging suite.
CT performance is lower than MRI based on the integrated QC scores, but low-quality segmentations can be excluded with QC-based thresholding.
arXiv Detail & Related papers (2024-06-25T09:56:30Z) - TotalSegmentator MRI: Sequence-Independent Segmentation of 59 Anatomical Structures in MR images [62.53931644063323]
In this study we extended the capabilities of TotalSegmentator to MR images.
We trained an nnU-Net segmentation algorithm on this dataset and calculated similarity coefficients (Dice) to evaluate the model's performance.
The model significantly outperformed two other publicly available segmentation models (Dice score 0.824 versus 0.762; p0.001 and 0.762 versus 0.542; p)
arXiv Detail & Related papers (2024-05-29T20:15:54Z) - Analysis of the BraTS 2023 Intracranial Meningioma Segmentation Challenge [44.586530244472655]
We describe the design and results from the BraTS 2023 Intracranial Meningioma Challenge.
The BraTS Meningioma Challenge differed from prior BraTS Glioma challenges in that it focused on meningiomas.
The top ranked team had a lesion-wise median dice similarity coefficient (DSC) of 0.976, 0.976, and 0.964 for enhancing tumor, tumor core, and whole tumor.
arXiv Detail & Related papers (2024-05-16T03:23:57Z) - TRUSTED: The Paired 3D Transabdominal Ultrasound and CT Human Data for
Kidney Segmentation and Registration Research [42.90853857929316]
Inter-modal image registration (IMIR) and image segmentation with abdominal Ultrasound (US) data has many important clinical applications.
We propose TRUSTED (the Tridimensional Ultra Sound TomodEnsitometrie dataset), comprising paired transabdominal 3DUS and CT kidney images from 48 human patients.
arXiv Detail & Related papers (2023-10-19T11:09:50Z) - EMT-NET: Efficient multitask network for computer-aided diagnosis of
breast cancer [58.720142291102135]
We propose an efficient and light-weighted learning architecture to classify and segment breast tumors simultaneously.
We incorporate a segmentation task into a tumor classification network, which makes the backbone network learn representations focused on tumor regions.
The accuracy, sensitivity, and specificity of tumor classification is 88.6%, 94.1%, and 85.3%, respectively.
arXiv Detail & Related papers (2022-01-13T05:24:40Z) - Accurate Prostate Cancer Detection and Segmentation on Biparametric MRI
using Non-local Mask R-CNN with Histopathological Ground Truth [0.0]
We developed deep machine learning models to improve the detection and segmentation of intraprostatic lesions on bp-MRI.
Models were trained using MRI-based delineations with prostatectomy-based delineations.
With prostatectomy-based delineations, the non-local Mask R-CNN with fine-tuning and self-training significantly improved all evaluation metrics.
arXiv Detail & Related papers (2020-10-28T21:07:09Z) - Automatic lesion detection, segmentation and characterization via 3D
multiscale morphological sifting in breast MRI [3.4400216692203998]
We present a breast MRI CAD system that can handle 4D multimodal breast MRI data, and integrate lesion detection, segmentation and characterization with no user intervention.
The proposed CAD system consists of three major stages: region candidate generation, feature extraction and region candidate classification.
Compared with previously proposed systems evaluated on the same breast MRI dataset, the proposed CAD system achieves a favourable performance in breast lesion detection and characterization.
arXiv Detail & Related papers (2020-07-07T04:39:13Z) - Segmentation of the Myocardium on Late-Gadolinium Enhanced MRI based on
2.5 D Residual Squeeze and Excitation Deep Learning Model [55.09533240649176]
The aim of this work is to develop an accurate automatic segmentation method based on deep learning models for the myocardial borders on LGE-MRI.
A total number of 320 exams (with a mean number of 6 slices per exam) were used for training and 28 exams used for testing.
The performance analysis of the proposed ensemble model in the basal and middle slices was similar as compared to intra-observer study and slightly lower at apical slices.
arXiv Detail & Related papers (2020-05-27T20:44:38Z) - A multicenter study on radiomic features from T$_2$-weighted images of a
customized MR pelvic phantom setting the basis for robust radiomic models in
clinics [47.187609203210705]
2D and 3D T$$-weighted images of a pelvic phantom were acquired on three scanners.
repeatability and repositioning of radiomic features were assessed.
arXiv Detail & Related papers (2020-05-14T09:24:48Z)
This list is automatically generated from the titles and abstracts of the papers in this site.
This site does not guarantee the quality of this site (including all information) and is not responsible for any consequences.