Individualised Treatment Effects Estimation with Composite Treatments and Composite Outcomes
- URL: http://arxiv.org/abs/2502.08282v1
- Date: Wed, 12 Feb 2025 10:41:21 GMT
- Title: Individualised Treatment Effects Estimation with Composite Treatments and Composite Outcomes
- Authors: Vinod Kumar Chauhan, Lei Clifton, Gaurav Nigam, David A. Clifton,
- Abstract summary: Estimating individualised treatment effect (ITE) remains a fundamental problem in causal inference.
Previous work in causal machine learning for ITE estimation is limited to simple settings, like single treatments and single outcomes.
We propose a novel and innovative hypernetwork-based approach, called emphH-Learner, to solve ITE estimation under composite treatments and composite outcomes.
- Score: 13.925793826373706
- License:
- Abstract: Estimating individualised treatment effect (ITE) -- that is the causal effect of a set of variables (also called exposures, treatments, actions, policies, or interventions), referred to as \textit{composite treatments}, on a set of outcome variables of interest, referred to as \textit{composite outcomes}, for a unit from observational data -- remains a fundamental problem in causal inference with applications across disciplines, such as healthcare, economics, education, social science, marketing, and computer science. Previous work in causal machine learning for ITE estimation is limited to simple settings, like single treatments and single outcomes. This hinders their use in complex real-world scenarios; for example, consider studying the effect of different ICU interventions, such as beta-blockers and statins for a patient admitted for heart surgery, on different outcomes of interest such as atrial fibrillation and in-hospital mortality. The limited research into composite treatments and outcomes is primarily due to data scarcity for all treatments and outcomes. To address the above challenges, we propose a novel and innovative hypernetwork-based approach, called \emph{H-Learner}, to solve ITE estimation under composite treatments and composite outcomes, which tackles the data scarcity issue by dynamically sharing information across treatments and outcomes. Our empirical analysis with binary and arbitrary composite treatments and outcomes demonstrates the effectiveness of the proposed approach compared to existing methods.
Related papers
- Higher-Order Causal Message Passing for Experimentation with Complex Interference [6.092214762701847]
We introduce a new class of estimators based on causal message-passing, specifically designed for settings with pervasive, unknown interference.
Our estimator draws on information from the sample mean and variance of unit outcomes and treatments over time, enabling efficient use of observed data.
arXiv Detail & Related papers (2024-11-01T18:00:51Z) - The Blessings of Multiple Treatments and Outcomes in Treatment Effect
Estimation [53.81860494566915]
Existing studies leveraged proxy variables or multiple treatments to adjust for confounding bias.
In many real-world scenarios, there is greater interest in studying the effects on multiple outcomes.
We show that parallel studies of multiple outcomes involved in this setting can assist each other in causal identification.
arXiv Detail & Related papers (2023-09-29T14:33:48Z) - A Flexible Framework for Incorporating Patient Preferences Into
Q-Learning [1.2891210250935146]
In real-world healthcare problems, there are often multiple competing outcomes of interest, such as treatment efficacy and side effect severity.
statistical methods for estimating dynamic treatment regimes (DTRs) usually assume a single outcome of interest.
This includes restrictions to a single time point and two outcomes, the inability to incorporate self-reported patient preferences and limited theoretical guarantees.
arXiv Detail & Related papers (2023-07-22T08:58:07Z) - Benchmarking Heterogeneous Treatment Effect Models through the Lens of
Interpretability [82.29775890542967]
Estimating personalized effects of treatments is a complex, yet pervasive problem.
Recent developments in the machine learning literature on heterogeneous treatment effect estimation gave rise to many sophisticated, but opaque, tools.
We use post-hoc feature importance methods to identify features that influence the model's predictions.
arXiv Detail & Related papers (2022-06-16T17:59:05Z) - Disentangled Counterfactual Recurrent Networks for Treatment Effect
Inference over Time [71.30985926640659]
We introduce the Disentangled Counterfactual Recurrent Network (DCRN), a sequence-to-sequence architecture that estimates treatment outcomes over time.
With an architecture that is completely inspired by the causal structure of treatment influence over time, we advance forecast accuracy and disease understanding.
We demonstrate that DCRN outperforms current state-of-the-art methods in forecasting treatment responses, on both real and simulated data.
arXiv Detail & Related papers (2021-12-07T16:40:28Z) - SurvITE: Learning Heterogeneous Treatment Effects from Time-to-Event
Data [83.50281440043241]
We study the problem of inferring heterogeneous treatment effects from time-to-event data.
We propose a novel deep learning method for treatment-specific hazard estimation based on balancing representations.
arXiv Detail & Related papers (2021-10-26T20:13:17Z) - Learning Decomposed Representation for Counterfactual Inference [53.36586760485262]
The fundamental problem in treatment effect estimation from observational data is confounder identification and balancing.
Most of the previous methods realized confounder balancing by treating all observed pre-treatment variables as confounders, ignoring further identifying confounders and non-confounders.
We propose a synergistic learning framework to 1) identify confounders by learning representations of both confounders and non-confounders, 2) balance confounder with sample re-weighting technique, and simultaneously 3) estimate the treatment effect in observational studies via counterfactual inference.
arXiv Detail & Related papers (2020-06-12T09:50:42Z) - Generalization Bounds and Representation Learning for Estimation of
Potential Outcomes and Causal Effects [61.03579766573421]
We study estimation of individual-level causal effects, such as a single patient's response to alternative medication.
We devise representation learning algorithms that minimize our bound, by regularizing the representation's induced treatment group distance.
We extend these algorithms to simultaneously learn a weighted representation to further reduce treatment group distances.
arXiv Detail & Related papers (2020-01-21T10:16:33Z)
This list is automatically generated from the titles and abstracts of the papers in this site.
This site does not guarantee the quality of this site (including all information) and is not responsible for any consequences.