How We Won the ISLES'24 Challenge by Preprocessing

• URL: http://arxiv.org/abs/2505.18424v2
• Date: Wed, 28 May 2025 22:02:21 GMT
• Title: How We Won the ISLES'24 Challenge by Preprocessing
• Authors: Tianyi Ren, Juampablo E. Heras Rivera, Hitender Oswal, Yutong Pan, William Henry, Sophie Walters, Mehmet Kurt,
• Abstract summary: Supervised deep learning methods have emerged as the leading solution for stroke lesion segmentation.<n>The ISLES'24 challenge addresses this need by providing longitudinal stroke imaging data.<n>Our winning solution shows that a carefully designed preprocessing pipeline is beneficial for accurate segmentation.
• Score: 0.1675245825272646
• License: http://creativecommons.org/licenses/by/4.0/
• Abstract: Stroke is among the top three causes of death worldwide, and accurate identification of stroke lesion boundaries is critical for diagnosis and treatment. Supervised deep learning methods have emerged as the leading solution for stroke lesion segmentation but require large, diverse, and annotated datasets. The ISLES'24 challenge addresses this need by providing longitudinal stroke imaging data, including CT scans taken on arrival to the hospital and follow-up MRI taken 2-9 days from initial arrival, with annotations derived from follow-up MRI. Importantly, models submitted to the ISLES'24 challenge are evaluated using only CT inputs, requiring prediction of lesion progression that may not be visible in CT scans for segmentation. Our winning solution shows that a carefully designed preprocessing pipeline including deep-learning-based skull stripping and custom intensity windowing is beneficial for accurate segmentation. Combined with a standard large residual nnU-Net architecture for segmentation, this approach achieves a mean test Dice of 28.5 with a standard deviation of 21.27.

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