GraphTreeGen: Subtree-Centric Approach to Efficient and Supervised Graph Generation
- URL: http://arxiv.org/abs/2508.09710v1
- Date: Wed, 13 Aug 2025 11:02:38 GMT
- Title: GraphTreeGen: Subtree-Centric Approach to Efficient and Supervised Graph Generation
- Authors: Yitong Luo, Islem Rekik,
- Abstract summary: GraphTreeGen (GTG) is a subtree-centric generative framework for efficient, accurate connectome synthesis.<n>GTG decomposes each connectome into entropy-guided k-hop trees capturing informative local structure.<n>Its modular design enables extensions to connectome super-resolution and cross-modality synthesis.
- Score: 6.138671548064356
- License: http://creativecommons.org/licenses/by-nc-sa/4.0/
- Abstract: Brain connectomes, representing neural connectivity as graphs, are crucial for understanding brain organization but costly and time-consuming to acquire, motivating generative approaches. Recent advances in graph generative modeling offer a data-driven alternative, enabling synthetic connectome generation and reducing dependence on large neuroimaging datasets. However, current models face key limitations: (i) compressing the whole graph into a single latent code (e.g., VGAEs) blurs fine-grained local motifs; (ii) relying on rich node attributes rarely available in connectomes reduces reconstruction quality; (iii) edge-centric models emphasize topology but overlook accurate edge-weight prediction, harming quantitative fidelity; and (iv) computationally expensive designs (e.g., edge-conditioned convolutions) impose high memory demands, limiting scalability. We propose GraphTreeGen (GTG), a subtree-centric generative framework for efficient, accurate connectome synthesis. GTG decomposes each connectome into entropy-guided k-hop trees capturing informative local structure, encoded by a shared GCN. A bipartite message-passing layer fuses subtree embeddings with global node features, while a dual-branch decoder jointly predicts edge existence and weights to reconstruct the adjacency matrix. GTG outperforms state-of-the-art baselines in self-supervised tasks and remains competitive in supervised settings, delivering higher structural fidelity and more precise weights with far less memory. Its modular design enables extensions to connectome super-resolution and cross-modality synthesis. Code: https://github.com/basiralab/GTG/
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