Rethinking Intracranial Aneurysm Vessel Segmentation: A Perspective from Computational Fluid Dynamics Applications

• URL: http://arxiv.org/abs/2512.01319v1
• Date: Mon, 01 Dec 2025 06:23:07 GMT
• Title: Rethinking Intracranial Aneurysm Vessel Segmentation: A Perspective from Computational Fluid Dynamics Applications
• Authors: Feiyang Xiao, Yichi Zhang, Xigui Li, Yuanye Zhou, Chen Jiang, Xin Guo, Limei Han, Yuxin Li, Fengping Zhu, Yuan Cheng,
• Abstract summary: The precise segmentation of intracranial aneurysms and their parent vessels (IA-Vessel) is a critical step for hemodynamic analyses.<n>We present the first comprehensive, multi-center collection comprising 641 3D MRA images with 587 annotations of aneurysms and IA-Vessels.
• Score: 22.729240391465634
• License: http://creativecommons.org/licenses/by-nc-nd/4.0/
• Abstract: The precise segmentation of intracranial aneurysms and their parent vessels (IA-Vessel) is a critical step for hemodynamic analyses, which mainly depends on computational fluid dynamics (CFD). However, current segmentation methods predominantly focus on image-based evaluation metrics, often neglecting their practical effectiveness in subsequent CFD applications. To address this deficiency, we present the Intracranial Aneurysm Vessel Segmentation (IAVS) dataset, the first comprehensive, multi-center collection comprising 641 3D MRA images with 587 annotations of aneurysms and IA-Vessels. In addition to image-mask pairs, IAVS dataset includes detailed hemodynamic analysis outcomes, addressing the limitations of existing datasets that neglect topological integrity and CFD applicability. To facilitate the development and evaluation of clinically relevant techniques, we construct two evaluation benchmarks including global localization of aneurysms (Stage I) and fine-grained segmentation of IA-Vessel (Stage II) and develop a simple and effective two-stage framework, which can be used as a out-of-the-box method and strong baseline. For comprehensive evaluation of applicability of segmentation results, we establish a standardized CFD applicability evaluation system that enables the automated and consistent conversion of segmentation masks into CFD models, offering an applicability-focused assessment of segmentation outcomes. The dataset, code, and model will be public available at https://github.com/AbsoluteResonance/IAVS.

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