Demo: Generative AI helps Radiotherapy Planning with User Preference

• URL: http://arxiv.org/abs/2512.08996v1
• Date: Mon, 08 Dec 2025 16:49:21 GMT
• Title: Demo: Generative AI helps Radiotherapy Planning with User Preference
• Authors: Riqiang Gao, Simon Arberet, Martin Kraus, Han Liu, Wilko FAR Verbakel, Dorin Comaniciu, Florin-Cristian Ghesu, Ali Kamen,
• Abstract summary: We introduce a novel generative model that predicts 3D dose distributions based solely on user-defined preference flavors.<n>These preferences enable planners to prioritize specific trade-offs between organs-at-risk (OARs) and planning target volumes (PTVs)
• Score: 8.699769678493807
• License: http://arxiv.org/licenses/nonexclusive-distrib/1.0/
• Abstract: Radiotherapy planning is a highly complex process that often varies significantly across institutions and individual planners. Most existing deep learning approaches for 3D dose prediction rely on reference plans as ground truth during training, which can inadvertently bias models toward specific planning styles or institutional preferences. In this study, we introduce a novel generative model that predicts 3D dose distributions based solely on user-defined preference flavors. These customizable preferences enable planners to prioritize specific trade-offs between organs-at-risk (OARs) and planning target volumes (PTVs), offering greater flexibility and personalization. Designed for seamless integration with clinical treatment planning systems, our approach assists users in generating high-quality plans efficiently. Comparative evaluations demonstrate that our method can surpasses the Varian RapidPlan model in both adaptability and plan quality in some scenarios.

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