Attention-Based Deep Learning for Early Parkinson's Disease Detection with Tabular Biomedical Data
- URL: http://arxiv.org/abs/2602.07933v1
- Date: Sun, 08 Feb 2026 12:03:02 GMT
- Title: Attention-Based Deep Learning for Early Parkinson's Disease Detection with Tabular Biomedical Data
- Authors: Olamide Samuel Oseni, Ibraheem Omotolani Obanla, Toheeb Aduramomi Jimoh,
- Abstract summary: Early and accurate detection of Parkinson's disease (PD) remains a critical challenge in medical diagnostics.<n>Traditional machine learning (ML) models, though widely applied to PD detection, often rely on extensive feature engineering and struggle to capture complex feature interactions.<n>We present a comparative evaluation of four classification models: Multi-Layer Perceptron (MLP), Gradient Boosting, TabNet, and SAINT.
- Score: 0.0
- License: http://creativecommons.org/licenses/by/4.0/
- Abstract: Early and accurate detection of Parkinson's disease (PD) remains a critical challenge in medical diagnostics due to the subtlety of early-stage symptoms and the complex, non-linear relationships inherent in biomedical data. Traditional machine learning (ML) models, though widely applied to PD detection, often rely on extensive feature engineering and struggle to capture complex feature interactions. This study investigates the effectiveness of attention-based deep learning models for early PD detection using tabular biomedical data. We present a comparative evaluation of four classification models: Multi-Layer Perceptron (MLP), Gradient Boosting, TabNet, and SAINT, using a benchmark dataset from the UCI Machine Learning Repository consisting of biomedical voice measurements from PD patients and healthy controls. Experimental results show that SAINT consistently outperformed all baseline models across multiple evaluation metrics, achieving a weighted precision of 0.98, weighted recall of 0.97, weighted F1-score of 0.97, a Matthews Correlation Coefficient (MCC) of 0.9990, and the highest Area Under the ROC Curve (AUC-ROC). TabNet and MLP demonstrated competitive performance, while Gradient Boosting yielded the lowest overall scores. The superior performance of SAINT is attributed to its dual attention mechanism, which effectively models feature interactions within and across samples. These findings demonstrate the diagnostic potential of attention-based deep learning architectures for early Parkinson's disease detection and highlight the importance of dynamic feature representation in clinical prediction tasks.
Related papers
- Investigating the Impact of Histopathological Foundation Models on Regressive Prediction of Homologous Recombination Deficiency [52.50039435394964]
We systematically evaluate foundation models for regression-based tasks.<n>We extract patch-level features from whole slide images (WSI) using five state-of-the-art foundation models.<n>Models are trained to predict continuous HRD scores based on these extracted features across breast, endometrial, and lung cancer cohorts.
arXiv Detail & Related papers (2026-01-29T14:06:50Z) - Residual GRU+MHSA: A Lightweight Hybrid Recurrent Attention Model for Cardiovascular Disease Detection [1.267904597444312]
We propose Residual GRU with Multi-Head Self-Attention, a compact deep learning architecture for clinical records.<n>We evaluate the model on the UCI Heart Disease dataset using 5-fold stratified cross-validation.<n>The proposed model achieves an accuracy of 0.861, macro-F1 of 0.860, ROC-AUC of 0.908, and PR-AUC of 0.904, outperforming all baselines.
arXiv Detail & Related papers (2025-12-16T16:33:59Z) - The use of vocal biomarkers in the detection of Parkinson's disease: a robust statistical performance comparison of classic machine learning models [1.3538255028226323]
Parkinson's disease (PD) is a progressive neurodegenerative disorder that, in addition to directly impairing functional mobility, is frequently associated with vocal impairments.<n>The use of vocal biomarkers to support the early diagnosis of PD presents a non-invasive, low-cost, and accessible alternative in clinical settings.<n>This study consistently evaluated the effectiveness of a Deep Neural Network (DNN) in distinguishing individuals with PD from healthy controls.
arXiv Detail & Related papers (2025-11-20T23:43:38Z) - Bridging Accuracy and Interpretability: Deep Learning with XAI for Breast Cancer Detection [0.0]
We present an interpretable deep learning framework for the early detection of breast cancer using quantitative features extracted from digitized fine needle aspirate (FNA) images of breast masses.<n>Our deep neural network, using ReLU activations, the Adam visualizations, and a binary cross-entropy loss, delivers state-of-the-art classification performance.
arXiv Detail & Related papers (2025-10-18T07:47:26Z) - Clinical NLP with Attention-Based Deep Learning for Multi-Disease Prediction [44.0876796031468]
This paper addresses the challenges posed by the unstructured nature and high-dimensional semantic complexity of electronic health record texts.<n>A deep learning method based on attention mechanisms is proposed to achieve unified modeling for information extraction and multi-label disease prediction.
arXiv Detail & Related papers (2025-07-02T07:45:22Z) - Predicting Length of Stay in Neurological ICU Patients Using Classical Machine Learning and Neural Network Models: A Benchmark Study on MIMIC-IV [49.1574468325115]
This study explores multiple ML approaches for predicting LOS in ICU specifically for the patients with neurological diseases based on the MIMIC-IV dataset.<n>The evaluated models include classic ML algorithms (K-Nearest Neighbors, Random Forest, XGBoost and CatBoost) and Neural Networks (LSTM, BERT and Temporal Fusion Transformer)
arXiv Detail & Related papers (2025-05-23T14:06:42Z) - Urinary Tract Infection Detection in Digital Remote Monitoring: Strategies for Managing Participant-Specific Prediction Complexity [43.108040967674185]
Urinary tract infections (UTIs) are a significant health concern, particularly for people living with dementia (PLWD)<n>This study builds on previous work that utilised machine learning (ML) to detect UTIs in PLWD.
arXiv Detail & Related papers (2025-02-18T12:01:55Z) - Distinguishing Parkinson's Patients Using Voice-Based Feature Extraction and Classification [0.0]
This study focuses on differentiating individuals with Parkinson's disease from healthy controls through the extraction and classification of speech features.<n>The accuracy of our 3-layer artificial neural network architecture was also compared with classical machine learning algorithms.
arXiv Detail & Related papers (2025-01-24T10:44:16Z) - Machine Learning for ALSFRS-R Score Prediction: Making Sense of the Sensor Data [44.99833362998488]
Amyotrophic Lateral Sclerosis (ALS) is a rapidly progressive neurodegenerative disease that presents individuals with limited treatment options.
The present investigation, spearheaded by the iDPP@CLEF 2024 challenge, focuses on utilizing sensor-derived data obtained through an app.
arXiv Detail & Related papers (2024-07-10T19:17:23Z) - AXIAL: Attention-based eXplainability for Interpretable Alzheimer's Localized Diagnosis using 2D CNNs on 3D MRI brain scans [43.06293430764841]
This study presents an innovative method for Alzheimer's disease diagnosis using 3D MRI designed to enhance the explainability of model decisions.
Our approach adopts a soft attention mechanism, enabling 2D CNNs to extract volumetric representations.
With voxel-level precision, our method identified which specific areas are being paid attention to, identifying these predominant brain regions.
arXiv Detail & Related papers (2024-07-02T16:44:00Z) - Alzheimer's disease detection in PSG signals [2.8691549050152965]
Alzheimers disease (AD) and sleep disorders exhibit a close association, where disruptions in sleep patterns often precede the onset of early-stage AD.
This study delves into the potential of utilizing sleep-related electroencephalography (EEG) signals for the early detection of AD.
Our primary focus is on exploring semi-supervised Deep Learning techniques for the classification of EEG signals due to the limited data availability.
arXiv Detail & Related papers (2024-04-04T15:56:23Z)
This list is automatically generated from the titles and abstracts of the papers in this site.
This site does not guarantee the quality of this site (including all information) and is not responsible for any consequences.