Generative Synthetic Data for Causal Inference: Pitfalls, Remedies, and Opportunities
- URL: http://arxiv.org/abs/2604.23904v1
- Date: Sun, 26 Apr 2026 22:38:23 GMT
- Title: Generative Synthetic Data for Causal Inference: Pitfalls, Remedies, and Opportunities
- Abstract summary: Synthetic data offers a promising tool for privacy-preserving data release, augmentation, and simulation.<n>But its use in causal inference requires preserving more than predictive fidelity.<n>We show that fully generative tabular synthesizers, including GAN- and LLM-based models, can achieve strong train-on-synthetic-test-on-real performance.
- Score: 4.144744763257738
- License: http://creativecommons.org/licenses/by/4.0/
- Abstract: Synthetic data offers a promising tool for privacy-preserving data release, augmentation, and simulation, but its use in causal inference requires preserving more than predictive fidelity. We show that fully generative tabular synthesizers, including GAN- and LLM-based models, can achieve strong train-on-synthetic-test-on-real performance while substantially distorting causal estimands such as the average treatment effect (ATE). We formalize this failure through sensitivity and tradeoff results showing that ATE preservation requires control of both the generated covariate law and the treatment-effect contrast in the outcome regression. Motivated by this observation, we propose a hybrid synthetic-data framework that generates covariates separately from the treatment and outcome mechanisms, using distance-to-closest-record diagnostics to monitor covariate synthesis and separately learned nuisance models to construct (W, A, Y) triplets. We further study targeted synthetic augmentation for practical positivity problems and characterize when added overlap support helps by improving conditional-effect estimation more than it shifts the covariate distribution. Finally, we develop a synthetic simulation engine for pre-analysis estimator evaluation, enabling finite-sample comparison of OR, IPW, AIPW, and TMLE under realistic covariate structure. Across experiments, hybrid synthetic data substantially improve ATE preservation relative to fully generative baselines and provide a practical diagnostic tool for robust causal analysis.
Related papers
- SynPre-FL: Synthetic data-driven pretraining integrated Federated Learning training framework [11.908618960989008]
We propose a unified framework combining high-fidelity synthetic EHR generation with synthetic-pretrained FL for robust prediction under non-IID conditions.<n>A latent autoencoder-diffusion model generates privacy-preserving synthetic cohorts, which are used to warm-start federated training.<n>Post-hoc calibration and federated-safe explainability support reliable and interpretable risk estimates.
arXiv Detail & Related papers (2026-07-21T19:12:48Z) - Joint Model and Data Sparsification via the Marginal Likelihood [53.29070892356214]
We propose jointly learning individual feature and sample relevancies, enabling simultaneous model and data sparsification.<n>This symmetric pruning of model and data offers a natural extension that preserves conjugacy.<n> Empirical results across diverse regression tasks affirm that a joint ARD approach consistently yields both sparse and robust prediction models.
arXiv Detail & Related papers (2026-05-28T13:26:53Z) - CausalWrap: Model-Agnostic Causal Constraint Wrappers for Tabular Synthetic Data [4.08271266107383]
CausalWrap is a model-agnostic wrapper that injects partial causal knowledge into any pretrained base generator.<n>CW learns a lightweight, differentiable post-hoc correction map applied to samples from the base generator.<n>CW improves causal fidelity across diverse base generators.
arXiv Detail & Related papers (2026-03-02T15:59:46Z) - A Technical Exploration of Causal Inference with Hybrid LLM Synthetic Data [3.121656940390038]
Large Language Models (LLMs) offer a flexible means to generate synthetic data.<n>Existing approaches often fail to preserve key causal parameters such as the average treatment effect (ATE)
arXiv Detail & Related papers (2025-10-31T23:34:44Z) - Improving the Generation and Evaluation of Synthetic Data for Downstream Medical Causal Inference [89.5628648718851]
Causal inference is essential for developing and evaluating medical interventions.<n>Real-world medical datasets are often difficult to access due to regulatory barriers.<n>We present STEAM: a novel method for generating Synthetic data for Treatment Effect Analysis in Medicine.
arXiv Detail & Related papers (2025-10-21T16:16:00Z) - Beyond Real Data: Synthetic Data through the Lens of Regularization [9.459299281438074]
Synthetic data can improve generalization when real data is scarce, but excessive reliance may introduce distributional mismatches that degrade performance.<n>We present a learning-theoretic framework to quantify the trade-off between synthetic and real data.
arXiv Detail & Related papers (2025-10-09T11:33:09Z) - Valid Inference with Imperfect Synthetic Data [39.10587411316875]
We introduce a new estimator based on generalized method of moments.<n>We find that interactions between the moment residuals of synthetic data and those of real data can greatly improve estimates of the target parameter.
arXiv Detail & Related papers (2025-08-08T18:32:52Z) - A Theoretical Perspective: How to Prevent Model Collapse in Self-consuming Training Loops [55.07063067759609]
High-quality data is essential for training large generative models, yet the vast reservoir of real data available online has become nearly depleted.<n>Models increasingly generate their own data for further training, forming Self-consuming Training Loops (STLs)<n>Some models degrade or even collapse, while others successfully avoid these failures, leaving a significant gap in theoretical understanding.
arXiv Detail & Related papers (2025-02-26T06:18:13Z) - Unveiling the Flaws: Exploring Imperfections in Synthetic Data and Mitigation Strategies for Large Language Models [89.88010750772413]
Synthetic data has been proposed as a solution to address the issue of high-quality data scarcity in the training of large language models (LLMs)
Our work delves into these specific flaws associated with question-answer (Q-A) pairs, a prevalent type of synthetic data, and presents a method based on unlearning techniques to mitigate these flaws.
Our work has yielded key insights into the effective use of synthetic data, aiming to promote more robust and efficient LLM training.
arXiv Detail & Related papers (2024-06-18T08:38:59Z) - Efficient adjustment for complex covariates: Gaining efficiency with
DOPE [56.537164957672715]
We propose a framework that accommodates adjustment for any subset of information expressed by the covariates.
Based on our theoretical results, we propose the Debiased Outcome-adapted Propensity Estorimator (DOPE) for efficient estimation of the average treatment effect (ATE)
Our results show that the DOPE provides an efficient and robust methodology for ATE estimation in various observational settings.
arXiv Detail & Related papers (2024-02-20T13:02:51Z) - CATE Estimation With Potential Outcome Imputation From Local Regression [24.97657507206549]
We propose a model-agnostic data augmentation method for Conditional Average Treatment Effect estimation.<n>Inspired by this idea, we propose a contrastive learning approach that reliably imputes missing potential outcomes.<n>We provide both theoretical guarantees and extensive numerical studies demonstrating the effectiveness of our approach.
arXiv Detail & Related papers (2023-11-07T00:36:51Z) - Autoregressive Score Matching [113.4502004812927]
We propose autoregressive conditional score models (AR-CSM) where we parameterize the joint distribution in terms of the derivatives of univariable log-conditionals (scores)
For AR-CSM models, this divergence between data and model distributions can be computed and optimized efficiently, requiring no expensive sampling or adversarial training.
We show with extensive experimental results that it can be applied to density estimation on synthetic data, image generation, image denoising, and training latent variable models with implicit encoders.
arXiv Detail & Related papers (2020-10-24T07:01:24Z)
This list is automatically generated from the titles and abstracts of the papers in this site.
This site does not guarantee the quality of this site (including all information) and is not responsible for any consequences.