PVminerLLM2: Improving Structured Extraction of Patient Voice via Preference Optimization
- URL: http://arxiv.org/abs/2606.16074v1
- Date: Mon, 15 Jun 2026 00:18:47 GMT
- Title: PVminerLLM2: Improving Structured Extraction of Patient Voice via Preference Optimization
- Abstract summary: Patient-generated text contains critical information on patients' lived experiences, social context, and care engagement.<n>Prior work introduced the PV-Miner benchmark and PVMinerLLM models for structured extraction.<n>We present PVminerLLM2, an improved set of LLMs for structured patient voice extraction.
- Score: 0.19582799051022884
- License: http://creativecommons.org/licenses/by/4.0/
- Abstract: Motivation: Patient-generated text contains critical information on patients' lived experiences, social context, and care engagement, but remains largely unstructured, limiting its use in patient-centered outcomes research. Prior work introduced the PV-Miner benchmark and PVMinerLLM models for structured extraction. However, supervised fine-tuning (SFT) alone struggles with rare, fine-grained, and unevenly distributed errors, particularly in token-critical structured outputs. Results: We present PVminerLLM2, an improved set of LLMs for structured patient voice extraction that applies preference optimization to address token-critical errors beyond the reach of supervised fine-tuning. Our method introduces (i) a preference objective with token-level gated stabilization term that prevents degradation of absolute token likelihood under preference optimization, and (ii) confusion-aware preference pair construction to better capture low-separation distinctions. We further incorporate token-importance weighting and inverse-frequency reweighing to address token imbalance and class skew. Across multiple model sizes, PVMinerLLM2 consistently outperforms strong baselines, achieving gains of up to 4.43% (Code), 3.50% (Sub-code), and 1.55% (Span), and outperforms baseline LLM trained with existing preference optimization methods. Availability and Implementation: The supplementary material, code, evaluation scripts, and trained models for PVminerLLM2 are publicly available at: https://github.com/Data-Mining-Lab-Yale/PVminerLLM2
Related papers
- Be Your Own Teacher: Steering Protein Language Models via Unsupervised Reward Optimization [85.4863852505905]
We introduce unsupervised reward optimization of protein language models (PLMs)<n>Our key insight is that task-agnostic rewards, which combine intrinsic model uncertainty with semantic consistency informed by protein representation models, exhibit strong correlation with controllability measures across base models and temperature regimes.<n>Our framework provides a scalable pathway toward controllable biomolecular design in settings where labeled preferences or experimental feedback are scarce or unavailable.
arXiv Detail & Related papers (2026-06-17T11:42:01Z) - Scaffold-Conditioned Preference Triplets for Controllable Molecular Optimization with Large Language Models [32.68069719676566]
We introduce textbfScaffold-Conditioned Preference Triplets ( SCPT), a pipeline that constructs similarity-constrained triplets $langletextscaffold, textbetter, textworserangle$ via scaffold alignment and chemistry-driven filters for validity, synthesizability, and meaningful property gains.<n>Compared with representative non-LLM molecular optimization methods, SCPT-trained LLMs are better suited to scaffold-constrained and multi-objective optimization.
arXiv Detail & Related papers (2026-04-14T06:38:07Z) - Margin Adaptive DPO: Leveraging Reward Model for Granular Control in Preference Optimization [0.0]
Margin-Adaptive Direct Preference Optimization provides a stable, data-preserving, and instance-level solution.<n>We provide a comprehensive theoretical analysis, proving that MADPO has a well-behaved optimization landscape.<n>It achieves performance gains of up to +33.3% on High Quality data and +10.5% on Low Quality data over the next-best method.
arXiv Detail & Related papers (2025-10-06T20:09:37Z) - Modality-Balancing Preference Optimization of Large Multimodal Models by Adversarial Negative Mining [75.14823970163685]
We propose a novel preference learning framework, Modality-Balancing Preference Optimization (MBPO), to address the modality imbalance in LMMs.<n>MBPO constructs a more effective offline preference dataset by generating hard negatives, i.e., rejected responses misled by LLM biases.<n>It can enhance LMM performance on challenging vision-language tasks and effectively reduce hallucinations.
arXiv Detail & Related papers (2025-05-20T03:59:05Z) - Dynamic Noise Preference Optimization for LLM Self-Improvement via Synthetic Data [51.62162460809116]
We introduce Dynamic Noise Preference Optimization (DNPO) to ensure consistent improvements across iterations.<n>In experiments with Zephyr-7B, DNPO consistently outperforms existing methods, showing an average performance boost of 2.6%.<n> DNPO shows a significant improvement in model-generated data quality, with a 29.4% win-loss rate gap compared to the baseline in GPT-4 evaluations.
arXiv Detail & Related papers (2025-02-08T01:20:09Z) - EACO: Enhancing Alignment in Multimodal LLMs via Critical Observation [58.546205554954454]
We propose Enhancing Alignment in MLLMs via Critical Observation (EACO)<n>EACO aligns MLLMs by self-generated preference data using only 5k images economically.<n>EACO reduces the overall hallucinations by 65.6% on HallusionBench and improves the reasoning ability by 21.8% on MME-Cognition.
arXiv Detail & Related papers (2024-12-06T09:59:47Z) - Self-supervised Preference Optimization: Enhance Your Language Model with Preference Degree Awareness [27.43137305486112]
We propose a novel Self-supervised Preference Optimization (SPO) framework, which constructs a self-supervised preference degree loss combined with the alignment loss.
The results demonstrate that SPO can be seamlessly integrated with existing preference optimization methods to achieve state-of-the-art performance.
arXiv Detail & Related papers (2024-09-26T12:37:26Z) - Self-Evolutionary Large Language Models through Uncertainty-Enhanced Preference Optimization [9.618391485742968]
Iterative preference optimization has recently become one of the de-facto training paradigms for large language models (LLMs)
We present an uncertainty-enhanced textbfPreference textbfOptimization framework to make the LLM self-evolve with reliable feedback.
Our framework substantially alleviates the noisy problem and improves the performance of iterative preference optimization.
arXiv Detail & Related papers (2024-09-17T14:05:58Z) - Aligning Large Language Models via Fine-grained Supervision [20.35000061196631]
Pre-trained large-scale language models (LLMs) excel at producing coherent articles, yet their outputs may be untruthful, toxic, or fail to align with user expectations.
Current approaches focus on using reinforcement learning with human feedback to improve model alignment.
We propose a method to enhance LLM alignment through fine-grained token-level supervision.
arXiv Detail & Related papers (2024-06-04T20:21:45Z) - Self-Augmented Preference Optimization: Off-Policy Paradigms for Language Model Alignment [104.18002641195442]
We introduce Self-Augmented Preference Optimization (SAPO), an effective and scalable training paradigm that does not require existing paired data.
Building on the self-play concept, which autonomously generates negative responses, we further incorporate an off-policy learning pipeline to enhance data exploration and exploitation.
arXiv Detail & Related papers (2024-05-31T14:21:04Z) - Sparse MoEs meet Efficient Ensembles [49.313497379189315]
We study the interplay of two popular classes of such models: ensembles of neural networks and sparse mixture of experts (sparse MoEs)
We present Efficient Ensemble of Experts (E$3$), a scalable and simple ensemble of sparse MoEs that takes the best of both classes of models, while using up to 45% fewer FLOPs than a deep ensemble.
arXiv Detail & Related papers (2021-10-07T11:58:35Z)
This list is automatically generated from the titles and abstracts of the papers in this site.
This site does not guarantee the quality of this site (including all information) and is not responsible for any consequences.