KANEx: Translating Kolmogorov-Arnold Networks' Interpretability to Medical Explainability
- URL: http://arxiv.org/abs/2607.24730v1
- Date: Mon, 27 Jul 2026 17:57:02 GMT
- Title: KANEx: Translating Kolmogorov-Arnold Networks' Interpretability to Medical Explainability
- Abstract summary: Computer vision models have become highly effective for medical applications, yet their black-box nature continues to undermine clinician trust.<n>We investigate whether this architectural transparency can be leveraged to produce more trustworthy explanations.<n>We introduce KANEx, the first ever framework that leverages the symbolic transparency of KANs to ground VLM reasoning.
- Score: 4.64163085848251
- License: http://creativecommons.org/licenses/by/4.0/
- Abstract: Computer vision models have become highly effective for medical applications, yet their black-box nature continues to undermine clinician trust. In clinical workflows, chest X-ray classifiers are increasingly paired with Vision-Language Models (VLMs) to generate natural-language explanations. However, these systems add linguistic fluency without addressing the underlying opacity of the visual model. With the emergence of Kolmogorov-Arnold Networks (KANs), whose spline-based components provide inherently interpretable functional units, we investigate whether this architectural transparency can be leveraged to produce more trustworthy textual explanations. We introduce KANEx, the first ever framework that leverages the symbolic transparency of KANs to ground VLM reasoning. This interpretability also made it possible to design KAN-Map, a novel heatmap generation method derived directly from KAN models rather than gradient approximations. We feed these grounded contexts into downstream VLMs for enhanced explainability. Benchmarked on the MIMIC-CXR dataset, we demonstrate that KAN-based architectures with ResNet/ViT baselines demonstrate improved semantic similarity while producing significantly more faithful saliency maps. KAN architectures improve visual localization and downstream reasoning quality by 10%. Our findings suggest that grounding linguistic explanations and visual attributions in mathematically interpretable units is a necessary step toward trustworthy medical AI.
Related papers
- Concept-Grounded Reasoning with Prompt-Driven Localization for Interpretable Structured Report Generation [66.62662330558906]
CORAL is a multimodal framework that integrates spatial grounding and concept-level supervision into a unified reasoning process.<n>CORAL employs a prompt-driven medical segmentation model to localize lesions and predicts multi-class clinical attributes through a Concept Bottleneck module.<n>Experiments on BUS-CoT and IU X-ray datasets demonstrate consistent improvements in diagnostic accuracy, concept consistency, and report quality over strong general-purpose and medical MLLMs.
arXiv Detail & Related papers (2026-09-14T10:21:23Z) - Concept-Enhanced Multimodal RAG: Towards Interpretable and Accurate Radiology Report Generation [12.226029763256962]
Radiology Report Generation through Vision-Language Models (VLMs) promises to reduce documentation burden, improve reporting consistency, and accelerate clinical adoption.<n>Existing research treats interpretability and accuracy as separate objectives, with concept-based explainability techniques focusing primarily on transparency.<n>We present Concept-Enhanced Multimodal RAG (CEMRAG), a unified framework that decomposes visual representations into interpretable clinical concepts.
arXiv Detail & Related papers (2026-02-17T15:18:07Z) - S-Chain: Structured Visual Chain-of-Thought For Medicine [81.97605645734741]
We introduce S-Chain, the first large-scale dataset of 12,000 expert-annotated medical images with bounding boxes and structured visual CoT (SV-CoT)<n>The dataset further supports 16 languages, totaling over 700k VQA pairs for broad multilingual applicability.<n>S-Chain establishes a new benchmark for grounded medical reasoning and paves the way toward more trustworthy and explainable medical vision-language models.
arXiv Detail & Related papers (2025-10-26T15:57:14Z) - XBench: A Comprehensive Benchmark for Visual-Language Explanations in Chest Radiography [6.447908430647854]
We present the first systematic benchmark for evaluating cross-modal interpretability in chest X-rays.<n>We generate visual explanations using cross-attention and similarity-based localization maps.<n>We quantitatively assess their alignment with radiologist-annotated regions across multiple pathologies.
arXiv Detail & Related papers (2025-10-22T13:52:19Z) - RAU: Reference-based Anatomical Understanding with Vision Language Models [26.06602931463068]
We introduce RAU, a framework for reference-based anatomical understanding with vision-language models (VLMs)<n>We first show that a VLM learns to identify anatomical regions through relative spatial reasoning between reference and target images.<n>Next, we demonstrate that the VLM-derived spatial cues can be seamlessly integrated with the fine-grained segmentation capability of SAM2.
arXiv Detail & Related papers (2025-09-26T14:32:03Z) - Interpretable Clinical Classification with Kolgomorov-Arnold Networks [70.72819760172744]
Kolmogorov-Arnold Networks (KANs) offer intrinsic interpretability through transparent, symbolic representations.<n>KANs support built-in patient-level insights, intuitive visualizations, and nearest-patient retrieval.<n>These results position KANs as a promising step toward trustworthy AI that clinicians can understand, audit, and act upon.
arXiv Detail & Related papers (2025-09-20T17:21:58Z) - Improving Network Interpretability via Explanation Consistency Evaluation [56.14036428778861]
We propose a framework that acquires more explainable activation heatmaps and simultaneously increase the model performance.
Specifically, our framework introduces a new metric, i.e., explanation consistency, to reweight the training samples adaptively in model learning.
Our framework then promotes the model learning by paying closer attention to those training samples with a high difference in explanations.
arXiv Detail & Related papers (2024-08-08T17:20:08Z) - Contrastive Learning with Counterfactual Explanations for Radiology Report Generation [83.30609465252441]
We propose a textbfCountertextbfFactual textbfExplanations-based framework (CoFE) for radiology report generation.
Counterfactual explanations serve as a potent tool for understanding how decisions made by algorithms can be changed by asking what if'' scenarios.
Experiments on two benchmarks demonstrate that leveraging the counterfactual explanations enables CoFE to generate semantically coherent and factually complete reports.
arXiv Detail & Related papers (2024-07-19T17:24:25Z) - U-KAN Makes Strong Backbone for Medical Image Segmentation and Generation [48.40120035775506]
Kolmogorov-Arnold Networks (KANs) reshape the neural network learning via the stack of non-linear learnable activation functions.
We investigate, modify and re-design the established U-Net pipeline by integrating the dedicated KAN layers on the tokenized intermediate representation, termed U-KAN.
We further delved into the potential of U-KAN as an alternative U-Net noise predictor in diffusion models, demonstrating its applicability in generating task-oriented model architectures.
arXiv Detail & Related papers (2024-06-05T04:13:03Z) - Dynamic Inference with Neural Interpreters [72.90231306252007]
We present Neural Interpreters, an architecture that factorizes inference in a self-attention network as a system of modules.
inputs to the model are routed through a sequence of functions in a way that is end-to-end learned.
We show that Neural Interpreters perform on par with the vision transformer using fewer parameters, while being transferrable to a new task in a sample efficient manner.
arXiv Detail & Related papers (2021-10-12T23:22:45Z)
This list is automatically generated from the titles and abstracts of the papers in this site.
This site does not guarantee the quality of this site (including all information) and is not responsible for any consequences.