DoFE: Domain-oriented Feature Embedding for Generalizable Fundus Image
Segmentation on Unseen Datasets
- URL: http://arxiv.org/abs/2010.06208v1
- Date: Tue, 13 Oct 2020 07:28:39 GMT
- Title: DoFE: Domain-oriented Feature Embedding for Generalizable Fundus Image
Segmentation on Unseen Datasets
- Authors: Shujun Wang, Lequan Yu, Kang Li, Xin Yang, Chi-Wing Fu, and Pheng-Ann
Heng
- Abstract summary: We present a novel Domain-oriented Feature Embedding (DoFE) framework to improve the generalization ability of CNNs on unseen target domains.
Our DoFE framework dynamically enriches the image features with additional domain prior knowledge learned from multi-source domains.
Our framework generates satisfying segmentation results on unseen datasets and surpasses other domain generalization and network regularization methods.
- Score: 96.92018649136217
- License: http://arxiv.org/licenses/nonexclusive-distrib/1.0/
- Abstract: Deep convolutional neural networks have significantly boosted the performance
of fundus image segmentation when test datasets have the same distribution as
the training datasets. However, in clinical practice, medical images often
exhibit variations in appearance for various reasons, e.g., different scanner
vendors and image quality. These distribution discrepancies could lead the deep
networks to over-fit on the training datasets and lack generalization ability
on the unseen test datasets. To alleviate this issue, we present a novel
Domain-oriented Feature Embedding (DoFE) framework to improve the
generalization ability of CNNs on unseen target domains by exploring the
knowledge from multiple source domains. Our DoFE framework dynamically enriches
the image features with additional domain prior knowledge learned from
multi-source domains to make the semantic features more discriminative.
Specifically, we introduce a Domain Knowledge Pool to learn and memorize the
prior information extracted from multi-source domains. Then the original image
features are augmented with domain-oriented aggregated features, which are
induced from the knowledge pool based on the similarity between the input image
and multi-source domain images. We further design a novel domain code
prediction branch to infer this similarity and employ an attention-guided
mechanism to dynamically combine the aggregated features with the semantic
features. We comprehensively evaluate our DoFE framework on two fundus image
segmentation tasks, including the optic cup and disc segmentation and vessel
segmentation. Our DoFE framework generates satisfying segmentation results on
unseen datasets and surpasses other domain generalization and network
regularization methods.
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