Machine learning for plant microRNA prediction: A systematic review

• URL: http://arxiv.org/abs/2106.15159v1
• Date: Tue, 29 Jun 2021 08:22:57 GMT
• Title: Machine learning for plant microRNA prediction: A systematic review
• Authors: Shyaman Jayasundara, Sandali Lokuge, Puwasuru Ihalagedara and Damayanthi Herath
• Abstract summary: MicroRNAs (miRNAs) are endogenous small non-coding RNAs that play an important role in gene regulation. computational and machine learning-based approaches have been adopted to predict microRNAs. This systematic review focuses on the machine learning methods developed for identification in plants.
• Score: 0.0
• License: http://arxiv.org/licenses/nonexclusive-distrib/1.0/
• Abstract: MicroRNAs (miRNAs) are endogenous small non-coding RNAs that play an important role in post-transcriptional gene regulation. However, the experimental determination of miRNA sequence and structure is both expensive and time-consuming. Therefore, computational and machine learning-based approaches have been adopted to predict novel microRNAs. With the involvement of data science and machine learning in biology, multiple research studies have been conducted to find microRNAs with different computational methods and different miRNA features. Multiple approaches are discussed in detail considering the learning algorithm/s used, features considered, dataset/s used and the criteria used in evaluations. This systematic review focuses on the machine learning methods developed for miRNA identification in plants. This will help researchers to gain a detailed idea about past studies and identify novel paths that solve drawbacks occurred in past studies. Our findings highlight the need for plant-specific computational methods for miRNA identification.

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