Unsupervised Domain Adaptation for Retinal Vessel Segmentation with
Adversarial Learning and Transfer Normalization
- URL: http://arxiv.org/abs/2108.01821v1
- Date: Wed, 4 Aug 2021 02:45:37 GMT
- Title: Unsupervised Domain Adaptation for Retinal Vessel Segmentation with
Adversarial Learning and Transfer Normalization
- Authors: Wei Feng, Lie Ju, Lin Wang, Kaimin Song, Xin Wang, Xin Zhao, Qingyi
Tao, and Zongyuan Ge
- Abstract summary: We propose an entropy-based adversarial learning strategy to reduce the distribution discrepancy between source and target domains.
A new transfer normalization layer is proposed to further boost the transferability of the deep network.
Our approach yields significant performance gains compared to other state-of-the-art methods.
- Score: 22.186070895966022
- License: http://creativecommons.org/licenses/by/4.0/
- Abstract: Retinal vessel segmentation plays a key role in computer-aided screening,
diagnosis, and treatment of various cardiovascular and ophthalmic diseases.
Recently, deep learning-based retinal vessel segmentation algorithms have
achieved remarkable performance. However, due to the domain shift problem, the
performance of these algorithms often degrades when they are applied to new
data that is different from the training data. Manually labeling new data for
each test domain is often a time-consuming and laborious task. In this work, we
explore unsupervised domain adaptation in retinal vessel segmentation by using
entropy-based adversarial learning and transfer normalization layer to train a
segmentation network, which generalizes well across domains and requires no
annotation of the target domain. Specifically, first, an entropy-based
adversarial learning strategy is developed to reduce the distribution
discrepancy between the source and target domains while also achieving the
objective of entropy minimization on the target domain. In addition, a new
transfer normalization layer is proposed to further boost the transferability
of the deep network. It normalizes the features of each domain separately to
compensate for the domain distribution gap. Besides, it also adaptively selects
those feature channels that are more transferable between domains, thus further
enhancing the generalization performance of the network. We conducted extensive
experiments on three regular fundus image datasets and an ultra-widefield
fundus image dataset, and the results show that our approach yields significant
performance gains compared to other state-of-the-art methods.
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