Diffusion Model based Semi-supervised Learning on Brain Hemorrhage
Images for Efficient Midline Shift Quantification
- URL: http://arxiv.org/abs/2301.00409v1
- Date: Sun, 1 Jan 2023 14:19:52 GMT
- Title: Diffusion Model based Semi-supervised Learning on Brain Hemorrhage
Images for Efficient Midline Shift Quantification
- Authors: Shizhan Gong, Cheng Chen, Yuqi Gong, Nga Yan Chan, Wenao Ma, Calvin
Hoi-Kwan Mak, Jill Abrigo, Qi Dou
- Abstract summary: Brain midline shift (MLS) is one of the most critical factors to be considered for clinical diagnosis and treatment decision-making for intracranial hemorrhage.
We propose a novel semi-supervised framework to accurately measure the scale of MLS from head CT scans.
Our experiment on a real clinical brain hemorrhage dataset has achieved state-of-the-art performance and can generate interpretable deformation fields.
- Score: 14.978566465420572
- License: http://arxiv.org/licenses/nonexclusive-distrib/1.0/
- Abstract: Brain midline shift (MLS) is one of the most critical factors to be
considered for clinical diagnosis and treatment decision-making for
intracranial hemorrhage. Existing computational methods on MLS quantification
not only require intensive labeling in millimeter-level measurement but also
suffer from poor performance due to their dependence on specific landmarks or
simplified anatomical assumptions. In this paper, we propose a novel
semi-supervised framework to accurately measure the scale of MLS from head CT
scans. We formulate the MLS measurement task as a deformation estimation
problem and solve it using a few MLS slices with sparse labels. Meanwhile, with
the help of diffusion models, we are able to use a great number of unlabeled
MLS data and 2793 non-MLS cases for representation learning and regularization.
The extracted representation reflects how the image is different from a non-MLS
image and regularization serves an important role in the sparse-to-dense
refinement of the deformation field. Our experiment on a real clinical brain
hemorrhage dataset has achieved state-of-the-art performance and can generate
interpretable deformation fields.
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