Developing Healthcare Language Model Embedding Spaces
- URL: http://arxiv.org/abs/2403.19802v1
- Date: Thu, 28 Mar 2024 19:31:32 GMT
- Title: Developing Healthcare Language Model Embedding Spaces
- Authors: Niall Taylor, Dan Schofield, Andrey Kormilitzin, Dan W Joyce, Alejo Nevado-Holgado,
- Abstract summary: Pre-trained Large Language Models (LLMs) often struggle on out-of-domain datasets like healthcare focused text.
Three methods are assessed: traditional masked language modeling, Deep Contrastive Learning for Unsupervised Textual Representations (DeCLUTR) and a novel pre-training objective utilizing metadata categories from the healthcare settings.
Contrastively trained models outperform other approaches on the classification tasks, delivering strong performance from limited labeled data and with fewer model parameter updates required.
- Score: 0.20971479389679337
- License: http://creativecommons.org/licenses/by/4.0/
- Abstract: Pre-trained Large Language Models (LLMs) often struggle on out-of-domain datasets like healthcare focused text. We explore specialized pre-training to adapt smaller LLMs to different healthcare datasets. Three methods are assessed: traditional masked language modeling, Deep Contrastive Learning for Unsupervised Textual Representations (DeCLUTR), and a novel pre-training objective utilizing metadata categories from the healthcare settings. These schemes are evaluated on downstream document classification tasks for each dataset, with additional analysis of the resultant embedding spaces. Contrastively trained models outperform other approaches on the classification tasks, delivering strong performance from limited labeled data and with fewer model parameter updates required. While metadata-based pre-training does not further improve classifications across the datasets, it yields interesting embedding cluster separability. All domain adapted LLMs outperform their publicly available general base LLM, validating the importance of domain-specialization. This research illustrates efficient approaches to instill healthcare competency in compact LLMs even under tight computational budgets, an essential capability for responsible and sustainable deployment in local healthcare settings. We provide pre-training guidelines for specialized healthcare LLMs, motivate continued inquiry into contrastive objectives, and demonstrates adaptation techniques to align small LLMs with privacy-sensitive medical tasks.
Related papers
- Using Large Language Models for Expert Prior Elicitation in Predictive Modelling [53.54623137152208]
This study proposes using large language models (LLMs) to elicit expert prior distributions for predictive models.
We compare LLM-elicited and uninformative priors, evaluate whether LLMs truthfully generate parameter distributions, and propose a model selection strategy for in-context learning and prior elicitation.
Our findings show that LLM-elicited prior parameter distributions significantly reduce predictive error compared to uninformative priors in low-data settings.
arXiv Detail & Related papers (2024-11-26T10:13:39Z) - Enhancing In-Hospital Mortality Prediction Using Multi-Representational Learning with LLM-Generated Expert Summaries [3.5508427067904864]
In-hospital mortality (IHM) prediction for ICU patients is critical for timely interventions and efficient resource allocation.
This study integrates structured physiological data and clinical notes with Large Language Model (LLM)-generated expert summaries to improve IHM prediction accuracy.
arXiv Detail & Related papers (2024-11-25T16:36:38Z) - When Raw Data Prevails: Are Large Language Model Embeddings Effective in Numerical Data Representation for Medical Machine Learning Applications? [8.89829757177796]
We examine the effectiveness of vector representations from last hidden states of Large Language Models for medical diagnostics and prognostics.
We focus on instruction-tuned LLMs in a zero-shot setting to represent abnormal physiological data and evaluate their utilities as feature extractors.
Although findings suggest the raw data features still prevails in medical ML tasks, zero-shot LLM embeddings demonstrate competitive results.
arXiv Detail & Related papers (2024-08-15T03:56:40Z) - SELF-GUIDE: Better Task-Specific Instruction Following via Self-Synthetic Finetuning [70.21358720599821]
Large language models (LLMs) hold the promise of solving diverse tasks when provided with appropriate natural language prompts.
We propose SELF-GUIDE, a multi-stage mechanism in which we synthesize task-specific input-output pairs from the student LLM.
We report an absolute improvement of approximately 15% for classification tasks and 18% for generation tasks in the benchmark's metrics.
arXiv Detail & Related papers (2024-07-16T04:41:58Z) - Self-training Large Language Models through Knowledge Detection [26.831873737733737]
Large language models (LLMs) often necessitate extensive labeled datasets and training compute to achieve impressive performance across downstream tasks.
This paper explores a self-training paradigm, where the LLM autonomously curates its own labels and selectively trains on unknown data samples.
Empirical evaluations demonstrate significant improvements in reducing hallucination in generation across multiple subjects.
arXiv Detail & Related papers (2024-06-17T07:25:09Z) - Knowledge-grounded Adaptation Strategy for Vision-language Models: Building Unique Case-set for Screening Mammograms for Residents Training [5.819704618007536]
A visual-language model (VLM) pre-trained on natural images and text pairs poses a significant barrier when applied to medical contexts.
We propose a framework designed to adeptly tailor VLMs to the medical domain, employing selective sampling and hard-negative mining techniques.
arXiv Detail & Related papers (2024-05-30T04:04:36Z) - Evaluating Large Language Models for Health-Related Text Classification Tasks with Public Social Media Data [3.9459077974367833]
Large language models (LLMs) have demonstrated remarkable success in NLP tasks.
We benchmarked one supervised classic machine learning model based on Support Vector Machines (SVMs), three supervised pretrained language models (PLMs) based on RoBERTa, BERTweet, and SocBERT, and two LLM based classifiers (GPT3.5 and GPT4), across 6 text classification tasks.
Our comprehensive experiments demonstrate that employ-ing data augmentation using LLMs (GPT-4) with relatively small human-annotated data to train lightweight supervised classification models achieves superior results compared to training with human-annotated data
arXiv Detail & Related papers (2024-03-27T22:05:10Z) - Learnable Weight Initialization for Volumetric Medical Image Segmentation [66.3030435676252]
We propose a learnable weight-based hybrid medical image segmentation approach.
Our approach is easy to integrate into any hybrid model and requires no external training data.
Experiments on multi-organ and lung cancer segmentation tasks demonstrate the effectiveness of our approach.
arXiv Detail & Related papers (2023-06-15T17:55:05Z) - Interpretable Medical Diagnostics with Structured Data Extraction by
Large Language Models [59.89454513692417]
Tabular data is often hidden in text, particularly in medical diagnostic reports.
We propose a novel, simple, and effective methodology for extracting structured tabular data from textual medical reports, called TEMED-LLM.
We demonstrate that our approach significantly outperforms state-of-the-art text classification models in medical diagnostics.
arXiv Detail & Related papers (2023-06-08T09:12:28Z) - An Iterative Optimizing Framework for Radiology Report Summarization with ChatGPT [80.33783969507458]
The 'Impression' section of a radiology report is a critical basis for communication between radiologists and other physicians.
Recent studies have achieved promising results in automatic impression generation using large-scale medical text data.
These models often require substantial amounts of medical text data and have poor generalization performance.
arXiv Detail & Related papers (2023-04-17T17:13:42Z) - Vision-Language Modelling For Radiological Imaging and Reports In The
Low Data Regime [70.04389979779195]
This paper explores training medical vision-language models (VLMs) where the visual and language inputs are embedded into a common space.
We explore several candidate methods to improve low-data performance, including adapting generic pre-trained models to novel image and text domains.
Using text-to-image retrieval as a benchmark, we evaluate the performance of these methods with variable sized training datasets of paired chest X-rays and radiological reports.
arXiv Detail & Related papers (2023-03-30T18:20:00Z)
This list is automatically generated from the titles and abstracts of the papers in this site.
This site does not guarantee the quality of this site (including all information) and is not responsible for any consequences.