Opportunities in deep learning methods development for computational biology
- URL: http://arxiv.org/abs/2406.08686v1
- Date: Wed, 12 Jun 2024 22:58:45 GMT
- Title: Opportunities in deep learning methods development for computational biology
- Authors: Alex Jihun Lee, Reza Abbasi-Asl,
- Abstract summary: Molecular technologies underlie an enormous growth in the size of data sets pertaining to biology and biomedicine.
These advances parallel those in the deep learning subfield of machine learning.
Many of these tools have not fully proliferated into the computational biology and bioinformatics fields.
- Score: 0.0
- License: http://creativecommons.org/licenses/by/4.0/
- Abstract: Advances in molecular technologies underlie an enormous growth in the size of data sets pertaining to biology and biomedicine. These advances parallel those in the deep learning subfield of machine learning. Components in the differentiable programming toolbox that makes deep learning possible are allowing computer scientists to address an increasingly large array of problems with flexible and effective tools. However many of these tools have not fully proliferated into the computational biology and bioinformatics fields. In this perspective we survey some of these advances and highlight exemplary examples of their utilization in the biosciences, with the goal of increasing awareness among practitioners of emerging opportunities to blend expert knowledge with newly emerging deep learning architectural tools.
Related papers
- Empowering Biomedical Discovery with AI Agents [15.125735219811268]
We envision "AI scientists" as systems capable of skeptical learning and reasoning.
Biomedical AI agents combine human creativity and expertise with AI's ability to analyze large datasets.
AI agents can impact areas ranging from virtual cell simulation, programmable control of phenotypes, and the design of cellular circuits to developing new therapies.
arXiv Detail & Related papers (2024-04-03T16:08:01Z) - EndToEndML: An Open-Source End-to-End Pipeline for Machine Learning Applications [0.2826977330147589]
We propose a web-based end-to-end pipeline that is capable of preprocessing, training, evaluating, and visualizing machine learning models.
Our library assists in recognizing, classifying, clustering, and predicting a wide range of multi-modal, multi-sensor datasets.
arXiv Detail & Related papers (2024-03-27T02:24:38Z) - An Evaluation of Large Language Models in Bioinformatics Research [52.100233156012756]
We study the performance of large language models (LLMs) on a wide spectrum of crucial bioinformatics tasks.
These tasks include the identification of potential coding regions, extraction of named entities for genes and proteins, detection of antimicrobial and anti-cancer peptides, molecular optimization, and resolution of educational bioinformatics problems.
Our findings indicate that, given appropriate prompts, LLMs like GPT variants can successfully handle most of these tasks.
arXiv Detail & Related papers (2024-02-21T11:27:31Z) - Diversifying Knowledge Enhancement of Biomedical Language Models using
Adapter Modules and Knowledge Graphs [54.223394825528665]
We develop an approach that uses lightweight adapter modules to inject structured biomedical knowledge into pre-trained language models.
We use two large KGs, the biomedical knowledge system UMLS and the novel biochemical OntoChem, with two prominent biomedical PLMs, PubMedBERT and BioLinkBERT.
We show that our methodology leads to performance improvements in several instances while keeping requirements in computing power low.
arXiv Detail & Related papers (2023-12-21T14:26:57Z) - ProBio: A Protocol-guided Multimodal Dataset for Molecular Biology Lab [67.24684071577211]
The challenge of replicating research results has posed a significant impediment to the field of molecular biology.
We first curate a comprehensive multimodal dataset, named ProBio, as an initial step towards this objective.
Next, we devise two challenging benchmarks, transparent solution tracking and multimodal action recognition, to emphasize the unique characteristics and difficulties associated with activity understanding in BioLab settings.
arXiv Detail & Related papers (2023-11-01T14:44:01Z) - Brain-Inspired Computational Intelligence via Predictive Coding [89.6335791546526]
Predictive coding (PC) has shown promising performance in machine intelligence tasks.
PC can model information processing in different brain areas, can be used in cognitive control and robotics.
arXiv Detail & Related papers (2023-08-15T16:37:16Z) - Machine Learning for Uncovering Biological Insights in Spatial
Transcriptomics Data [0.0]
Development and homeostasis in multicellular systems require exquisite control over spatial molecular pattern formation and maintenance.
Advances in spatial transcriptomics (ST) have led to rapid development of innovative machine learning (ML) tools.
We summarize major ST analysis goals that ML can help address and current analysis trends.
arXiv Detail & Related papers (2023-03-29T14:22:08Z) - A Review of Deep Learning Techniques for Protein Function Prediction [0.0]
This review paper analyzes the recent developments in approaches for the task of predicting protein function using deep learning.
We highlight the emergence of the modern State of The Art (SOTA) deep learning models which have achieved groundbreaking results in the field of computer vision, natural language processing and multi-modal learning.
arXiv Detail & Related papers (2022-10-27T20:30:25Z) - Machine learning in bioprocess development: From promise to practice [58.720142291102135]
Data-driven methods like machine learning (ML) approaches have a high potential to rationally explore large design spaces.
The aim of this review is to demonstrate how ML methods have been applied so far in bioprocess development.
arXiv Detail & Related papers (2022-10-04T13:48:59Z) - Ten Quick Tips for Deep Learning in Biology [116.78436313026478]
Machine learning is concerned with the development and applications of algorithms that can recognize patterns in data and use them for predictive modeling.
Deep learning has become its own subfield of machine learning.
In the context of biological research, deep learning has been increasingly used to derive novel insights from high-dimensional biological data.
arXiv Detail & Related papers (2021-05-29T21:02:44Z)
This list is automatically generated from the titles and abstracts of the papers in this site.
This site does not guarantee the quality of this site (including all information) and is not responsible for any consequences.