Deep Learning for Disease Outbreak Prediction: A Robust Early Warning Signal for Transcritical Bifurcations
- URL: http://arxiv.org/abs/2501.07764v1
- Date: Tue, 14 Jan 2025 00:47:05 GMT
- Title: Deep Learning for Disease Outbreak Prediction: A Robust Early Warning Signal for Transcritical Bifurcations
- Authors: Reza Miry, Amit K. Chakraborty, Russell Greiner, Mark A. Lewis, Hao Wang, Tianyu Guan, Pouria Ramazi,
- Abstract summary: Early Warning Signals (EWSs) are vital for implementing preventive measures before a disease turns into a pandemic.
measurements during disease outbreaks are often corrupted by different noise sources.
This study bridges advancements in deep learning with the ability to provide robust early warning signals in noisy environments.
- Score: 6.616648875013729
- License:
- Abstract: Early Warning Signals (EWSs) are vital for implementing preventive measures before a disease turns into a pandemic. While new diseases exhibit unique behaviors, they often share fundamental characteristics from a dynamical systems perspective. Moreover, measurements during disease outbreaks are often corrupted by different noise sources, posing challenges for Time Series Classification (TSC) tasks. In this study, we address the problem of having a robust EWS for disease outbreak prediction using a best-performing deep learning model in the domain of TSC. We employed two simulated datasets to train the model: one representing generated dynamical systems with randomly selected polynomial terms to model new disease behaviors, and another simulating noise-induced disease dynamics to account for noisy measurements. The model's performance was analyzed using both simulated data from different disease models and real-world data, including influenza and COVID-19. Results demonstrate that the proposed model outperforms previous models, effectively providing EWSs of impending outbreaks across various scenarios. This study bridges advancements in deep learning with the ability to provide robust early warning signals in noisy environments, making it highly applicable to real-world crises involving emerging disease outbreaks.
Related papers
- An early warning indicator trained on stochastic disease-spreading models with different noises [8.228025953197855]
Early warning signals (EWSs) are indispensable for effective public health mitigation strategies.
The dynamics of real-world disease spread, influenced by diverse sources of noise, pose a significant challenge in developing reliable EWSs.
This study contributes to advancing early warning capabilities by addressing the intricate dynamics inherent in real-world disease spread.
arXiv Detail & Related papers (2024-03-24T16:49:55Z) - PEMS: Pre-trained Epidemic Time-series Models [23.897701882327972]
We introduce Pre-trained Epidemic Time-Series Models (PEMS)
PEMS learn from diverse time-series datasets of a variety of diseases by formulating pre-training as a set of self-supervised learning (SSL) tasks.
The resultant PEM outperforms previous state-of-the-art methods in various downstream time-series tasks across datasets of varying seasonal patterns, geography, and mechanism of contagion including the novel Covid-19 pandemic unseen in pre-trained data with better efficiency using smaller fraction of datasets.
arXiv Detail & Related papers (2023-11-14T01:40:21Z) - MedDiffusion: Boosting Health Risk Prediction via Diffusion-based Data
Augmentation [58.93221876843639]
This paper introduces a novel, end-to-end diffusion-based risk prediction model, named MedDiffusion.
It enhances risk prediction performance by creating synthetic patient data during training to enlarge sample space.
It discerns hidden relationships between patient visits using a step-wise attention mechanism, enabling the model to automatically retain the most vital information for generating high-quality data.
arXiv Detail & Related papers (2023-10-04T01:36:30Z) - SPADE4: Sparsity and Delay Embedding based Forecasting of Epidemics [2.578242050187029]
We propose Sparsity and Delay Embedding based Forecasting (SPADE4) for predicting epidemics.
We show that our approach outperforms compartmental models when applied to both simulated and real data.
arXiv Detail & Related papers (2022-11-11T23:39:48Z) - Data-Centric Epidemic Forecasting: A Survey [56.99209141838794]
This survey delves into various data-driven methodological and practical advancements.
We enumerate the large number of epidemiological datasets and novel data streams that are relevant to epidemic forecasting.
We also discuss experiences and challenges that arise in real-world deployment of these forecasting systems.
arXiv Detail & Related papers (2022-07-19T16:15:11Z) - Epicasting: An Ensemble Wavelet Neural Network (EWNet) for Forecasting
Epidemics [2.705025060422369]
Infectious diseases remain among the top contributors to human illness and death worldwide.
Forecasts of epidemics can assist stakeholders in tailoring countermeasures to the situation at hand.
arXiv Detail & Related papers (2022-06-21T19:31:25Z) - Adversarial Sample Enhanced Domain Adaptation: A Case Study on
Predictive Modeling with Electronic Health Records [57.75125067744978]
We propose a data augmentation method to facilitate domain adaptation.
adversarially generated samples are used during domain adaptation.
Results confirm the effectiveness of our method and the generality on different tasks.
arXiv Detail & Related papers (2021-01-13T03:20:20Z) - STELAR: Spatio-temporal Tensor Factorization with Latent Epidemiological
Regularization [76.57716281104938]
We develop a tensor method to predict the evolution of epidemic trends for many regions simultaneously.
STELAR enables long-term prediction by incorporating latent temporal regularization through a system of discrete-time difference equations.
We conduct experiments using both county- and state-level COVID-19 data and show that our model can identify interesting latent patterns of the epidemic.
arXiv Detail & Related papers (2020-12-08T21:21:47Z) - An Optimal Control Approach to Learning in SIDARTHE Epidemic model [67.22168759751541]
We propose a general approach for learning time-variant parameters of dynamic compartmental models from epidemic data.
We forecast the epidemic evolution in Italy and France.
arXiv Detail & Related papers (2020-10-28T10:58:59Z) - OutbreakFlow: Model-based Bayesian inference of disease outbreak
dynamics with invertible neural networks and its application to the COVID-19
pandemics in Germany [0.19791587637442667]
We present a novel combination of epidemiological modeling with specialized neural networks.
We are able to obtain reliable probabilistic estimates for important disease characteristics, such as generation time, fraction of undetected infections, likelihood of transmission before symptom onset, and reporting delays using a very moderate amount of real-world observations.
arXiv Detail & Related papers (2020-10-01T11:01:49Z) - A General Framework for Survival Analysis and Multi-State Modelling [70.31153478610229]
We use neural ordinary differential equations as a flexible and general method for estimating multi-state survival models.
We show that our model exhibits state-of-the-art performance on popular survival data sets and demonstrate its efficacy in a multi-state setting.
arXiv Detail & Related papers (2020-06-08T19:24:54Z)
This list is automatically generated from the titles and abstracts of the papers in this site.
This site does not guarantee the quality of this site (including all information) and is not responsible for any consequences.