DiffRenderGAN: Addressing Training Data Scarcity in Deep Segmentation Networks for Quantitative Nanomaterial Analysis through Differentiable Rendering and Generative Modelling
- URL: http://arxiv.org/abs/2502.09477v1
- Date: Thu, 13 Feb 2025 16:41:44 GMT
- Title: DiffRenderGAN: Addressing Training Data Scarcity in Deep Segmentation Networks for Quantitative Nanomaterial Analysis through Differentiable Rendering and Generative Modelling
- Authors: Dennis Possart, Leonid Mill, Florian Vollnhals, Tor Hildebrand, Peter Suter, Mathis Hoffmann, Jonas Utz, Daniel Augsburger, Mareike Thies, Mingxuan Wu, Fabian Wagner, George Sarau, Silke Christiansen, Katharina Breininger,
- Abstract summary: Deep learning segmentation networks enable automated insights and replace subjective methods with precise quantitative analysis.
We introduce DiffRenderGAN, a novel generative model designed to produce annotated synthetic data.
This approach reduces the need for manual intervention and enhances segmentation performance compared to existing synthetic data methods.
- Score: 0.1135917885955104
- License:
- Abstract: Nanomaterials exhibit distinctive properties governed by parameters such as size, shape, and surface characteristics, which critically influence their applications and interactions across technological, biological, and environmental contexts. Accurate quantification and understanding of these materials are essential for advancing research and innovation. In this regard, deep learning segmentation networks have emerged as powerful tools that enable automated insights and replace subjective methods with precise quantitative analysis. However, their efficacy depends on representative annotated datasets, which are challenging to obtain due to the costly imaging of nanoparticles and the labor-intensive nature of manual annotations. To overcome these limitations, we introduce DiffRenderGAN, a novel generative model designed to produce annotated synthetic data. By integrating a differentiable renderer into a Generative Adversarial Network (GAN) framework, DiffRenderGAN optimizes textural rendering parameters to generate realistic, annotated nanoparticle images from non-annotated real microscopy images. This approach reduces the need for manual intervention and enhances segmentation performance compared to existing synthetic data methods by generating diverse and realistic data. Tested on multiple ion and electron microscopy cases, including titanium dioxide (TiO$_2$), silicon dioxide (SiO$_2$)), and silver nanowires (AgNW), DiffRenderGAN bridges the gap between synthetic and real data, advancing the quantification and understanding of complex nanomaterial systems.
Related papers
- Unlocking Potential Binders: Multimodal Pretraining DEL-Fusion for Denoising DNA-Encoded Libraries [51.72836644350993]
Multimodal Pretraining DEL-Fusion model (MPDF)
We develop pretraining tasks applying contrastive objectives between different compound representations and their text descriptions.
We propose a novel DEL-fusion framework that amalgamates compound information at the atomic, submolecular, and molecular levels.
arXiv Detail & Related papers (2024-09-07T17:32:21Z) - Synthetic Image Learning: Preserving Performance and Preventing Membership Inference Attacks [5.0243930429558885]
This paper introduces Knowledge Recycling (KR), a pipeline designed to optimise the generation and use of synthetic data for training downstream classifiers.
At the heart of this pipeline is Generative Knowledge Distillation (GKD), the proposed technique that significantly improves the quality and usefulness of the information.
The results show a significant reduction in the performance gap between models trained on real and synthetic data, with models based on synthetic data outperforming those trained on real data in some cases.
arXiv Detail & Related papers (2024-07-22T10:31:07Z) - Benchmark on Drug Target Interaction Modeling from a Structure Perspective [48.60648369785105]
Drug-target interaction prediction is crucial to drug discovery and design.
Recent methods, such as those based on graph neural networks (GNNs) and Transformers, demonstrate exceptional performance across various datasets.
We conduct a comprehensive survey and benchmark for drug-target interaction modeling from a structure perspective, via integrating tens of explicit (i.e., GNN-based) and implicit (i.e., Transformer-based) structure learning algorithms.
arXiv Detail & Related papers (2024-07-04T16:56:59Z) - Generalization Across Experimental Parameters in Machine Learning
Analysis of High Resolution Transmission Electron Microscopy Datasets [0.0]
We train and validate neural networks across curated, experimentally-collected high-resolution TEM image datasets of nanoparticles.
We find that our neural networks are not robust across microscope parameters, but do generalize across certain sample parameters.
arXiv Detail & Related papers (2023-06-20T19:13:49Z) - ContraNeRF: Generalizable Neural Radiance Fields for Synthetic-to-real
Novel View Synthesis via Contrastive Learning [102.46382882098847]
We first investigate the effects of synthetic data in synthetic-to-real novel view synthesis.
We propose to introduce geometry-aware contrastive learning to learn multi-view consistent features with geometric constraints.
Our method can render images with higher quality and better fine-grained details, outperforming existing generalizable novel view synthesis methods in terms of PSNR, SSIM, and LPIPS.
arXiv Detail & Related papers (2023-03-20T12:06:14Z) - Combining Variational Autoencoders and Physical Bias for Improved
Microscopy Data Analysis [0.0]
We present a physics augmented machine learning method which disentangles factors of variability within the data.
Our method is applied to various materials, including NiO-LSMO, BiFeO3, and graphene.
The results demonstrate the effectiveness of our approach in extracting meaningful information from large volumes of imaging data.
arXiv Detail & Related papers (2023-02-08T17:35:38Z) - Automated Classification of Nanoparticles with Various Ultrastructures
and Sizes [0.6927055673104933]
We present a deep-learning based method for nanoparticles measurement and classification trained from a small data set of scanning transmission electron microscopy images.
Our approach is comprised of two stages: localization, i.e., detection of nanoparticles, and classification, i.e., categorization of their ultrastructure.
We show how the generation of synthetic images, either using image processing or using various image generation neural networks, can be used to improve the results in both stages.
arXiv Detail & Related papers (2022-07-28T11:31:43Z) - Neural Implicit Representations for Physical Parameter Inference from a Single Video [49.766574469284485]
We propose to combine neural implicit representations for appearance modeling with neural ordinary differential equations (ODEs) for modelling physical phenomena.
Our proposed model combines several unique advantages: (i) Contrary to existing approaches that require large training datasets, we are able to identify physical parameters from only a single video.
The use of neural implicit representations enables the processing of high-resolution videos and the synthesis of photo-realistic images.
arXiv Detail & Related papers (2022-04-29T11:55:35Z) - Synthetic Image Rendering Solves Annotation Problem in Deep Learning
Nanoparticle Segmentation [5.927116192179681]
We show that using a rendering software allows to generate realistic, synthetic training data to train a state-of-the art deep neural network.
We derive a segmentation accuracy that is comparable to man-made annotations for toxicologically relevant metal-oxide nanoparticles ensembles.
arXiv Detail & Related papers (2020-11-20T17:05:36Z) - Towards an Automatic Analysis of CHO-K1 Suspension Growth in
Microfluidic Single-cell Cultivation [63.94623495501023]
We propose a novel Machine Learning architecture, which allows us to infuse a neural deep network with human-powered abstraction on the level of data.
Specifically, we train a generative model simultaneously on natural and synthetic data, so that it learns a shared representation, from which a target variable, such as the cell count, can be reliably estimated.
arXiv Detail & Related papers (2020-10-20T08:36:51Z) - Multi-View Graph Neural Networks for Molecular Property Prediction [67.54644592806876]
We present Multi-View Graph Neural Network (MV-GNN), a multi-view message passing architecture.
In MV-GNN, we introduce a shared self-attentive readout component and disagreement loss to stabilize the training process.
We further boost the expressive power of MV-GNN by proposing a cross-dependent message passing scheme.
arXiv Detail & Related papers (2020-05-17T04:46:07Z)
This list is automatically generated from the titles and abstracts of the papers in this site.
This site does not guarantee the quality of this site (including all information) and is not responsible for any consequences.