Unified Medical Image Segmentation with State Space Modeling Snake

• URL: http://arxiv.org/abs/2507.12760v1
• Date: Thu, 17 Jul 2025 03:32:32 GMT
• Title: Unified Medical Image Segmentation with State Space Modeling Snake
• Authors: Ruicheng Zhang, Haowei Guo, Kanghui Tian, Jun Zhou, Mingliang Yan, Zeyu Zhang, Shen Zhao,
• Abstract summary: We propose Mamba Snake, a novel space deep snake framework enhanced by state-of-the-art modeling for Unified Medical Image System (UMIS)<n>Mamba Snake frames multi-con evolution as a hierarchical state space atlas, effectively macroscopic inter-organ topological relationships and microscopic contour refinements.<n>Mamba Snake's superior performance, with an average improvement of 3% over state-of-the-art methods.
• Score: 7.855562142338835
• License: http://arxiv.org/licenses/nonexclusive-distrib/1.0/
• Abstract: Unified Medical Image Segmentation (UMIS) is critical for comprehensive anatomical assessment but faces challenges due to multi-scale structural heterogeneity. Conventional pixel-based approaches, lacking object-level anatomical insight and inter-organ relational modeling, struggle with morphological complexity and feature conflicts, limiting their efficacy in UMIS. We propose Mamba Snake, a novel deep snake framework enhanced by state space modeling for UMIS. Mamba Snake frames multi-contour evolution as a hierarchical state space atlas, effectively modeling macroscopic inter-organ topological relationships and microscopic contour refinements. We introduce a snake-specific vision state space module, the Mamba Evolution Block (MEB), which leverages effective spatiotemporal information aggregation for adaptive refinement of complex morphologies. Energy map shape priors further ensure robust long-range contour evolution in heterogeneous data. Additionally, a dual-classification synergy mechanism is incorporated to concurrently optimize detection and segmentation, mitigating under-segmentation of microstructures in UMIS. Extensive evaluations across five clinical datasets reveal Mamba Snake's superior performance, with an average Dice improvement of 3\% over state-of-the-art methods.

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