SurvKAN: A Fully Parametric Survival Model Based on Kolmogorov-Arnold Networks
- URL: http://arxiv.org/abs/2602.02179v1
- Date: Mon, 02 Feb 2026 14:49:14 GMT
- Title: SurvKAN: A Fully Parametric Survival Model Based on Kolmogorov-Arnold Networks
- Authors: Marina Mastroleo, Alberto Archetti, Federico Mastroleo, Matteo Matteucci,
- Abstract summary: We introduce SurvKAN, a fully parametric, time-continuous survival model based on Kolmogorov-Arnold Networks (KANs)<n>SurvKAN treats time as an explicit input to a KAN that directly predicts the log-hazard function, enabling end-to-end training on the full survival likelihood.
- Score: 7.352227733654751
- License: http://creativecommons.org/licenses/by/4.0/
- Abstract: Accurate prediction of time-to-event outcomes is critical for clinical decision-making, treatment planning, and resource allocation in modern healthcare. While classical survival models such as Cox remain widely adopted in standard practice, they rely on restrictive assumptions, including linear covariate relationships and proportional hazards over time, that often fail to capture real-world clinical dynamics. Recent deep learning approaches like DeepSurv and DeepHit offer improved expressivity but sacrifice interpretability, limiting clinical adoption where trust and transparency are paramount. Hybrid models incorporating Kolmogorov-Arnold Networks (KANs), such as CoxKAN, have begun to address this trade-off but remain constrained by the semi-parametric Cox framework. In this work we introduce SurvKAN, a fully parametric, time-continuous survival model based on KAN architectures that eliminates the proportional hazards constraint. SurvKAN treats time as an explicit input to a KAN that directly predicts the log-hazard function, enabling end-to-end training on the full survival likelihood. Our architecture preserves interpretability through learnable univariate functions that indicate how individual features influence risk over time. Extensive experiments on standard survival benchmarks demonstrate that SurvKAN achieves competitive or superior performance compared to classical and state-of-the-art baselines across concordance and calibration metrics. Additionally, interpretability analyses reveal clinically meaningful patterns that align with medical domain knowledge.
Related papers
- Suppressing Prior-Comparison Hallucinations in Radiology Report Generation via Semantically Decoupled Latent Steering [94.37535002230504]
We develop a training-free, inference-time control framework termed Semantically Decoupled Latent Steering.<n>Our approach constructs a semantic-free intervention vector via large language model (LLM)-driven semantic decomposition.<n>We show that our approach significantly reduces the probability of historical hallucinations.
arXiv Detail & Related papers (2026-02-27T04:49:01Z) - Deep Variational Contrastive Learning for Joint Risk Stratification and Time-to-Event Estimation [9.592144785458443]
CONVERSE is a deep survival model that unifies variational autoencoders with contrastive learning for interpretable risk stratification.<n>It achieves competitive or superior performance compared to existing deep survival methods, while maintaining meaningful patient stratification.
arXiv Detail & Related papers (2026-02-01T18:07:40Z) - Adaptable Cardiovascular Disease Risk Prediction from Heterogeneous Data using Large Language Models [70.64969663547703]
AdaCVD is an adaptable CVD risk prediction framework built on large language models extensively fine-tuned on over half a million participants from the UK Biobank.<n>It addresses key clinical challenges across three dimensions: it flexibly incorporates comprehensive yet variable patient information; it seamlessly integrates both structured data and unstructured text; and it rapidly adapts to new patient populations using minimal additional data.
arXiv Detail & Related papers (2025-05-30T14:42:02Z) - Efficient Epistemic Uncertainty Estimation in Cerebrovascular Segmentation [1.3980986259786223]
We introduce an efficient ensemble model combining the advantages of Bayesian Approximation and Deep Ensembles.<n>Areas of high model uncertainty and erroneous predictions are aligned which demonstrates the effectiveness and reliability of the approach.
arXiv Detail & Related papers (2025-03-28T09:39:37Z) - CoxKAN: Kolmogorov-Arnold Networks for Interpretable, High-Performance Survival Analysis [0.3213991044370425]
Kolmogorov-Arnold Networks (KANs) were recently proposed as an interpretable and accurate alternative to multi-layer perceptrons (MLPs)
We introduce CoxKAN, a Cox proportional hazards Kolmogorov-Arnold Network for interpretable, high-performance survival analysis.
arXiv Detail & Related papers (2024-09-06T13:59:58Z) - Deep State-Space Generative Model For Correlated Time-to-Event Predictions [54.3637600983898]
We propose a deep latent state-space generative model to capture the interactions among different types of correlated clinical events.
Our method also uncovers meaningful insights about the latent correlations among mortality and different types of organ failures.
arXiv Detail & Related papers (2024-07-28T02:42:36Z) - TREEMENT: Interpretable Patient-Trial Matching via Personalized Dynamic
Tree-Based Memory Network [54.332862955411656]
Clinical trials are critical for drug development but often suffer from expensive and inefficient patient recruitment.
In recent years, machine learning models have been proposed for speeding up patient recruitment via automatically matching patients with clinical trials.
We introduce a dynamic tree-based memory network model named TREEMENT to provide accurate and interpretable patient trial matching.
arXiv Detail & Related papers (2023-07-19T12:35:09Z) - FastCPH: Efficient Survival Analysis for Neural Networks [57.03275837523063]
We propose FastCPH, a new method that runs in linear time and supports both the standard Breslow and Efron methods for tied events.
We also demonstrate the performance of FastCPH combined with LassoNet, a neural network that provides interpretability through feature sparsity.
arXiv Detail & Related papers (2022-08-21T03:35:29Z) - SurvLatent ODE : A Neural ODE based time-to-event model with competing
risks for longitudinal data improves cancer-associated Deep Vein Thrombosis
(DVT) prediction [68.8204255655161]
We propose a generative time-to-event model, SurvLatent ODE, which parameterizes a latent representation under irregularly sampled data.
Our model then utilizes the latent representation to flexibly estimate survival times for multiple competing events without specifying shapes of event-specific hazard function.
SurvLatent ODE outperforms the current clinical standard Khorana Risk scores for stratifying DVT risk groups.
arXiv Detail & Related papers (2022-04-20T17:28:08Z) - WRSE -- a non-parametric weighted-resolution ensemble for predicting
individual survival distributions in the ICU [0.251657752676152]
Dynamic assessment of mortality risk in the intensive care unit (ICU) can be used to stratify patients, inform about treatment effectiveness or serve as part of an early-warning system.
We show competitive results with state-of-the-art probabilistic models, while greatly reducing training time by factors of 2-9x.
arXiv Detail & Related papers (2020-11-02T10:13:59Z) - DeepHazard: neural network for time-varying risks [0.6091702876917281]
We propose a new flexible method for survival prediction: DeepHazard, a neural network for time-varying risks.
Our approach is tailored for a wide range of continuous hazards forms, with the only restriction of being additive in time.
Numerical examples illustrate that our approach outperforms existing state-of-the-art methodology in terms of predictive capability evaluated through the C-index metric.
arXiv Detail & Related papers (2020-07-26T21:01:49Z) - Neural Topic Models with Survival Supervision: Jointly Predicting Time-to-Event Outcomes and Learning How Clinical Features Relate [10.709447977149532]
We present a neural network framework for learning a survival model to predict a time-to-event outcome.
In particular, we model each subject as a distribution over "topics"
The presence of a topic in a subject means that specific clinical features are more likely to appear for the subject.
arXiv Detail & Related papers (2020-07-15T16:20:04Z) - A General Framework for Survival Analysis and Multi-State Modelling [70.31153478610229]
We use neural ordinary differential equations as a flexible and general method for estimating multi-state survival models.
We show that our model exhibits state-of-the-art performance on popular survival data sets and demonstrate its efficacy in a multi-state setting.
arXiv Detail & Related papers (2020-06-08T19:24:54Z)
This list is automatically generated from the titles and abstracts of the papers in this site.
This site does not guarantee the quality of this site (including all information) and is not responsible for any consequences.