AI Agents Can Already Autonomously Perform Experimental High Energy Physics

• URL: http://arxiv.org/abs/2603.20179v1
• Date: Fri, 20 Mar 2026 17:55:27 GMT
• Title: AI Agents Can Already Autonomously Perform Experimental High Energy Physics
• Abstract summary: Large language model-based AI agents are now able to autonomously execute portions of a high energy physics analysis pipeline with minimal expert-curated input.<n>We present a proof-of-concept framework that integrates autonomous analysis agents with literature-based knowledge retrieval and multi-agent review.
• Score: 0.0431528684314271
• License: http://creativecommons.org/licenses/by/4.0/
• Abstract: Large language model-based AI agents are now able to autonomously execute substantial portions of a high energy physics (HEP) analysis pipeline with minimal expert-curated input. Given access to a HEP dataset, an execution framework, and a corpus of prior experimental literature, we find that Claude Code succeeds in automating all stages of a typical analysis: event selection, background estimation, uncertainty quantification, statistical inference, and paper drafting. We argue that the experimental HEP community is underestimating the current capabilities of these systems, and that most proposed agentic workflows are too narrowly scoped or scaffolded to specific analysis structures. We present a proof-of-concept framework, Just Furnish Context (JFC), that integrates autonomous analysis agents with literature-based knowledge retrieval and multi-agent review, and show that this is sufficient to plan, execute, and document a credible high energy physics analysis. We demonstrate this by conducting analyses on open data from ALEPH, DELPHI, and CMS to perform electroweak, QCD, and Higgs boson measurements. Rather than replacing physicists, these tools promise to offload the repetitive technical burden of analysis code development, freeing researchers to focus on physics insight, truly novel method development, and rigorous validation. Given these developments, we advocate for new strategies for how the community trains students, organizes analysis efforts, and allocates human expertise.

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