An Explainable Vision-Language Model Framework with Adaptive PID-Tversky Loss for Lumbar Spinal Stenosis Diagnosis
- URL: http://arxiv.org/abs/2604.02502v1
- Date: Thu, 02 Apr 2026 20:18:35 GMT
- Title: An Explainable Vision-Language Model Framework with Adaptive PID-Tversky Loss for Lumbar Spinal Stenosis Diagnosis
- Abstract summary: Existing vision-language models fail to address the extreme class imbalance prevalent in clinical segmentation datasets.<n>We present an end-to-end Explainable Vision-Language Model framework designed to overcome these limitations.<n>We show considerable performance: a diagnostic classification accuracy of 90.69%, a macro-averaged Dice score of 0.9512 for segmentation, and a CIDEr score of 92.80%.
- Score: 1.2871968485402088
- License: http://creativecommons.org/licenses/by/4.0/
- Abstract: Lumbar Spinal Stenosis (LSS) diagnosis remains a critical clinical challenge, with diagnosis heavily dependent on labor-intensive manual interpretation of multi-view Magnetic Resonance Imaging (MRI), leading to substantial inter-observer variability and diagnostic delays. Existing vision-language models simultaneously fail to address the extreme class imbalance prevalent in clinical segmentation datasets while preserving spatial accuracy, primarily due to global pooling mechanisms that discard crucial anatomical hierarchies. We present an end-to-end Explainable Vision-Language Model framework designed to overcome these limitations, achieved through two principal objectives. We propose a Spatial Patch Cross-Attention module that enables precise, text-directed localization of spinal anomalies with spatial precision. A novel Adaptive PID-Tversky Loss function by integrating control theory principles dynamically further modifies training penalties to specifically address difficult, under-segmented minority instances. By incorporating foundational VLMs alongside an Automated Radiology Report Generation module, our framework demonstrates considerable performance: a diagnostic classification accuracy of 90.69%, a macro-averaged Dice score of 0.9512 for segmentation, and a CIDEr score of 92.80%. Furthermore, the framework shows explainability by converting complex segmentation predictions into radiologist-style clinical reports, thereby establishing a new benchmark for transparent, interpretable AI in clinical medical imaging that keeps essential human supervision while enhancing diagnostic capabilities.
Related papers
- Concept-Grounded Reasoning with Prompt-Driven Localization for Interpretable Structured Report Generation [66.62662330558906]
CORAL is a multimodal framework that integrates spatial grounding and concept-level supervision into a unified reasoning process.<n>CORAL employs a prompt-driven medical segmentation model to localize lesions and predicts multi-class clinical attributes through a Concept Bottleneck module.<n>Experiments on BUS-CoT and IU X-ray datasets demonstrate consistent improvements in diagnostic accuracy, concept consistency, and report quality over strong general-purpose and medical MLLMs.
arXiv Detail & Related papers (2026-09-14T10:21:23Z) - SMILE: Self-Explainable Multimodal Information Bottleneck for Medical Diagnosis [71.98702207668346]
Explainability is increasingly seen as a crucial requirement in AI-based medical diagnosis, particularly in safety-critical clinical decision-making.<n>This paper addresses the problem of self-explainable multimodal diagnosis by formulating it within the information bottleneck (IB) framework.<n>We propose a unified learning paradigm that jointly optimize predictive performance and modality-specific explainability.
arXiv Detail & Related papers (2026-09-04T14:13:24Z) - Beyond Fluency: A Clinical Benchmark and Anomaly-Enhanced Baseline for Spine MRI Report Generation [11.89113336167412]
We benchmark state-of-the-art Vision-Language Models (VLMs) on lumbar spine MRI with a focus on diagnostic accuracy.<n>We propose an architecture-agnostic framework that augments VLM inputs with spatially localized, disc-level anomaly heatmaps.
arXiv Detail & Related papers (2026-08-07T11:21:33Z) - Evaluating Multi-Turn Multimodal Diagnostic Reasoning on Challenging Real-World Clinical Cases [59.5328455571863]
ClinMM-Bench is the largest multi-turn multimodal clinical diagnostic evaluation benchmark to date.<n>It contains 1,089 challenging real-world clinical cases and 3,760 medical images across eight specialties.<n> proprietary models achieved the highest overall diagnostic accuracy, but the proportion of completely correct diagnoses remained limited.
arXiv Detail & Related papers (2026-07-28T16:19:03Z) - Clinical Cognition Alignment for Gastrointestinal Diagnosis with Multimodal LLMs [63.535652574541764]
Multimodal Large Language Models (MLLMs) have demonstrated remarkable potential in medical image analysis.<n>Their application in gastrointestinal endoscopy is currently hindered by two critical limitations.<n>We propose a novel Clinical-Cognitive-Aligned (CogAlign) framework to address these challenges.
arXiv Detail & Related papers (2026-03-21T07:47:37Z) - Multi-View Stenosis Classification Leveraging Transformer-Based Multiple-Instance Learning Using Real-World Clinical Data [76.89269238957593]
Coronary artery stenosis is a leading cause of cardiovascular disease, diagnosed by analyzing the coronary arteries from multiple angiography views.<n>We propose SegmentMIL, a transformer-based multi-view multiple-instance learning framework for patient-level stenosis classification.
arXiv Detail & Related papers (2026-02-02T13:07:52Z) - MIRNet: Integrating Constrained Graph-Based Reasoning with Pre-training for Diagnostic Medical Imaging [67.74482877175797]
MIRNet is a novel framework that integrates self-supervised pre-training with constrained graph-based reasoning.<n>We introduce TongueAtlas-4K, a benchmark comprising 4,000 images annotated with 22 diagnostic labels.
arXiv Detail & Related papers (2025-11-13T06:30:41Z) - An Explainable Hybrid AI Framework for Enhanced Tuberculosis and Symptom Detection [55.35661671061754]
Tuberculosis remains a critical global health issue, particularly in resource-limited and remote areas.<n>We propose a framework which enhances disease and symptom detection on chest X-rays by integrating two supervised heads and a self-supervised head.<n>Our model achieves an accuracy of 98.85% for distinguishing between COVID-19, tuberculosis, and normal cases, and a macro-F1 score of 90.09% for multilabel symptom detection.
arXiv Detail & Related papers (2025-10-21T17:18:55Z) - Ocular-Induced Abnormal Head Posture: Diagnosis and Missing Data Imputation [1.7061463565692456]
Ocular-induced abnormal head posture (AHP) is a compensatory mechanism that arises from ocular misalignment.<n>This study addresses both challenges through two complementary deep learning frameworks.<n>AHP-CADNet is a multi-level attention fusion framework for automated diagnosis.<n> curriculum learning-based imputation framework is designed to mitigate missing data.
arXiv Detail & Related papers (2025-10-07T07:51:59Z) - Ensemble Deep Learning and LLM-Assisted Reporting for Automated Skin Lesion Diagnosis [2.9307254086347427]
We introduce a unified framework that reimagines AI integration for dermatological diagnostics.<n>First, a purposefully heterogeneous ensemble of architecturally diverse convolutional neural networks provides complementary diagnostic perspectives.<n>Second, we embed large language model capabilities directly into the diagnostic workflow, transforming classification outputs into clinically meaningful assessments.
arXiv Detail & Related papers (2025-10-05T08:07:33Z) - Expert-Guided Explainable Few-Shot Learning for Medical Image Diagnosis [2.7946918847372277]
We propose an expert-guided explainable few-shot learning framework that integrates radiologist-provided regions of interest into model training.<n>We evaluate our framework on two distinct datasets: BraTS (MRI) and VinDr-CXR (Chest X-ray)<n>Our findings demonstrate the effectiveness of incorporating expert-guided attention supervision to bridge the gap between performance and interpretability in few-shot medical image diagnosis.
arXiv Detail & Related papers (2025-09-08T05:31:37Z) - XDR-LVLM: An Explainable Vision-Language Large Model for Diabetic Retinopathy Diagnosis [0.0]
We propose XDR-LVLM (eXplainable Diabetic Retinopathy Diagnosis with LVLM), a novel framework that leverages Vision-Language Large Models (LVLMs) for high-precision DR diagnosis.<n>XDR-LVLM integrates a specialized Medical Vision, an LVLM Core, and employs Multi-task Prompt Engineering and Multi-stage Fine-tuning.<n>It achieves state-of-the-art performance, with a Balanced Accuracy of 84.55% and an F1 Score of 79.92% for disease diagnosis, and superior results for concept detection.
arXiv Detail & Related papers (2025-08-21T02:14:46Z) - RadFabric: Agentic AI System with Reasoning Capability for Radiology [61.25593938175618]
RadFabric is a multi agent, multimodal reasoning framework that unifies visual and textual analysis for comprehensive CXR interpretation.<n>System employs specialized CXR agents for pathology detection, an Anatomical Interpretation Agent to map visual findings to precise anatomical structures, and a Reasoning Agent powered by large multimodal reasoning models to synthesize visual, anatomical, and clinical data into transparent and evidence based diagnoses.
arXiv Detail & Related papers (2025-06-17T03:10:33Z) - An Explainable Diagnostic Framework for Neurodegenerative Dementias via Reinforcement-Optimized LLM Reasoning [1.5646349560044959]
We propose a framework that integrates two core components to enhance diagnostic transparency.<n>First, we introduce a modular pipeline for converting 3D T1-weighted brain MRIs into textual radiology reports.<n>Second, we explore the potential of modern Large Language Models (LLMs) to assist clinicians in the differential diagnosis.
arXiv Detail & Related papers (2025-05-26T13:18:32Z) - Improving Multiple Sclerosis Lesion Segmentation Across Clinical Sites:
A Federated Learning Approach with Noise-Resilient Training [75.40980802817349]
Deep learning models have shown promise for automatically segmenting MS lesions, but the scarcity of accurately annotated data hinders progress in this area.
We introduce a Decoupled Hard Label Correction (DHLC) strategy that considers the imbalanced distribution and fuzzy boundaries of MS lesions.
We also introduce a Centrally Enhanced Label Correction (CELC) strategy, which leverages the aggregated central model as a correction teacher for all sites.
arXiv Detail & Related papers (2023-08-31T00:36:10Z)
This list is automatically generated from the titles and abstracts of the papers in this site.
This site does not guarantee the quality of this site (including all information) and is not responsible for any consequences.