MVis-Fold: A Three-Dimensional Microvascular Structure Inference Model for Super-Resolution Ultrasound

• URL: http://arxiv.org/abs/2604.04477v1
• Date: Mon, 06 Apr 2026 06:59:20 GMT
• Title: MVis-Fold: A Three-Dimensional Microvascular Structure Inference Model for Super-Resolution Ultrasound
• Abstract summary: Super-resolution ultrasound (SRUS) has overcome the resolution limitations of conventional ultrasound, enabling micrometer-scale imaging of microvasculature.<n>MVis-Fold is an innovative three-dimensional microvascular reconstruction model that integrates a cross-scale network architecture.
• Score: 13.431062279905449
• License: http://creativecommons.org/licenses/by-nc-nd/4.0/
• Abstract: Super-resolution ultrasound (SRUS) technology has overcome the resolution limitations of conventional ultrasound, enabling micrometer-scale imaging of microvasculature. However, due to the nature of imaging principles, three-dimensional reconstruction of microvasculature from SRUS remains an open challenge. We developed microvascular visualization fold (MVis-Fold), an innovative three-dimensional microvascular reconstruction model that integrates a cross-scale network architecture. This model can perform high-fidelity inference and reconstruction of three-dimensional microvascular networks from two-dimensional SRUS images. It precisely calculates key parameters in three-dimensional space that traditional two-dimensional SRUS cannot readily obtain. We validated the model's accuracy and reliability in three-dimensional microvascular reconstruction of solid tumors. This study establishes a foundation for three-dimensional quantitative analysis of microvasculature. It provides new tools and methods for diagnosis and monitoring of various diseases.

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