Introducing Anisotropic Minkowski Functionals for Local Structure
Analysis and Prediction of Biomechanical Strength of Proximal Femur Specimens
- URL: http://arxiv.org/abs/2004.01029v1
- Date: Thu, 2 Apr 2020 14:33:03 GMT
- Title: Introducing Anisotropic Minkowski Functionals for Local Structure
Analysis and Prediction of Biomechanical Strength of Proximal Femur Specimens
- Authors: Titas De
- Abstract summary: Bone fragility and fracture caused by osteoporosis or injury are prevalent in adults over the age of 50 and can reduce their quality of life.
This study proposes a new method to predict the bone strength of proximal femur specimens from quantitative multi-detector computer tomography (MDCT) images.
- Score: 0.0
- License: http://arxiv.org/licenses/nonexclusive-distrib/1.0/
- Abstract: Bone fragility and fracture caused by osteoporosis or injury are prevalent in
adults over the age of 50 and can reduce their quality of life. Hence,
predicting the biomechanical bone strength, specifically of the proximal femur,
through non-invasive imaging-based methods is an important goal for the
diagnosis of Osteoporosis as well as estimating fracture risk. Dual X-ray
absorptiometry (DXA) has been used as a standard clinical procedure for
assessment and diagnosis of bone strength and osteoporosis through bone mineral
density (BMD) measurements. However, previous studies have shown that
quantitative computer tomography (QCT) can be more sensitive and specific to
trabecular bone characterization because it reduces the overlap effects and
interferences from the surrounding soft tissue and cortical shell.
This study proposes a new method to predict the bone strength of proximal
femur specimens from quantitative multi-detector computer tomography (MDCT)
images. Texture analysis methods such as conventional statistical moments (BMD
mean), Isotropic Minkowski Functionals (IMF) and Anisotropic Minkowski
Functionals (AMF) are used to quantify BMD properties of the trabecular bone
micro-architecture. Combinations of these extracted features are then used to
predict the biomechanical strength of the femur specimens using sophisticated
machine learning techniques such as multiregression (MultiReg) and support
vector regression with linear kernel (SVRlin). The prediction performance
achieved with these feature sets is compared to the standard approach that uses
the mean BMD of the specimens and multiregression models using root mean square
error (RMSE).
Related papers
- TopoTxR: A topology-guided deep convolutional network for breast parenchyma learning on DCE-MRIs [49.69047720285225]
We propose a novel topological approach that explicitly extracts multi-scale topological structures to better approximate breast parenchymal structures.
We empirically validate emphTopoTxR using the VICTRE phantom breast dataset.
Our qualitative and quantitative analyses suggest differential topological behavior of breast tissue in treatment-na"ive imaging.
arXiv Detail & Related papers (2024-11-05T19:35:10Z) - Bone mineral density estimation from a plain X-ray image by learning
decomposition into projections of bone-segmented computed tomography [4.872603360039571]
Osteoporosis is a prevalent bone disease that causes fractures in fragile bones, leading to a decline in daily living activities.
To frequently monitor bone health, low-cost, low-dose, and ubiquitously available diagnostic methods are highly anticipated.
In this study, we aim to perform bone mineral density estimation from a plain X-ray image for opportunistic screening.
arXiv Detail & Related papers (2023-07-21T11:49:30Z) - Accelerated, physics-inspired inference of skeletal muscle
microstructure from diffusion-weighted MRI [0.0]
Current measures of skeletal muscle health take limited account of microstructural variations within muscle, which play a crucial role in mediating muscle function.
We present a physics-inspired, machine learning-based framework for the non-invasive and in vivo estimation of microstructural organization in skeletal muscle.
arXiv Detail & Related papers (2023-06-19T19:01:04Z) - A marker-less human motion analysis system for motion-based biomarker
discovery in knee disorders [60.99112047564336]
The NHS has been having increased difficulty seeing all low-risk patients, this includes but not limited to suspected osteoarthritis (OA) patients.
We propose a novel method of automated biomarker identification for diagnosis of knee disorders and the monitoring of treatment progression.
arXiv Detail & Related papers (2023-04-26T16:47:42Z) - BMD-GAN: Bone mineral density estimation using x-ray image decomposition
into projections of bone-segmented quantitative computed tomography using
hierarchical learning [1.8762753243053634]
We propose an approach using the QCT for training a generative adversarial network (GAN) and decomposing an x-ray image into a projection of bone-segmented QCT.
The evaluation of 200 patients with osteoarthritis using the proposed method demonstrated a Pearson correlation coefficient of 0.888 between the predicted and ground truth.
arXiv Detail & Related papers (2022-07-07T10:33:12Z) - Using machine learning on new feature sets extracted from 3D models of
broken animal bones to classify fragments according to break agent [53.796331564067835]
We present a new approach to fracture pattern analysis aimed at distinguishing bone fragments resulting from hominin bone breakage and those produced by carnivores.
This new method uses 3D models of fragmentary bone to extract a much richer dataset that is more transparent and replicable than feature sets previously used in fracture pattern analysis.
Supervised machine learning algorithms are properly used to classify bone fragments according to agent of breakage with average mean accuracy of 77% across tests.
arXiv Detail & Related papers (2022-05-20T20:16:21Z) - Fast and Robust Femur Segmentation from Computed Tomography Images for
Patient-Specific Hip Fracture Risk Screening [48.46841573872642]
We propose a deep neural network for fully automated, accurate, and fast segmentation of the proximal femur from CT.
Our method is apt for hip-fracture risk screening, bringing us one step closer to a clinically viable option for screening at-risk patients for hip-fracture susceptibility.
arXiv Detail & Related papers (2022-04-20T16:16:16Z) - Breast Cancer Induced Bone Osteolysis Prediction Using Temporal
Variational Auto-Encoders [65.95959936242993]
We develop a deep learning framework that can accurately predict and visualize the progression of osteolytic bone lesions.
It will assist in planning and evaluating treatment strategies to prevent skeletal related events (SREs) in breast cancer patients.
arXiv Detail & Related papers (2022-03-20T21:00:10Z) - Lumbar Bone Mineral Density Estimation from Chest X-ray Images:
Anatomy-aware Attentive Multi-ROI Modeling [23.014342480592873]
Osteoporosis is a chronic metabolic bone disease that is often under-diagnosed and under-treated due to the limited access to bone mineral density examinations.
In this paper, we propose a method to predict BMD from Chest X-ray (CXR), one of the most commonly accessible and low-cost medical imaging examinations.
arXiv Detail & Related papers (2022-01-05T22:03:32Z) - Many-to-One Distribution Learning and K-Nearest Neighbor Smoothing for
Thoracic Disease Identification [83.6017225363714]
deep learning has become the most powerful computer-aided diagnosis technology for improving disease identification performance.
For chest X-ray imaging, annotating large-scale data requires professional domain knowledge and is time-consuming.
In this paper, we propose many-to-one distribution learning (MODL) and K-nearest neighbor smoothing (KNNS) methods to improve a single model's disease identification performance.
arXiv Detail & Related papers (2021-02-26T02:29:30Z) - An Analysis by Synthesis Method that Allows Accurate Spatial Modeling of
Thickness of Cortical Bone from Clinical QCT [0.7340017786387765]
Osteoporosis is a skeletal disorder that leads to increased fracture risk due to decreased strength of cortical and trabecular bone.
We propose a novel, model based, fully automatic image analysis method that allows accurate spatial modeling of the thickness distribution of cortical bone.
arXiv Detail & Related papers (2020-09-18T07:30:18Z)
This list is automatically generated from the titles and abstracts of the papers in this site.
This site does not guarantee the quality of this site (including all information) and is not responsible for any consequences.