Classification of White Blood Cell Leukemia with Low Number of
Interpretable and Explainable Features
- URL: http://arxiv.org/abs/2201.11864v1
- Date: Fri, 28 Jan 2022 00:08:56 GMT
- Title: Classification of White Blood Cell Leukemia with Low Number of
Interpretable and Explainable Features
- Authors: William Franz Lamberti
- Abstract summary: White Blood Cell (WBC) Leukaemia is detected through image-based classification.
Convolutional Neural Networks are used to learn the features needed to classify images of cells a malignant or healthy.
This type of model requires learning a large number of parameters and is difficult to interpret and explain.
We present an XAI model which uses only 24 explainable and interpretable features and is highly competitive to other approaches by outperforming them by about 4.38%.
- Score: 0.0
- License: http://creativecommons.org/licenses/by/4.0/
- Abstract: White Blood Cell (WBC) Leukaemia is detected through image-based
classification. Convolutional Neural Networks are used to learn the features
needed to classify images of cells a malignant or healthy. However, this type
of model requires learning a large number of parameters and is difficult to
interpret and explain. Explainable AI (XAI) attempts to alleviate this issue by
providing insights to how models make decisions. Therefore, we present an XAI
model which uses only 24 explainable and interpretable features and is highly
competitive to other approaches by outperforming them by about 4.38\%. Further,
our approach provides insight into which variables are the most important for
the classification of the cells. This insight provides evidence that when labs
treat the WBCs differently, the importance of various metrics changes
substantially. Understanding the important features for classification is vital
in medical imaging diagnosis and, by extension, understanding the AI models
built in scientific pursuits.
Related papers
- Neural Cellular Automata for Lightweight, Robust and Explainable Classification of White Blood Cell Images [40.347953893940044]
We introduce a novel approach for white blood cell classification based on neural cellular automata (NCA)
Our NCA-based method is significantly smaller in terms of parameters and exhibits robustness to domain shifts.
Our results demonstrate that NCA can be used for image classification, and they address key challenges of conventional methods.
arXiv Detail & Related papers (2024-04-08T14:59:53Z) - Pathologist-Like Explanations Unveiled: an Explainable Deep Learning
System for White Blood Cell Classification [1.516937009186805]
HemaX is an explainable deep neural network-based model that produces pathologist-like explanations using five attributes.
HemaX achieves impressive results, with an average classification accuracy of 81.08% and a Jaccard index of 89.16% for cell localization.
arXiv Detail & Related papers (2023-10-20T04:59:20Z) - Tertiary Lymphoid Structures Generation through Graph-based Diffusion [54.37503714313661]
In this work, we leverage state-of-the-art graph-based diffusion models to generate biologically meaningful cell-graphs.
We show that the adopted graph diffusion model is able to accurately learn the distribution of cells in terms of their tertiary lymphoid structures (TLS) content.
arXiv Detail & Related papers (2023-10-10T14:37:17Z) - Robust and Interpretable Medical Image Classifiers via Concept
Bottleneck Models [49.95603725998561]
We propose a new paradigm to build robust and interpretable medical image classifiers with natural language concepts.
Specifically, we first query clinical concepts from GPT-4, then transform latent image features into explicit concepts with a vision-language model.
arXiv Detail & Related papers (2023-10-04T21:57:09Z) - Pixel-Level Explanation of Multiple Instance Learning Models in
Biomedical Single Cell Images [52.527733226555206]
We investigate the use of four attribution methods to explain a multiple instance learning models.
We study two datasets of acute myeloid leukemia with over 100 000 single cell images.
We compare attribution maps with the annotations of a medical expert to see how the model's decision-making differs from the human standard.
arXiv Detail & Related papers (2023-03-15T14:00:11Z) - A survey on automated detection and classification of acute leukemia and
WBCs in microscopic blood cells [6.117084972237769]
Leukemia (blood cancer) is an unusual spread of White Blood Cells or Leukocytes (WBCs) in the bone marrow and blood.
Traditional machine learning and deep learning techniques are practical roadmaps that increase the accuracy and speed in diagnosing and classifying medical images.
This paper provides a comprehensive analysis of the detection and classification of acute leukemia and WBCs in the microscopic blood cells.
arXiv Detail & Related papers (2023-03-07T14:26:08Z) - Medulloblastoma Tumor Classification using Deep Transfer Learning with
Multi-Scale EfficientNets [63.62764375279861]
We propose an end-to-end MB tumor classification and explore transfer learning with various input sizes and matching network dimensions.
Using a data set with 161 cases, we demonstrate that pre-trained EfficientNets with larger input resolutions lead to significant performance improvements.
arXiv Detail & Related papers (2021-09-10T13:07:11Z) - Relational Subsets Knowledge Distillation for Long-tailed Retinal
Diseases Recognition [65.77962788209103]
We propose class subset learning by dividing the long-tailed data into multiple class subsets according to prior knowledge.
It enforces the model to focus on learning the subset-specific knowledge.
The proposed framework proved to be effective for the long-tailed retinal diseases recognition task.
arXiv Detail & Related papers (2021-04-22T13:39:33Z) - In-Line Image Transformations for Imbalanced, Multiclass Computer Vision
Classification of Lung Chest X-Rays [91.3755431537592]
This study aims to leverage a body of literature in order to apply image transformations that would serve to balance the lack of COVID-19 LCXR data.
Deep learning techniques such as convolutional neural networks (CNNs) are able to select features that distinguish between healthy and disease states.
This study utilizes a simple CNN architecture for high-performance multiclass LCXR classification at 94 percent accuracy.
arXiv Detail & Related papers (2021-04-06T02:01:43Z) - Attention based Multiple Instance Learning for Classification of Blood
Cell Disorders [38.086308180994976]
We propose an attention based multiple instance learning method to classify blood samples of patients suffering from blood cell disorders.
With the features extracted for each cell, a multiple instance learning method classifies patient samples into one out of four blood cell disorders.
The attention mechanism provides a measure of the contribution of each cell to the overall classification and significantly improves the network's classification accuracy as well as its interpretability for the medical expert.
arXiv Detail & Related papers (2020-07-22T19:29:40Z)
This list is automatically generated from the titles and abstracts of the papers in this site.
This site does not guarantee the quality of this site (including all information) and is not responsible for any consequences.