KnowAugNet: Multi-Source Medical Knowledge Augmented Medication
Prediction Network with Multi-Level Graph Contrastive Learning
- URL: http://arxiv.org/abs/2204.11736v1
- Date: Mon, 25 Apr 2022 15:47:41 GMT
- Title: KnowAugNet: Multi-Source Medical Knowledge Augmented Medication
Prediction Network with Multi-Level Graph Contrastive Learning
- Authors: Yang An, Bo Jin, Xiaopeng Wei
- Abstract summary: This paper proposes textbfKnowAugNet, a multi-sourced medical knowledge augmented medication prediction network.
It captures the diverse relations between medical codes via multi-level graph contrastive learning framework.
It can assist doctors in making informed medication decisions for patients according to electronic medical records.
- Score: 8.71936906687061
- License: http://creativecommons.org/licenses/by/4.0/
- Abstract: Predicting medications is a crucial task in many intelligent healthcare
systems. It can assist doctors in making informed medication decisions for
patients according to electronic medical records (EMRs). However, medication
prediction is a challenging data mining task due to the complex relations
between medical codes. Most existing studies usually focus on mining the
temporal relations between medical codes while neglecting the valuable spatial
relations between heterogeneous or homogeneous medical codes, and the inherent
relations between homogeneous medical codes from hierarchical ontology graph,
which further limits the prediction performance. Therefore, to address these
limitations, this paper proposes \textbf{KnowAugNet}, a multi-sourced medical
knowledge augmented medication prediction network which can fully capture the
diverse relations between medical codes via multi-level graph contrastive
learning framework. Specifically, KnowAugNet first leverages the graph
contrastive learning using graph attention network as the encoder to capture
the implicit relations between homogeneous medical codes from the medical
ontology graph and obtains the knowledge augmented medical codes embedding
vectors. Then, it utilizes the graph contrastive learning using a weighted
graph convolutional network as the encoder to capture the correlative relations
between homogeneous or heterogeneous medical codes from the constructed medical
prior relation graph and obtains the relation augmented medical codes embedding
vectors. Finally, the augmented medical codes embedding vectors and the
supervised medical codes embedding vectors are retrieved and input to the
sequential learning network to capture the temporal relations of medical codes
and predict medications for patients.
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