UWAT-GAN: Fundus Fluorescein Angiography Synthesis via Ultra-wide-angle Transformation Multi-scale GAN

• URL: http://arxiv.org/abs/2307.11530v1
• Date: Fri, 21 Jul 2023 12:23:39 GMT
• Title: UWAT-GAN: Fundus Fluorescein Angiography Synthesis via Ultra-wide-angle Transformation Multi-scale GAN
• Authors: Zhaojie Fang, Zhanghao Chen, Pengxue Wei, Wangting Li, Shaochong Zhang, Ahmed Elazab, Gangyong Jia, Ruiquan Ge, Changmiao Wang
• Abstract summary: Fundus photography is an essential examination for clinical and differential diagnosis of fundus diseases. Current methods in fundus imaging could not produce high-resolution images and are unable to capture tiny vascular lesion areas. This paper proposes a novel conditional generative adversarial network (UWAT-GAN) to synthesize UWF-FA from UWF-SLO.
• Score: 1.165405976310311
• License: http://arxiv.org/licenses/nonexclusive-distrib/1.0/
• Abstract: Fundus photography is an essential examination for clinical and differential diagnosis of fundus diseases. Recently, Ultra-Wide-angle Fundus (UWF) techniques, UWF Fluorescein Angiography (UWF-FA) and UWF Scanning Laser Ophthalmoscopy (UWF-SLO) have been gradually put into use. However, Fluorescein Angiography (FA) and UWF-FA require injecting sodium fluorescein which may have detrimental influences. To avoid negative impacts, cross-modality medical image generation algorithms have been proposed. Nevertheless, current methods in fundus imaging could not produce high-resolution images and are unable to capture tiny vascular lesion areas. This paper proposes a novel conditional generative adversarial network (UWAT-GAN) to synthesize UWF-FA from UWF-SLO. Using multi-scale generators and a fusion module patch to better extract global and local information, our model can generate high-resolution images. Moreover, an attention transmit module is proposed to help the decoder learn effectively. Besides, a supervised approach is used to train the network using multiple new weighted losses on different scales of data. Experiments on an in-house UWF image dataset demonstrate the superiority of the UWAT-GAN over the state-of-the-art methods. The source code is available at: https://github.com/Tinysqua/UWAT-GAN.

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