INSIGHT: Explainable Weakly-Supervised Medical Image Analysis
- URL: http://arxiv.org/abs/2412.02012v2
- Date: Sun, 08 Dec 2024 16:58:40 GMT
- Title: INSIGHT: Explainable Weakly-Supervised Medical Image Analysis
- Authors: Wenbo Zhang, Junyu Chen, Christopher Kanan,
- Abstract summary: INSIGHT is a novel weakly-supervised aggregator that integrates heatmap generation as an inductive bias.
On CT and WSI benchmarks, INSIGHT achieves state-of-the-art classification results and high weakly-labeled semantic segmentation performance.
- Score: 20.635521620900978
- License:
- Abstract: Due to their large sizes, volumetric scans and whole-slide pathology images (WSIs) are often processed by extracting embeddings from local regions and then an aggregator makes predictions from this set. However, current methods require post-hoc visualization techniques (e.g., Grad-CAM) and often fail to localize small yet clinically crucial details. To address these limitations, we introduce INSIGHT, a novel weakly-supervised aggregator that integrates heatmap generation as an inductive bias. Starting from pre-trained feature maps, INSIGHT employs a detection module with small convolutional kernels to capture fine details and a context module with a broader receptive field to suppress local false positives. The resulting internal heatmap highlights diagnostically relevant regions. On CT and WSI benchmarks, INSIGHT achieves state-of-the-art classification results and high weakly-labeled semantic segmentation performance. Project website and code are available at: https://zhangdylan83.github.io/ewsmia/
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