MedCoT: Medical Chain of Thought via Hierarchical Expert
- URL: http://arxiv.org/abs/2412.13736v1
- Date: Wed, 18 Dec 2024 11:14:02 GMT
- Title: MedCoT: Medical Chain of Thought via Hierarchical Expert
- Abstract summary: This paper presents MedCoT, a novel hierarchical expert verification reasoning chain method.<n>It is designed to enhance interpretability and accuracy in biomedical imaging inquiries.<n> Experimental evaluations on four standard Med-VQA datasets demonstrate that MedCoT surpasses existing state-of-the-art approaches.
- Score: 48.91966620985221
- License: http://arxiv.org/licenses/nonexclusive-distrib/1.0/
- Abstract: Artificial intelligence has advanced in Medical Visual Question Answering (Med-VQA), but prevalent research tends to focus on the accuracy of the answers, often overlooking the reasoning paths and interpretability, which are crucial in clinical settings. Besides, current Med-VQA algorithms, typically reliant on singular models, lack the robustness needed for real-world medical diagnostics which usually require collaborative expert evaluation. To address these shortcomings, this paper presents MedCoT, a novel hierarchical expert verification reasoning chain method designed to enhance interpretability and accuracy in biomedical imaging inquiries. MedCoT is predicated on two principles: The necessity for explicit reasoning paths in Med-VQA and the requirement for multi-expert review to formulate accurate conclusions. The methodology involves an Initial Specialist proposing diagnostic rationales, followed by a Follow-up Specialist who validates these rationales, and finally, a consensus is reached through a vote among a sparse Mixture of Experts within the locally deployed Diagnostic Specialist, which then provides the definitive diagnosis. Experimental evaluations on four standard Med-VQA datasets demonstrate that MedCoT surpasses existing state-of-the-art approaches, providing significant improvements in performance and interpretability.
Related papers
- MedReaMM: Evaluating Large Multimodal Models on Expert-Level Clinical Diagnostic Synthesis [61.266743965495884]
We introduce MedReaMM, a benchmark designed to evaluate models' ability to synthesize heterogeneous clinical evidence.<n>MedReaMM comprises 625 expert-validated cases with an average of 2.79 medical images per case and a total of 1,042 standardized diagnoses annotated with ICD-11 codes.<n>We evaluate 23 Large Multimodal Models (LMMs) and find that most achieve diagnostic accuracy scores below 50%, underscoring a substantial gap in multimodal diagnostic synthesis capability.
arXiv Detail & Related papers (2026-08-23T09:37:53Z) - MedProbeBench: Systematic Benchmarking at Deep Evidence Integration for Expert-level Medical Guideline [36.04538037217031]
Deep research systems can retrieve, synthesize, and reason over large-scale external knowledge.<n>Existing benchmarks fail to evaluate this capability in realistic requiring multi-step evidence integration and expert-level judgment.<n>MedProbeBench is the first benchmark leveraging high-quality clinical guidelines as expert-level references.
arXiv Detail & Related papers (2026-04-20T15:37:46Z) - MedLayBench-V: A Large-Scale Benchmark for Expert-Lay Semantic Alignment in Medical Vision Language Models [2.0221473384338884]
We introduce MedLayBench-V, the first large-scale multimodal benchmark dedicated to expert-lay semantic alignment.<n>MedLayBench-V provides a verified foundation for training and evaluating next-generation Med-VLMs capable of bridging the communication divide between clinical experts and patients.
arXiv Detail & Related papers (2026-04-07T11:39:41Z) - MedAD-R1: Eliciting Consistent Reasoning in Interpretible Medical Anomaly Detection via Consistency-Reinforced Policy Optimization [46.65200216642429]
We introduce MedAD-38K, the first large-scale, multi-modal, and multi-center benchmark for MedAD featuring diagnostic Chain-of-Thought (CoT) annotations alongside structured Visual Question-Answering (VQA) pairs.<n>Our proposed model, MedAD-R1, achieves state-of-the-art (SOTA) performance on the MedAD-38K benchmark, outperforming strong baselines by more than 10%.
arXiv Detail & Related papers (2026-02-01T07:56:10Z) - MMedExpert-R1: Strengthening Multimodal Medical Reasoning via Domain-Specific Adaptation and Clinical Guideline Reinforcement [63.82954136824963]
Medical Vision-Language Models excel at perception tasks with complex clinical reasoning required in real-world scenarios.<n>We propose a novel reasoning MedVLM that addresses these challenges through domain-specific adaptation and guideline reinforcement.
arXiv Detail & Related papers (2026-01-16T02:32:07Z) - MedAlign: A Synergistic Framework of Multimodal Preference Optimization and Federated Meta-Cognitive Reasoning [52.064286116035134]
We develop MedAlign, a framework to ensure visually accurate LVLM responses for Medical Visual Question Answering (Med-VQA)<n>We first propose a multimodal Direct Preference Optimization (mDPO) objective to align preference learning with visual context.<n>We then design a Retrieval-Aware Mixture-of-Experts (RA-MoE) architecture that utilizes image and text similarity to route queries to a specialized and context-augmented LVLM.
arXiv Detail & Related papers (2025-10-24T02:11:05Z) - RAD: Towards Trustworthy Retrieval-Augmented Multi-modal Clinical Diagnosis [56.373297358647655]
Retrieval-Augmented Diagnosis (RAD) is a novel framework that injects external knowledge into multimodal models directly on downstream tasks.<n>RAD operates through three key mechanisms: retrieval and refinement of disease-centered knowledge from multiple medical sources, a guideline-enhanced contrastive loss transformer, and a dual decoder.
arXiv Detail & Related papers (2025-09-24T10:36:14Z) - MedCoT-RAG: Causal Chain-of-Thought RAG for Medical Question Answering [4.285647375182588]
Large language models (LLMs) have shown promise in medical question answering but often struggle with hallucinations and shallow reasoning.<n>Retrieval-augmented generation (RAG) offers a practical and privacy-preserving way to enhance LLMs with external medical knowledge.<n>We introduce MedCoT-RAG, a domain-specific framework that combines causal-aware document retrieval with structured chain-of-thought prompting.
arXiv Detail & Related papers (2025-08-20T05:43:26Z) - Multimodal Attention-Aware Fusion for Diagnosing Distal Myopathy: Evaluating Model Interpretability and Clinician Trust [19.107204920543676]
Distal myopathy represents a heterogeneous group of skeletal muscle disorders with broad clinical manifestations.<n>We propose a novel multimodal attention-aware fusion architecture that combines features extracted from two distinct deep learning models.<n>Our approach integrates these features through an attention gate mechanism, enhancing both predictive performance and interpretability.
arXiv Detail & Related papers (2025-08-02T11:08:55Z) - Medical Reasoning in the Era of LLMs: A Systematic Review of Enhancement Techniques and Applications [59.721265428780946]
Large Language Models (LLMs) in medicine have enabled impressive capabilities, yet a critical gap remains in their ability to perform systematic, transparent, and verifiable reasoning.<n>This paper provides the first systematic review of this emerging field.<n>We propose a taxonomy of reasoning enhancement techniques, categorized into training-time strategies and test-time mechanisms.
arXiv Detail & Related papers (2025-08-01T14:41:31Z) - MedIQA: A Scalable Foundation Model for Prompt-Driven Medical Image Quality Assessment [26.185840831950063]
Existing medical IQA methods, however, struggle to generalize across diverse modalities and clinical scenarios.<n>We introduce MedIQA, the first comprehensive foundation model for medical IQA, designed to handle variability in image dimensions, modalities, anatomical regions, and types.
arXiv Detail & Related papers (2025-07-25T07:02:47Z) - Uncertainty-Driven Expert Control: Enhancing the Reliability of Medical Vision-Language Models [52.2001050216955]
Existing methods aim to enhance the performance of Medical Vision Language Model (MedVLM) by adjusting model structure, fine-tuning with high-quality data, or through preference fine-tuning.<n>We propose an expert-in-the-loop framework named Expert-Controlled-Free Guidance (Expert-CFG) to align MedVLM with clinical expertise without additional training.
arXiv Detail & Related papers (2025-07-12T09:03:30Z) - MedOrch: Medical Diagnosis with Tool-Augmented Reasoning Agents for Flexible Extensibility [38.33724495011223]
We introduce MedOrch, a novel framework that orchestrates specialized tools and reasoning agents to provide comprehensive medical decision support.<n>We evaluate MedOrch across three medical applications: Alzheimer's disease diagnosis, chest X-ray interpretation, and medical visual question answering.
arXiv Detail & Related papers (2025-05-30T21:13:12Z) - MedAgent-Pro: Towards Multi-modal Evidence-based Medical Diagnosis via Reasoning Agentic Workflow [16.089816031251335]
Multi-modal Large Language Models (MLLMs) have gained significant attention and achieved success across various domains.
They lack detailed perception of visual inputs, limiting their ability to perform quantitative image analysis.
We propose MedAgent-Pro, an evidence-based reasoning agentic system designed to achieve reliable, explainable, and precise medical diagnoses.
arXiv Detail & Related papers (2025-03-21T14:04:18Z) - Uncertainty-aware abstention in medical diagnosis based on medical texts [87.88110503208016]
This study addresses the critical issue of reliability for AI-assisted medical diagnosis.
We focus on the selection prediction approach that allows the diagnosis system to abstain from providing the decision if it is not confident in the diagnosis.
We introduce HUQ-2, a new state-of-the-art method for enhancing reliability in selective prediction tasks.
arXiv Detail & Related papers (2025-02-25T10:15:21Z) - MedXpertQA: Benchmarking Expert-Level Medical Reasoning and Understanding [20.83722922095852]
MedXpertQA includes 4,460 questions spanning 17 specialties and 11 body systems.
MM introduces expert-level exam questions with diverse images and rich clinical information.
arXiv Detail & Related papers (2025-01-30T14:07:56Z) - Hierarchical Divide-and-Conquer for Fine-Grained Alignment in LLM-Based Medical Evaluation [31.061600616994145]
HDCEval is built on a set of fine-grained medical evaluation guidelines developed in collaboration with professional doctors.
The framework decomposes complex evaluation tasks into specialized subtasks, each evaluated by expert models.
This hierarchical approach ensures that each aspect of the evaluation is handled with expert precision, leading to a significant improvement in alignment with human evaluators.
arXiv Detail & Related papers (2025-01-12T07:30:49Z) - Medchain: Bridging the Gap Between LLM Agents and Clinical Practice through Interactive Sequential Benchmarking [58.25862290294702]
We present MedChain, a dataset of 12,163 clinical cases that covers five key stages of clinical workflow.<n>We also propose MedChain-Agent, an AI system that integrates a feedback mechanism and a MCase-RAG module to learn from previous cases and adapt its responses.
arXiv Detail & Related papers (2024-12-02T15:25:02Z) - MedAide: Towards an Omni Medical Aide via Specialized LLM-based Multi-Agent Collaboration [16.062646854608094]
Large Language Model (LLM)-driven interactive systems currently show potential promise in healthcare domains.
This paper proposes MedAide, an omni medical multi-agent collaboration framework for specialized healthcare services.
arXiv Detail & Related papers (2024-10-16T13:10:27Z) - A Spectrum Evaluation Benchmark for Medical Multi-Modal Large Language Models [57.88111980149541]
We introduce Asclepius, a novel Med-MLLM benchmark that assesses Med-MLLMs in terms of distinct medical specialties and different diagnostic capacities.<n>Grounded in 3 proposed core principles, Asclepius ensures a comprehensive evaluation by encompassing 15 medical specialties.<n>We also provide an in-depth analysis of 6 Med-MLLMs and compare them with 3 human specialists.
arXiv Detail & Related papers (2024-02-17T08:04:23Z) - Emulating Human Cognitive Processes for Expert-Level Medical
Question-Answering with Large Language Models [0.23463422965432823]
BooksMed is a novel framework based on a Large Language Model (LLM)
It emulates human cognitive processes to deliver evidence-based and reliable responses.
We present ExpertMedQA, a benchmark comprised of open-ended, expert-level clinical questions.
arXiv Detail & Related papers (2023-10-17T13:39:26Z) - Validating polyp and instrument segmentation methods in colonoscopy through Medico 2020 and MedAI 2021 Challenges [58.32937972322058]
"Medico automatic polyp segmentation (Medico 2020)" and "MedAI: Transparency in Medical Image (MedAI 2021)" competitions.
We present a comprehensive summary and analyze each contribution, highlight the strength of the best-performing methods, and discuss the possibility of clinical translations of such methods into the clinic.
arXiv Detail & Related papers (2023-07-30T16:08:45Z) - SHAMSUL: Systematic Holistic Analysis to investigate Medical
Significance Utilizing Local interpretability methods in deep learning for
chest radiography pathology prediction [1.0138723409205497]
The study delves into the application of four well-established interpretability methods: Local Interpretable Model-agnostic Explanations (LIME), Shapley Additive exPlanations (SHAP), Gradient-weighted Class Activation Mapping (Grad-CAM) and Layer-wise Relevance Propagation (LRP)
Our analysis encompasses both single-label and multi-label predictions, providing a comprehensive and unbiased assessment through quantitative and qualitative investigations, which are compared against human expert annotation.
arXiv Detail & Related papers (2023-07-16T11:10:35Z) - Semi-Supervised Variational Reasoning for Medical Dialogue Generation [70.838542865384]
Two key characteristics are relevant for medical dialogue generation: patient states and physician actions.
We propose an end-to-end variational reasoning approach to medical dialogue generation.
A physician policy network composed of an action-classifier and two reasoning detectors is proposed for augmented reasoning ability.
arXiv Detail & Related papers (2021-05-13T04:14:35Z) - Inheritance-guided Hierarchical Assignment for Clinical Automatic
Diagnosis [50.15205065710629]
Clinical diagnosis, which aims to assign diagnosis codes for a patient based on the clinical note, plays an essential role in clinical decision-making.
We propose a novel framework to combine the inheritance-guided hierarchical assignment and co-occurrence graph propagation for clinical automatic diagnosis.
arXiv Detail & Related papers (2021-01-27T13:16:51Z)
This list is automatically generated from the titles and abstracts of the papers in this site.
This site does not guarantee the quality of this site (including all information) and is not responsible for any consequences.