Precise Insulin Delivery for Artificial Pancreas: A Reinforcement Learning Optimized Adaptive Fuzzy Control Approach
- URL: http://arxiv.org/abs/2503.06701v1
- Date: Sun, 09 Mar 2025 17:34:09 GMT
- Title: Precise Insulin Delivery for Artificial Pancreas: A Reinforcement Learning Optimized Adaptive Fuzzy Control Approach
- Authors: Omar Mameche, Abdelhadi Abedou, Taqwa Mezaache, Mohamed Tadjine,
- Abstract summary: This paper explores the application of reinforcement learning to optimize the parameters of a Type-1 Takagi-Sugeno fuzzy controller.<n>The study's findings demonstrate that this approach significantly enhances the robustness of the controller against variations in meal size and timing.
- Score: 0.0
- License: http://arxiv.org/licenses/nonexclusive-distrib/1.0/
- Abstract: This paper explores the application of reinforcement learning to optimize the parameters of a Type-1 Takagi-Sugeno fuzzy controller, designed to operate as an artificial pancreas for Type 1 diabetes. The primary challenge in diabetes management is the dynamic nature of blood glucose levels, which are influenced by several factors such as meal intake and timing. Traditional controllers often struggle to adapt to these changes, leading to suboptimal insulin administration. To address this issue, we employ a reinforcement learning agent tasked with adjusting 27 parameters of the Takagi-Sugeno fuzzy controller at each time step, ensuring real-time adaptability. The study's findings demonstrate that this approach significantly enhances the robustness of the controller against variations in meal size and timing, while also stabilizing glucose levels with minimal exogenous insulin. This adaptive method holds promise for improving the quality of life and health outcomes for individuals with Type 1 diabetes by providing a more responsive and precise management tool. Simulation results are given to highlight the effectiveness of the proposed approach.
Related papers
- Integrating Biological-Informed Recurrent Neural Networks for Glucose-Insulin Dynamics Modeling [1.2256664621079256]
This study introduces a Biological-Informed Recurrent Neural Network (BIRNN) framework to address these limitations.
The framework is validated using the commercial UVA/Padova simulator, outperforming traditional linear models in glucose prediction accuracy and reconstruction of unmeasured states.
Results demonstrate the potential of BIRNN for personalized glucose regulation and future adaptive control strategies in AP systems.
arXiv Detail & Related papers (2025-03-24T21:26:12Z) - Domain Adaptive Diabetic Retinopathy Grading with Model Absence and Flowing Data [45.75724873443564]
Domain shift poses a significant challenge in clinical applications, e.g., Diabetic Retinopathy grading.<n>We propose a novel approach, Generative Unadversarial ExampleS (GUES), which enables adaptation from a data-centric perspective.
arXiv Detail & Related papers (2024-12-02T07:14:25Z) - From Glucose Patterns to Health Outcomes: A Generalizable Foundation Model for Continuous Glucose Monitor Data Analysis [47.23780364438969]
We present GluFormer, a generative foundation model for CGM data that learns nuanced glycemic patterns and translates them into predictive representations of metabolic health.<n>GluFormer generalizes to 19 external cohorts spanning different ethnicities and ages, 5 countries, 8 CGM devices, and diverse pathophysiological states.<n>In a longitudinal study of 580 adults with CGM data and 12-year follow-up, GluFormer identifies individuals at elevated risk of developing diabetes more effectively than blood HbA1C%.
arXiv Detail & Related papers (2024-08-20T13:19:06Z) - Attention Networks for Personalized Mealtime Insulin Dosing in People with Type 1 Diabetes [0.30723404270319693]
We demonstrate how a reinforcement learning agent, employing a self-attention encoder network, can effectively mimic and enhance this intuitive process.
Results reveal a significant reduction in glycemic risk, from 16.5 to 9.6 in scenarios using sensor-augmented pump and from 9.1 to 6.7 in scenarios using automated insulin delivery.
arXiv Detail & Related papers (2024-06-18T17:59:32Z) - Toward Short-Term Glucose Prediction Solely Based on CGM Time Series [4.7066018521459725]
TimeGlu is an end-to-end pipeline for short-term glucose prediction based on CGM time series data.
It achieves state-of-the-art performance without the need for additional personal data from patients.
arXiv Detail & Related papers (2024-04-18T06:02:12Z) - Neural Control System for Continuous Glucose Monitoring and Maintenance [0.0]
We provide a novel neural control system for continuous glucose monitoring and management.
Our approach, led by a sophisticated neural policy and differentiable modeling, constantly adjusts insulin supply in real-time.
This end-to-end method maximizes efficiency, providing personalized care and improved health outcomes.
arXiv Detail & Related papers (2024-02-21T14:56:36Z) - Hybrid Control Policy for Artificial Pancreas via Ensemble Deep
Reinforcement Learning [13.783833824324333]
We propose a hybrid control policy for the artificial pancreas (HyCPAP) to address the challenges of closed-loop glucose control.
We conduct extensive experiments using the FDA-accepted UVA/Padova T1DM simulator.
Our approaches achieve the highest percentage of time spent in the desired euglycemic range and the lowest occurrences of hypoglycemia.
arXiv Detail & Related papers (2023-07-13T00:53:09Z) - Automatic diagnosis of knee osteoarthritis severity using Swin
transformer [55.01037422579516]
Knee osteoarthritis (KOA) is a widespread condition that can cause chronic pain and stiffness in the knee joint.
We propose an automated approach that employs the Swin Transformer to predict the severity of KOA.
arXiv Detail & Related papers (2023-07-10T09:49:30Z) - Hyper-parameter Adaptation of Conformer ASR Systems for Elderly and
Dysarthric Speech Recognition [64.9816313630768]
Fine-tuning is often used to exploit the large quantities of non-aged and healthy speech pre-trained models.
This paper investigates hyper- parameter adaptation for Conformer ASR systems that are pre-trained on the Librispeech corpus.
arXiv Detail & Related papers (2023-06-27T07:49:35Z) - On the Challenges of using Reinforcement Learning in Precision Drug
Dosing: Delay and Prolongedness of Action Effects [42.84123628139412]
Two major challenges of using RL for drug dosing are delayed and prolonged effects of administering medications.
We propose a simple and effective approach to converting drug dosing PAE-POMDPs into MDPs.
We validate the proposed approach on a toy task, and a challenging glucose control task, for which we devise a clinically-inspired reward function.
arXiv Detail & Related papers (2023-01-02T03:16:59Z) - Learning Compliance Adaptation in Contact-Rich Manipulation [81.40695846555955]
We propose a novel approach for learning predictive models of force profiles required for contact-rich tasks.
The approach combines an anomaly detection based on Bidirectional Gated Recurrent Units (Bi-GRU) and an adaptive force/impedance controller.
arXiv Detail & Related papers (2020-05-01T05:23:34Z)
This list is automatically generated from the titles and abstracts of the papers in this site.
This site does not guarantee the quality of this site (including all information) and is not responsible for any consequences.