E-MRL: Cross-view Aligned Evidence-driven Multimodal Reinforcement Learning for Reliable 3D Tumor Analysis
- URL: http://arxiv.org/abs/2606.23888v1
- Date: Mon, 22 Jun 2026 19:34:47 GMT
- Title: E-MRL: Cross-view Aligned Evidence-driven Multimodal Reinforcement Learning for Reliable 3D Tumor Analysis
- Abstract summary: Cross-view aligned Evidence-driven Multimodal Reinforcement Learning (Evidence-MRL)<n>Our model is explicitly trained to identify a "key evidence slice" alongside the global diagnostic report, grounding its findings in verifiable visual evidence.<n> Experiments on large-scale 3D CT tumor datasets demonstrate that E-MRL significantly reduces hallucinations and improves diagnostic accuracy compared to SFT and RL baselines.
- Score: 19.161238848856712
- License: http://arxiv.org/licenses/nonexclusive-distrib/1.0/
- Abstract: While Vision-Language Models (VLMs) show great promise in volumetric medical report generation, they frequently suffer from visual hallucinations and a lack of grounding in 3D CT data. Current Supervised Fine-Tuning (SFT) and Reinforcement Learning (RL) strategies typically optimize text fidelity alone, essentially rewarding correct diagnoses derived from language priors rather than genuine visual perception. To address this, we propose cross-view aligned Evidence-driven Multimodal Reinforcement Learning (Evidence-MRL, noted as E-MRL), a reliable RL reasoning framework that formulates the generation process as a Markov Decision Process of "diagnosis-localization-verification". Unlike standard approaches, our model is explicitly trained to identify a "key evidence slice" alongside the global diagnostic report, grounding its findings in verifiable visual evidence. Crucially, we introduce a novel cross-view consistency reward, which validates the semantic alignment between the golden-standard report and a local visual re-query of the selected key slice, providing additional rewards for correctly-localized reasoning. Experiments on large-scale 3D CT tumor datasets demonstrate that E-MRL significantly reduces hallucinations and improves diagnostic accuracy compared to SFT and RL baselines, offering a clinically interpretable solution for visually-grounded and tumor analysis.
Related papers
- Concept-Grounded Reasoning with Prompt-Driven Localization for Interpretable Structured Report Generation [66.62662330558906]
CORAL is a multimodal framework that integrates spatial grounding and concept-level supervision into a unified reasoning process.<n>CORAL employs a prompt-driven medical segmentation model to localize lesions and predicts multi-class clinical attributes through a Concept Bottleneck module.<n>Experiments on BUS-CoT and IU X-ray datasets demonstrate consistent improvements in diagnostic accuracy, concept consistency, and report quality over strong general-purpose and medical MLLMs.
arXiv Detail & Related papers (2026-09-14T10:21:23Z) - Disease-Centric Vision-Language Pretraining with Hybrid Visual Encoding for 3D Computed Tomography [75.7789001619107]
Vision-language pre-training holds great promise for general-purpose medical AI.<n>We propose a tailored framework featuring three key components.<n>A diagnosis-aware prompt strategy employs real clinical phrases and aggregated disease prototypes to bridge the pre-training-inference gap.
arXiv Detail & Related papers (2026-06-24T08:24:45Z) - Brain-Adapter: A Dual-Stream Vision-Language MIL Framework for Comprehensive 3D CT Diagnosis of Acute Intracranial Pathologies [8.984636910625886]
Brain-Adapter is a novel dual-stream multiple instance learning framework.<n>Our method significantly outperforms state-of-the-art 3D models and standard MIL approaches.
arXiv Detail & Related papers (2026-06-22T15:41:16Z) - Regulating Anatomy-Aware Rewards via Trajectory-Integral Feedback for Volumetric Computed Tomography Analysis [30.439440028190944]
We introduce textbfClinical Abnormality Benchmarking Substrate (CABS), a structured system that decomposes radiology reports into verifiable clinical semantic units.<n>We propose textbfTrajectory-Integral FeedbackO (TIF-GRPO), a novel framework integrating control-theoretic principles into policy optimization.
arXiv Detail & Related papers (2026-05-19T04:33:27Z) - MedScribe: Clinically Grounded CT Reporting through Agentic Workflows [13.40306812882295]
Vision-language models (VLMs) have shown potential for automated radiology report generation.<n>We introduce MedScribe, a hypothesis-driven framework that reformulates report generation as an iterative evidence acquisition process.
arXiv Detail & Related papers (2026-05-03T08:32:40Z) - Clinical Cognition Alignment for Gastrointestinal Diagnosis with Multimodal LLMs [63.535652574541764]
Multimodal Large Language Models (MLLMs) have demonstrated remarkable potential in medical image analysis.<n>Their application in gastrointestinal endoscopy is currently hindered by two critical limitations.<n>We propose a novel Clinical-Cognitive-Aligned (CogAlign) framework to address these challenges.
arXiv Detail & Related papers (2026-03-21T07:47:37Z) - Concept-Enhanced Multimodal RAG: Towards Interpretable and Accurate Radiology Report Generation [12.226029763256962]
Radiology Report Generation through Vision-Language Models (VLMs) promises to reduce documentation burden, improve reporting consistency, and accelerate clinical adoption.<n>Existing research treats interpretability and accuracy as separate objectives, with concept-based explainability techniques focusing primarily on transparency.<n>We present Concept-Enhanced Multimodal RAG (CEMRAG), a unified framework that decomposes visual representations into interpretable clinical concepts.
arXiv Detail & Related papers (2026-02-17T15:18:07Z) - Med3D-R1: Incentivizing Clinical Reasoning in 3D Medical Vision-Language Models for Abnormality Diagnosis [20.302134776419955]
We propose a reinforcement learning framework with a two-stage training process: Supervised Fine-Tuning (SFT) and Reinforcement Learning (RL)<n>In RL stage, we redesign the consistency reward to explicitly promote coherent, step-by-step diagnostic reasoning.<n>Our model attains state-of-the-art accuracies of 41.92% on CT-RATE and 44.99% on RAD-ChestCT.
arXiv Detail & Related papers (2026-02-01T12:43:11Z) - MedAlign: A Synergistic Framework of Multimodal Preference Optimization and Federated Meta-Cognitive Reasoning [52.064286116035134]
We develop MedAlign, a framework to ensure visually accurate LVLM responses for Medical Visual Question Answering (Med-VQA)<n>We first propose a multimodal Direct Preference Optimization (mDPO) objective to align preference learning with visual context.<n>We then design a Retrieval-Aware Mixture-of-Experts (RA-MoE) architecture that utilizes image and text similarity to route queries to a specialized and context-augmented LVLM.
arXiv Detail & Related papers (2025-10-24T02:11:05Z) - M3Ret: Unleashing Zero-shot Multimodal Medical Image Retrieval via Self-Supervision [24.846428105192405]
We train M3Ret, a unified visual encoder, without any modality-specific customization.<n>It successfully learns transferable representations using both generative (MAE) and contrastive (SimDINO) self-supervised learning (SSL) paradigms.<n>Our approach sets a new state-of-the-art in zero-shot image-to-image retrieval across all individual modalities, surpassing strong baselines such as DINOv3 and the text-supervised BMC-CLIP.
arXiv Detail & Related papers (2025-09-01T10:59:39Z) - 3D-CT-GPT: Generating 3D Radiology Reports through Integration of Large Vision-Language Models [51.855377054763345]
This paper introduces 3D-CT-GPT, a Visual Question Answering (VQA)-based medical visual language model for generating radiology reports from 3D CT scans.
Experiments on both public and private datasets demonstrate that 3D-CT-GPT significantly outperforms existing methods in terms of report accuracy and quality.
arXiv Detail & Related papers (2024-09-28T12:31:07Z) - C^2M-DoT: Cross-modal consistent multi-view medical report generation
with domain transfer network [67.97926983664676]
We propose a cross-modal consistent multi-view medical report generation with a domain transfer network (C2M-DoT)
C2M-DoT substantially outperforms state-of-the-art baselines in all metrics.
arXiv Detail & Related papers (2023-10-09T02:31:36Z) - Cross-Modal Causal Intervention for Medical Report Generation [107.76649943399168]
Radiology Report Generation (RRG) is essential for computer-aided diagnosis and medication guidance.<n> generating accurate lesion descriptions remains challenging due to spurious correlations from visual-linguistic biases.<n>We propose a two-stage framework named CrossModal Causal Representation Learning (CMCRL)<n> Experiments on IU-Xray and MIMIC-CXR show that our CMCRL pipeline significantly outperforms state-of-the-art methods.
arXiv Detail & Related papers (2023-03-16T07:23:55Z)
This list is automatically generated from the titles and abstracts of the papers in this site.
This site does not guarantee the quality of this site (including all information) and is not responsible for any consequences.