Integrating Implicit and Explicit Relational Biases through Graph-Based Multiple Instance Learning: A Case Study in Skin Lesion Diagnosis
- URL: http://arxiv.org/abs/2608.06037v1
- Date: Thu, 06 Aug 2026 13:47:18 GMT
- Title: Integrating Implicit and Explicit Relational Biases through Graph-Based Multiple Instance Learning: A Case Study in Skin Lesion Diagnosis
- Abstract summary: This study investigates a dual-level framework for image classification.<n>It bridges the gap between implicit representation learning and explicit structural modelling.<n> Experimental results show that combining implicit interpatch modelling with explicit graph-based messages yields the best results.
- Score: 0.0
- License: http://creativecommons.org/licenses/by/4.0/
- Abstract: Relational inductive biases are essential for capturing structural dependencies among data. This study investigates a dual-level relational framework for image classification, bridging the gap between implicit representation learning and explicit structural modelling. We begin by establishing a baseline using an EfficientNetB3 architecture. To move beyond standard convolutional biases, we adopt a patch-based strategy, employing a convolutional masked autoencoder to learn implicit inter-patch relationships through self-supervised reconstruction. We then extend this approach by incorporating explicit relational modelling, organizing the learned embeddings into various graph topologies, including grid-based, random, and k-nearest neighbour structures. Experimental results on the ISIC-2018 and ISIC-2019 skin lesion diagnosis benchmarks show that combining implicit inter-patch modelling with explicit graph-based message passing yields the best performance. On the ISIC-2018 test set, the baseline model achieves a balanced accuracy of 76.17%, which improves to 77.12% with implicit patch-based relational modelling. The fully integrated grid-structured Graph Attention Network further increases performance to 79.27%. Similarly, on ISIC-2019, the implicit approach reaches 59.84% balanced accuracy, while the combination of implicit and explicit modelling yields 60.67%.
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