Co-Heterogeneous and Adaptive Segmentation from Multi-Source and
Multi-Phase CT Imaging Data: A Study on Pathological Liver and Lesion
Segmentation
- URL: http://arxiv.org/abs/2005.13201v4
- Date: Mon, 19 Jul 2021 18:54:43 GMT
- Title: Co-Heterogeneous and Adaptive Segmentation from Multi-Source and
Multi-Phase CT Imaging Data: A Study on Pathological Liver and Lesion
Segmentation
- Authors: Ashwin Raju, Chi-Tung Cheng, Yunakai Huo, Jinzheng Cai, Junzhou Huang,
Jing Xiao, Le Lu, ChienHuang Liao and Adam P Harrison
- Abstract summary: We present a novel segmentation strategy, co-heterogenous and adaptive segmentation (CHASe)
We propose a versatile framework that fuses appearance based semi-supervision, mask based adversarial domain adaptation, and pseudo-labeling.
CHASe can further improve pathological liver mask Dice-Sorensen coefficients by ranges of $4.2% sim 9.4%$.
- Score: 48.504790189796836
- License: http://arxiv.org/licenses/nonexclusive-distrib/1.0/
- Abstract: In medical imaging, organ/pathology segmentation models trained on current
publicly available and fully-annotated datasets usually do not well-represent
the heterogeneous modalities, phases, pathologies, and clinical scenarios
encountered in real environments. On the other hand, there are tremendous
amounts of unlabelled patient imaging scans stored by many modern clinical
centers. In this work, we present a novel segmentation strategy,
co-heterogenous and adaptive segmentation (CHASe), which only requires a small
labeled cohort of single phase imaging data to adapt to any unlabeled cohort of
heterogenous multi-phase data with possibly new clinical scenarios and
pathologies. To do this, we propose a versatile framework that fuses appearance
based semi-supervision, mask based adversarial domain adaptation, and
pseudo-labeling. We also introduce co-heterogeneous training, which is a novel
integration of co-training and hetero modality learning. We have evaluated
CHASe using a clinically comprehensive and challenging dataset of multi-phase
computed tomography (CT) imaging studies (1147 patients and 4577 3D volumes).
Compared to previous state-of-the-art baselines, CHASe can further improve
pathological liver mask Dice-Sorensen coefficients by ranges of $4.2\% \sim
9.4\%$, depending on the phase combinations: e.g., from $84.6\%$ to $94.0\%$ on
non-contrast CTs.
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